背景:根据世界卫生组织(WHO),癌症是全球死亡的主要原因,在2020年造成大约1000万人死亡。天然植物产品仍然是加纳大多数疾病和疾病的广泛使用和接受的治疗形式。这篇综述研究了黑质隐球菌(Wennberg)L.Joubert。还有Bruyns.,非洲前科(Guill。还有Perr.)陶布。和PterygotamacrocarpaK.Schum。作为传统上用于治疗肿瘤生长的药用植物,在其他疾病中,在加纳的阿散蒂地区。
目的:本文旨在揭示对植物学描述的全面综述,生态分布,民族医学用途,Nigrescens的植物化学成分和民族药理学相关性,P.非洲和P.macrocarpa。
方法:本评论涵盖了1962年至2023年之间来自各个国家的作品。出版书籍,论文,关于C.nigrescens的科学和医学文章,P.Africana和P.macrocarpa从以下数据库收集;\'Elsevier\'sScopus\',\'科学直接\',\'Medline\',\'PubMed\',\'研究之门\'\'谷歌学者\',和\'Springer链接\'使用关键字。
结果:对黑丝虫进行的植物化学筛选,P.Africana和P.macrocarpa揭示了许多生物活性化合物的存在,如类黄酮,生物碱,多酚,皂苷,还有单宁.从药用植物中分离的植物提取物和化合物表现出广泛的民族药理活性,包括抗微生物,抗炎,抗氧化剂,镇痛药,细胞毒性,抗疟药,退烧药,补血,肝脏保护,壮阳药和降压特性。
结论:本综述是关于黑质隐球菌(Wennberg)L.Joubert。还有Bruyns.,非洲前科(Guill。还有Perr.)陶布。和PterygotamacrocarpaK.Schum。提供了迄今为止对这些植物进行的民族药理学研究的可靠摘要。这篇评论提供了黑丝虫的简介,P.Africana和P.macrocarpa,为未来的工作奠定了基础。此外,这些信息提供了更好地了解植物,以改善其传统和商业用途。
BACKGROUND: Cancer stands as one of the leading causes of death worldwide according to the World Health Organization (WHO), and it has led to approximately 10 million fatalities in 2020. Medicinal plants are still widely used and accepted form of treatment for most diseases including cancer in Ghana. This
review presented Cryptolepis nigrescens (Wennberg) L. Joubert. and Bruyns., Prosopsis africana (Guill. and Perr.) Taub. and Pterygota macrocarpa K. Schum. as medicinal plants that are traditionally used to treat tumour growth, amongst other diseases, in the Ashanti region of Ghana.
OBJECTIVE: This paper aims to present a comprehensive
review on the botanical description, ecological distribution, ethnomedicinal uses, phytochemical composition and ethnopharmacological relevance of C. nigrescens, P. africana and P. macrocarpa.
METHODS: The
review covers works published between 1962 and 2023 from various countries. Published books, thesis, scientific and medical articles on C. nigrescens, P. africana and P. macrocarpa were collected from the following databases: \'Scopus\', \'Science Direct\', \'Medline\', \'PubMed\', \'Research Gate\' \'Google Scholar, and \'Springer link\' using the keywords.
RESULTS: Phytochemical analysis of C. nigrescens, P. africana and P. macrocarpa revealed the presence of some prominent bioactive compounds such as convallatoxin, 7,3,4-trihydroxy-3-methoxyflavanone and dioxane, respectively. Plant extracts and isolated compounds of these medicinal plants exhibited a wide range of ethnopharmacological activities including antimicrobial, anti-inflammatory, antioxidant, analgesic, cytotoxic, antimalarial, antipyretic, haematinic, hepato-protective, aphrodisiac and antihypertensive properties.
CONCLUSIONS: The present
review on C. nigrescens , P.africana and P. macrocarpa provided a credible summary of the ethnopharmacological research conducted on these medicinal plants till date. The data also highligted the potential therapeutic profiles of these plants in Ghana that could serve as foundation for future studies. Additionally, the information significantly supported the traditional and commercial use of these plants among the people.