背景:非洲分枝杆菌是结核分枝杆菌群(MTBC)的成员,在西非流行,在那里,它导致了多达一半的肺结核病例。这里,我们报道了从结核性心包炎患者的心包积液培养物中首次分离出非洲分枝杆菌。
方法:一名31岁的男子,来自塞内加尔,出现大量心包积液和心包填塞,需要心包穿刺术。在心包液中发现了非洲分枝杆菌II型。患者完成了10个月的标准治疗,一个有利的结果。
结论:我们报告了首例由非洲分枝杆菌引起的结核性心包炎,这提供了证据表明这种微生物可以引起心包疾病,必须考虑来自出现心包积液的流行地区的患者。
BACKGROUND: Mycobacterium africanum is a member of the Mycobacterium tuberculosis complex (MTBC) and is endemic in West Africa, where it causes up to half of all cases of pulmonary tuberculosis. Here, we report the first isolation of Mycobacterium africanum from the pericardial effusion culture of a patient with tuberculous pericarditis.
METHODS: A 31-year-old man, native from Senegal, came to the emergency room with massive pericardial effusion and cardiac tamponade requiring pericardiocentesis. M. africanum subtype II was identified in the pericardial fluid. The patient completed 10 months of standard treatment, with a favorable outcome.
CONCLUSIONS: We report the first
case of tuberculous pericarditis caused by Mycobacterium africanum, which provide evidence that this microorganism can cause pericardial disease and must be considered in patients from endemic areas presenting with pericardial effusion.