Labor

劳动
  • 文章类型: Journal Article
    反向takotsubo心肌病是一种罕见疾病的罕见变种,其特征是基底球囊扩张和左心室功能障碍。虽然它会使患者严重不适并依赖重症监护,这是一个短暂的现象,最严重的症状在2-3天后消退。在学期,一名年轻女性在计划再次剖宫产前自发分娩.在分娩过程中经历身体和心理上的痛苦和真空抽取后,她因逆转塔克替诺心肌病而发生心源性休克,快速诊断为经胸超声心动图。她需要2天的重症监护支持,并取得了良好的恢复。这种非常罕见的情况应该在围产期全身不适的妇女中考虑,因为它可以快速诊断,为患者提供最佳的护理。
    Reverse takotsubo cardiomyopathy is a rare variant of a rare disease characterized by basal ballooning and dysfunction of the left ventricle. While it can render patients profoundly unwell and reliant on intensivist care, it is a transient phenomenon, with the worst symptoms subsiding after 2-3 days. At term, a young woman spontaneously entered labor prior to a planned repeat cesarean section. After experiencing physical and psychological distress during labor and a vacuum extraction, she developed cardiogenic shock from reverse takotsubo cardiomyopathy, quickly diagnosed with transthoracic echocardiogram. She required 2 days of intensive care support and made an excellent recovery. This very rare condition should be considered in systemically unwell women in the peripartum as it can be quickly diagnosed, providing patients with the best appropriate care.
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  • 文章类型: Journal Article
    背景:分娩疼痛的管理是产妇护理的关键方面,对母亲和新生儿的福祉都有影响。非药物疼痛管理(NPPM)为非洲医疗机构的分娩疼痛管理提供了安全且更容易获得的选择。
    目的:本综述旨在确定非洲医疗保健专业人员(HCP)在劳动期间使用NPPM的促进因素和障碍。
    方法:这篇综合综述是使用2013年至2023年发表的关于NPPM的文章进行的。搜索的数据库包括PubMed,CINAHL,Scopus,和EMBASE。内容分析由两名审阅者独立完成,使用归纳编码生成类别。
    结果:出现了三个主要主题:在HCP中使用NPPM的感知障碍,在这个主题下出现的类别包括缺乏培训,资源限制,缺乏优先权,文化规范和信仰,缺乏意识。第二个主题是HCP中NPPM利用的潜在促进者,生成的类别包括医疗保健提供者的知识,医疗保健提供者的积极态度,家庭支持,基础设施/工作环境,HCP的经验,和客户偏好。出现的第三个主题是HCP中使用最多的NPPM方法,背部按摩和心理支持是最常用的,而音乐和运动是HCP使用的NPPM最少的方法。
    这项研究的结果表明,HCP对NPPM的态度和知识可能是其利用的促进者或障碍。在临床上,需要使HCP对在分娩期间使用这些疼痛管理方法的益处敏感,以鼓励使用。根据这项研究的结果设计的干预措施可以促进非洲医疗机构更全面的分娩疼痛管理方法。
    BACKGROUND: The management of labor pain is a critical aspect of maternal care, with implications for the well-being of both the mother and the newborn. Nonpharmacological pain management (NPPM) offers a safe and more accessible option to labor pain management in African healthcare settings.
    OBJECTIVE: This review aims to determine the facilitators of and barriers to using NPPM during labor among healthcare professionals (HCPs) in Africa.
    METHODS: This integrative review was done using articles that focused on NPPM and published between 2013 and 2023. Databases searched include PubMed, CINAHL, SCOPUS, and EMBASE. Content analysis was done independently by two reviewers using inductive coding to generate categories.
    RESULTS: Three main themes emerged: Perceived barriers to the utilization of NPPM among HCPs, categories that emerged under this theme include lack of training, resource limitation, lack of priority, cultural norms and beliefs, and lack of awareness. The second theme is potential facilitators to the utilization of NPPM among HCP, the categories generated include healthcare provider\' knowledge, positive attitude of healthcare providers, family support, infrastructure/working environment, experiences of HCPs, and client preferences. The third theme that emerged is the most utilized methods of NPPM among HCPs, with back massage and psychological support being the most used, whereas music and exercise were the least NPPM methods used by HCPs.
    UNASSIGNED: The findings from this study show that the attitudes and knowledge of HCPs about NPPM can either be a facilitator or a barrier in its utilization. In the clinical setting, HCPs need to be sensitized on the benefits of using these methods of pain management during labor to encourage use. Interventions designed based on the findings from this study can promote a more holistic approach to labor pain management in African healthcare settings.
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  • 文章类型: Journal Article
    子痫前期是妊娠期和产后心力衰竭的重要原因。这篇综述的目的是阐明先兆子痫性心力衰竭的病理生理学和临床特征,并描述这些高危产妇的医疗和麻醉管理。本文回顾了目前有关先兆子痫心力衰竭及其病理生理学的证据基础。类型,和临床特征。我们还描述了围产期这些患者的医疗和麻醉管理。先兆子痫引起的心力衰竭可表现为收缩或舒张功能障碍。收缩性心力衰竭的管理策略包括饮食盐限制,利尿,并谨慎使用β受体阻滞剂和血管扩张剂。利尿剂是治疗舒张性心力衰竭的主要药物。在没有产科适应症的情况下,在这些高危患者中,阴道分娩是最安全的分娩方式,建议使用早期分娩硬膜外镇痛。这些患者在分娩和阴道分娩期间需要增加侵入性监测。在这些患者中,神经轴和全身麻醉已成功用于剖宫产,但需要对标准技术进行关键修改。子宫收缩性药物具有显著的心血管和肺部作用,在这些患者的治疗过程中,清楚地了解这些是至关重要的。先兆子痫伴心力衰竭需要个性化的围产期护理,心脏代偿失调是孕产妇和新生儿发病和死亡的重要危险因素。这些高危产妇受益于及时的多学科团队投入和协作管理。
    Preeclampsia is an important cause of heart failure during pregnancy and the postpartum period. The aim of this review is to elucidate the pathophysiology and clinical features of preeclamptic heart failure and describe the medical and anesthetic management of these high-risk parturients. This article reviews the current evidence base regarding preeclamptic heart failure and its pathophysiology, types, and clinical features. We also describe the medical and anesthetic management of these patients during the peripartum period. Heart failure due to preeclampsia can present as either systolic or diastolic dysfunction. The management strategies of systolic heart failure include dietary salt restriction, diuresis, and cautious use of beta-blockers and vasodilators. Diuretics are the mainstay in the treatment of diastolic heart failure. In the absence of obstetric indications, vaginal delivery is the safest mode of delivery in these high-risk patients, and the use of an early labor epidural for analgesia is recommended. These patients would require increased invasive monitoring during labor and vaginal delivery. Neuraxial and general anesthesia have been used successfully for cesarean section in these patients but require crucial modifications of the standard technique. Uterotonic drugs have significant cardiovascular and pulmonary effects, and a clear understanding of these is essential during the management of these patients. Preeclamptics with heart failure require individualized peripartum care, as cardiac decompensation is an important risk factor for maternal and neonatal morbidity and mortality. These high-risk parturients benefit from timely multidisciplinary team inputs and collaborated management.
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  • 文章类型: Journal Article
    真空提取通常被认为是与操作员相关的任务,最关注产科医生的技术能力(1-3)。关于团队和非技术技能对真空辅助分娩临床结果的影响知之甚少。本研究旨在通过分析进行实际真空提取的团队的视频记录,调查产科医生的非技术技能是否与他们的临床表现水平相关。
    我们在奥胡斯大学医院和霍森斯地区医院的每个产房中安装了两个或三个摄像机,并获得了60个管理真空抽取的团队的视频。获得了适当的同意。两名评估者仔细审查了视频,并使用产科团队绩效评估(AOTP)清单评估了团队的非技术技能,在Likert量表上对所有项目评分从1到5(1=差;3=平均;5=优)。这导致了从18到90的总分。两个不同的评估者使用TeamOBS-真空辅助分娩(VAD)清单独立评估团队的临床表现(遵守临床指南),对每个项目进行评级(0=未完成,1=做得不正确;2=做得正确)。这导致具有以下范围的总评分(低临床表现:0-59;平均:60-84;和高:85-100)。使用类内相关性(ICC)分析评分者之间的一致性,并且在Logit量表上分析了高或低临床表现的风险,以满足正常性的假设。
    获得优秀非技术成绩的团队有81%的概率获得高临床表现,而在非技术平均得分的团队中,该概率仅为12%(p<0.001)。具有高临床表现的团队通常在“团队互动”的非技术项目中表现优异,\"\"预期,\“\”避免固定,\"和\"集中沟通。“具有低或平均临床表现的团队通常忽略了镇痛,推迟放弃尝试的阴道分娩,并且没有充分使用适当的胎儿监护。两个评分者团队的评分者间可靠性都很高,非技术技能的ICC为0.83(95%置信区间[CI]:0.71-0.88),临床表现为0.84(95%CI:0.74-0.90)。
    尽管通过真空抽吸辅助阴道分娩通常被认为是依赖于操作者的任务,我们的研究结果表明,团队合作和有效的团队互动在实现高临床绩效方面发挥着至关重要的作用.团队合作帮助顾问预测下一步,避免固定,确保足够的镇痛,并在分娩期间保持全面的胎儿监护。
    UNASSIGNED: Vacuum extraction is generally considered an operator-dependent task, with most attention directed toward the obstetrician\'s technical abilities (1-3). Little is known about the effect of the team and non-technical skills on clinical outcomes in vacuum-assisted delivery. This study aimed to investigate whether the non-technical skills of obstetricians were correlated with their level of clinical performance via the analysis of video recordings of teams conducting actual vacuum extractions.
    UNASSIGNED: We installed between two or three video cameras in each delivery room at Aarhus University Hospital and Horsens Regional Hospital and obtained 60 videos of teams managing vacuum extraction. Appropriate consent was obtained. Two raters carefully reviewed the videos and assessed the teams\' non-technical skills using the Assessment of Obstetric Team Performance (AOTP) checklist, rating all items on a Likert scale score from 1 to 5 (1 = poor; 3 = average; and 5 = excellent). This resulted in a total score ranging from 18 to 90. Two different raters independently assessed the teams\' clinical performance (adherence to clinical guidelines) using the TeamOBS-Vacuum-Assisted Delivery (VAD) checklist, rating each item (0 = not done, 1 = done incorrectly; and 2 = done correctly). This resulted in a total score with the following ranges (low clinical performance: 0-59; average: 60-84; and high: 85-100). Interrater agreement was analyzed using intraclass correlation (ICC), and the risk of high or low clinical performance was analyzed on a logit scale to meet the assumption of normality.
    UNASSIGNED: Teams that received excellent non-technical scores had an 81% probability of achieving high clinical performance, whereas this probability was only 12% among teams with average non-technical scores (p < 0.001). Teams with a high clinical performance often had excellent behavior in the non-technical items of \"team interaction,\" \"anticipation,\" \"avoidance fixation,\" and \"focused communication.\" Teams with a low or average clinical performance often neglected to consider analgesia, had delayed abandonment of the attempted vaginal delivery and insufficient use of appropriate fetal monitoring. Interrater reliability was high for both rater-teams, with an ICC for the non-technical skills of 0.83 (95% confidence interval [CI]: 0.71-0.88) and 0.84 for the clinical performance (95% CI: 0.74-0.90).
    UNASSIGNED: Although assisted vaginal delivery by vacuum extraction is generally considered to be an operator-dependent task, our findings suggest that teamwork and effective team interaction play crucial roles in achieving high clinical performance. Teamwork helped the consultant anticipate the next step, avoid fixation, ensure adequate analgesia, and maintain thorough fetal monitoring during delivery.
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  • 文章类型: English Abstract
    目标:法国的引产涉及四分之一的分娩,其中70%的引产始于宫颈成熟,使用药理学(前列腺素)或机械(气球)方法。这篇综述旨在在现有知识范围内比较这两种方法,使用PRISMA方法。
    方法:比较这两种方法的试验,截至2023年7月已出版或未出版,在PubMed中搜索法语或英语,Cochrane图书馆和ClinicalTrial.govs数据集。选择了50篇文章,其中包括10689名妇女。感兴趣的结果是来自“核心成果集”中的那些关于劳动诱导(COSIOL)列表的线索:交付方式,从引产到出生的时间,孕产妇和新生儿发病率,和产妇满意度。
    结果:两种分娩方式或新生儿和产妇发病率没有差异。机械方法从诱导到出生的时间更长。这些也与对催产素的更大需求有关,子宫过度刺激较少,器械分娩较少。仅在9项试验中使用各种量表评估了产妇满意度,从而解释了产妇满意度。
    结论:这两种诱导方法对阴道分娩的疗效相似,但哪一个最符合女性满意度标准还有待观察。
    OBJECTIVE: Induction of labor in France concerns one birth out of four with 70% of induction starting by cervical ripening, either with a pharmacological (prostaglandins) or a mechanical (balloon) method. This review aims to compare these two methods within current knowledge, using the PRISMA methodology.
    METHODS: Trials comparing these two methods, published or unpublished up to July 2023, in French or English were searched for in the PubMed, Cochrane Library and ClinicalTrial.govs datasets. Fifty articles including 10,689 women were selected. The outcomes of interest were those from the Core Outcome Set for trails on Induction of Labour (COSIOL) list: mode of delivery, time from induction-to-birth, maternal and neonatal morbidity, and maternal satisfaction.
    RESULTS: No differences were observed between the two methods for the mode of delivery or neonatal and maternal morbidity. The time from induction-to-birth was longer for mechanical methods. Those were also associated with a greater need for oxytocin, less uterine hyperstimulation and less instrumental deliveries. Maternal satisfaction was assessed in only nine trials using various scales which made the interpretation of maternal satisfaction.
    CONCLUSIONS: The efficacy of these two induction methods is similar for vaginal delivery, but it remains to be seen which one best meets women\'s satisfaction criteria.
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  • 文章类型: Journal Article
    背景:本系统评价旨在阐明由于产时胎儿受损(IFC)引起的脑胎盘比率(CPR)与紧急剖宫产(CSs)之间的关系。方法:PubMed的数据集,ScienceDirect,中部,Embase,和谷歌学者被搜索到2024年1月发表的关于IFC的CPR和CS率之间关系的研究,以及CPR的预测价值。结果:搜索确定了582篇文章,其中16项观察性研究最终被纳入,他们中的大多数都有前瞻性的设计。共有14,823名患者参与其中。低CPR与IFC的CS风险较高相关。CPR的预测价值在研究中是非常不同的,这是由于关于所包括的患者组以及从CPR评估到分娩的时间间隔的显著异质性。结论:对于IFC,低CPR与较高的CS风险相关,虽然预测价值较差。可以在所有患者分娩前计算CPR,以对IFC引起的CS风险进行分层。
    Background: This systematic review aimed to clarify the association between the cerebroplacental ratio (CPR) and emergency cesarean sections (CSs) due to intrapartum fetal compromise (IFC). Methods: Datasets of PubMed, ScienceDirect, CENTRAL, Embase, and Google Scholar were searched for studies published up to January 2024 regarding the relationship between the CPR and the rate of CS for IFC, as well as the predictive value of the CPR. Results: The search identified 582 articles, of which 16 observational studies were finally included, most of them with a prospective design. A total of 14,823 patients were involved. A low CPR was associated with a higher risk of CS for IFC. The predictive value of the CPR was very different among the studies due to substantial heterogeneity regarding the group of patients included and the time interval from CPR evaluation to delivery. Conclusions: A low CPR is associated with a higher risk of CS for IFC, although with a poor predictive value. The CPR could be calculated prior to labor in all patients to stratify the risk of CS due to IFC.
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  • 文章类型: Journal Article
    比较引产期间Foley导尿管前后的Bishop评分。
    这项研究是在卡拉奇阿加汗大学医院进行的一项回顾性研究,经伦理审查委员会批准后,巴基斯坦。所有在2014年9月至2015年10月期间妊娠37周或以上使用Foley导尿管引产的妇女均纳入研究。数据在社会科学统计软件包(SPSS)19.0版中输入和分析。将通过Wilcoxon体征检验计算引产期间Foley导尿管前后Bishop评分的比较。
    引产981例,749(76.3%)接受Foley导管,与前列腺素和催产素结合使用。约68%为阴道分娩,32%为剖腹产。三分之二的女性主教<4。总的来说,然而,所有使用导管的患者的Bishop评分都有显著改善,导管放置10~12小时的患者获益最大.
    Foley\'s是更好,更安全的选择。鉴于我们的结果,建议将Foley保持10-12小时,以获得主教得分的显着改善。
    UNASSIGNED: To compare pre and post Foley\'s catheter Bishop Score during labour induction.
    UNASSIGNED: This study was a retrospective study conducted at the Aga Khan University Hospital Karachi, Pakistan after approval from ethical review board. All women who underwent induction of labour with Foley\'s Catheter at gestation of 37 weeks or more from September 2014-October 2015 were included. Data was entered and analyzed in Statistical Package for Social Sciences (SPSS) version 19.0. The comparison between pre and post Foley\'s catheter Bishop Score during labour induction will be calculated by Wilcoxon sign test.
    UNASSIGNED: There were 981 cases of inductions of labour, 749 (76.3%) received Foley\'s catheter, in combination with prostaglandins and oxytocin. About 68% were vaginal deliveries while 32% underwent C-section. Two third of women had bishop <4. Overall, Bishop score improved significantly in all patients with the catheter however, maximum benefit was seen in patients where the catheter was placed for 10-12 hours.
    UNASSIGNED: Foley\'s is the better and safer option. In view of our results, It has been recommended to keep the Foley\'s for 10-12 hours to get significant improvement in bishop score.
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  • 文章类型: Journal Article
    Childbirth is a remarkable, life-changing process and is frequently regarded as an excruciating, physically and emotionally demanding experience that women endure. Labor pain management poses a significant challenge for obstetricians and expectant mothers. Although pharmacological pain management is the gold standard, it still imposes risks on the mother and baby. Recently, non-pharmacological pain management (NPPM) has emerged as a safe, effective option. Six databases were searched for articles published up to 2023 using specific related keywords and defined inclusion and exclusion criteria. The extraction and gathering of data was made so as to be categorized into physical, psychological, and complementary NPPM techniques. In light of the enormous development and diversity of NPPM techniques, the present review aims to examine contemporary NPPM knowledge and application, discussing efficacy, advantages, limitations, and potential adverse effects, with a specific focus on women\'s individual requirements, to strengthen obstetricians\' knowledge in guiding decision-making for women in childbirth.
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  • 文章类型: Meta-Analysis
    由于对分娩过程中静脉(IV)液体的有效性和安全性的研究有限,没有可用的指导方针。因此,本荟萃分析旨在评估与常规治疗相比,产程期间静脉输注林格氏乳酸的疗效。
    在六个数据库中搜索了随机对照试验(RCT),比较了未产妇女足月分娩期间125mL/h或250mL/hr的IVRinger乳酸的影响与常规护理相比,并将搜索结果导入Covidence进行文章筛选。在使用RevMan5.4的荟萃分析模型中,将所有相关结果汇总为风险比(RR)或平均差(MD)和95%CI。
    来自7个RCT和967名未分娩妇女的汇总数据显示,分娩时间的活跃阶段(MD-32.16,95%CI[40.43至-23.90],p<0.00001),需要增加催产素(RR0.72,95%CI[0.54至0.96],p=0.03)和长期分娩的发生率(RR0.57,95%CI[0.34至0.95],p=0.03)与IV林格氏乳酸相比显着降低。然而,总产程(P=0.23),两组第二产程时间(P=0.31)和剖宫产率(P=0.070)无差异。对于活跃期的产程,基于输注率的亚组分析的检验显着(P=0.01)。
    IV林格氏乳酸减少了积极分娩的持续时间,需要增加催产素和延长分娩发生率。然而,它对新生儿即时健康的影响没有差异,但发现与不限制口服的常规护理相比,它更有可能减少产妇呕吐。需要进一步的研究来探索其在更大,更多样化的人群以及不同的静脉输液中的作用,以用于循证指南。
    Due to limited research on the effectiveness and safety of intravenous (IV) fluids administered during labor, there are no guidelines available. Thus, this meta-analysis aims to evaluate efficacy of IV Ringer\'s lactate during labor as compared to usual care.
    Six databases were searched for the randomized controlled trials (RCTs) comparing the effects of IV Ringer\'s lactate at 125 mL/h or 250 mL/hr during labor in nulliparous women at term as compared to usual care, and the search results were imported to Covidence for screening of the articles. All the concerned outcomes were pooled as risk ratios (RR) or mean difference (MD) with 95% CI in the meta-analysis models using RevMan 5.4.
    Pooled data from 7 RCTs with 967 nulliparous women showed that the active stage of labor duration (MD -32.16 with 95% CI [40.43 to -23.90], p < 0.00001), need of oxytocin augmentation (RR 0.72 with 95% CI [0.54 to 0.96], p = 0.03) and incidence of prolonged labor (RR 0.57 with 95% CI [0.34 to 0.95], p = 0.03) was significantly lower with IV Ringer\'s lactate. However, the total duration of labor (p = 0.23), duration of second stage of labor (p = 0.31) and cesarean section rate (p = 0.070) did not differ between the two groups. The test for subgroup analysis based on infusion rate was significant (p = 0.01) for the active stage of labor.
    IV Ringer\'s lactate reduced the duration of active labor, the need for oxytocin augmentation and the prolonged labor incidence. However, it did not differ in effect on immediate neonatal health but was found to have more potential for reducing maternal vomiting as compared to usual care with unrestricted oral intake. Further research is needed to explore its effects in the larger and more diverse populations and with different IV fluids for evidence-based guidelines.
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  • 文章类型: Meta-Analysis
    背景:关于分娩期间静脉(IV)液体给药的类型和速率的证据仍然没有定论,评估IV液体影响的研究结果好坏参半。
    目的:评估静脉输液速率为250mL/h与125mL/h相比对未分娩妇女分娩结局的影响。
    方法:我们通过包含相关关键词“IV水合”的搜索策略,搜索了六个数据库中的相关研究,“静脉注射液”,和“劳工”从这些数据库开始到2023年5月1日,没有任何应用限制。
    方法:将搜索结果导入Covidence,以筛选本综述的合格文章。仅包括随机对照试验(RCT),评估250mL/h的静脉输液对足月(>37周)未产妇女分娩结局的影响,与125mL/h相比。
    方法:有关纳入研究特征的数据,参与者的基线特征,在Excel电子表格中收集相关结局,并将所有相关结局汇总为风险比(RR)或均差(MD),在使用RevMan5.4的荟萃分析模型中使用95%置信区间(CI).
    结果:来自11个RCT的1815例患者的汇总数据显示,250mL/h的输液速度显着降低了剖宫产率(RR0.70,95%CI0.56-0.88,P=0.002),第一产程持续时间(MD-46.97,95%CI-81.79至-12.14,P=0.008),第二产程持续时间(MD-2.69,95%CI-4.34至-1.05,P=0.001),延长分娩发生率(RR0.72,95%CI0.58-0.89,P=0.003),与125mL/h相比。此外,阴道分娩率(RR1.07,95%CI1.02-1.12,P=0.009)较高,输注速率为250mL/h.
    结论:在未产妇分娩期间以250mL/h的速度输注静脉输液降低了剖宫产率,增加了阴道分娩率,缩短了第一和第二阶段的分娩时间,与125mL/h相比,延长分娩的发生率降低。这些发现表明,随着输液率的提高,产程进展加快,产程并发症的风险降低。然而,未来的研究涉及更多样化的人群,并探索将静脉输液速率与其他干预措施相结合的潜在益处,例如在分娩期间添加葡萄糖或较少限制的口服摄入,是需要的。
    BACKGROUND: Evidence regarding the type and rate of intravenous (IV) fluid administration during labor is still inconclusive and the studies assessing the impact of IV fluids had mixed results.
    OBJECTIVE: To evaluate the effects of IV fluids at an infusion rate of 250 mL/h as compared with 125 mL/h on labor outcomes in nulliparous women.
    METHODS: We searched six databases for relevant studies through a search strategy containing the relevant keywords \"IV hydration\", \"IV fluids\", and \"labor\" from the inception of these databases to May 1, 2023, without any applied restrictions.
    METHODS: Search results were imported to Covidence for screening of eligible articles for this review. Randomized controlled trials (RCTs) assessing the impact of IV fluids at 250 mL/h on the outcomes of labor in nulliparous women at term (>37 weeks) as compared with 125 mL/h were included only.
    METHODS: Data regarding the characteristics of included studies, participant\'s baseline characteristics, and concerned outcomes were collected in an Excel spreadsheet and all the concerned outcomes were pooled as risk ratios (RR) or mean difference (MD) with 95% confidence interval (CI) in the meta-analysis models using RevMan 5.4.
    RESULTS: Pooled data from 11 RCTs with 1815 patients showed that 250 mL/h infusion rate had a significant reduction in cesarean section rate (RR 0.70, 95% CI 0.56-0.88, P = 0.002), the first stage of labor duration (MD -46.97, 95% CI -81.79 to -12.14, P = 0.008), the second stage of labor duration (MD -2.69, 95% CI -4.34 to -1.05, P = 0.001), prolonged labor incidence (RR 0.72, 95% CI 0.58-0.89, P = 0.003), as compared with 125 mL/h. Also, the vaginal delivery rate (RR 1.07, 95% CI 1.02-1.12, P = 0.009) was higher with a 250 mL/h infusion rate.
    CONCLUSIONS: IV fluids at an infusion rate of 250 mL/h during labor in nulliparous women decreased the cesarean delivery rate, increased the vaginal delivery rate, shortened the first and second-stage labor duration, decreased the incidence of prolonged labor as compared with 125 mL/h. These findings suggest enhanced labor progression and a lower risk of labor complications with higher infusion rates. However, future research involving a more diverse population and exploring the potential benefits of combining IV infusion rates with other interventions, such as adding dextrose or less restrictive oral intake during labor, is needed.
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