Maleae部落由一千多个物种组成，包括许多众所周知的具有广泛生物学特性的含多酚水果作物，例如，苹果（苹果），浆果（Aronia），梨(Pyrus),quences(Cydonia,木瓜)，萨斯卡通（Amelanchier），枇杷（Eriobotrya），枸杞（Mespilus），罗文（Sorbus），和山楂（Crataegus）。考虑到目前对功能性食品概念的兴趣和仍然不足的糖尿病管理方法，水果的抗糖尿病潜力已经被深入研究，包括Maleae部落的人.本文首先综合概述了本选题,涵盖2000年至2023年发表的文章(共131篇)。本综述的第一部分侧重于迄今为止研究的水果（46种）的潜在作用机制，包括它们对组织特异性葡萄糖转运和胰岛素信号通路中蛋白质表达或活性的影响。第二部分涵盖负责特定水果活性的植物化合物-主要是多酚(例如，黄酮醇，二氢查耳酮,原花青素，花青素,酚酸)，还有多糖，三萜,以及它们的累加和协同效应。总之,来自Maleae部落的水果似乎有希望作为功能性食品和抗糖尿病药物;然而，他们更广泛的健康应用前景需要进一步研究，尤其是更深刻的体内试验。
The Maleae tribe consists of over one thousand species, including many well-known polyphenol-containing fruit crops with wide-ranging biological properties, e.g., apples (Malus), chokeberries (Aronia), pears (Pyrus), quinces (Cydonia, Chaenomeles), saskatoon (Amelanchier), loquats (Eriobotrya), medlars (Mespilus), rowans (Sorbus), and hawthorns (Crataegus). Considering the current interest in the concept of functional foods and the still-insufficient methods of diabetes management, the anti-diabetic potential of fruits has been studied intensively, including those of the Maleae tribe. This paper is the first comprehensive overview of this selected topic, covering articles published from 2000 to 2023 (131 articles in total). The first part of this
review focuses on the potential mechanisms of action of fruits investigated so far (46 species), including their effects on tissue-specific glucose transport and the expression or activity of proteins in the insulin signalling pathway. The second part covers the phytocompounds responsible for particular fruits\' activity-primarily polyphenols (e.g., flavonols, dihydrochalcones, proanthocyanidins, anthocyanins, phenolic acids), but also polysaccharides, triterpenes, and their additive and synergistic effects. In summary, fruits from the Maleae tribe seem promising as functional foods and anti-diabetic agents; however, their prospects for more expansive pro-health application require further research, especially more profound in vivo trials.
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