■该研究旨在调查精神分裂症谱系障碍(ICD-10:F20-F29)发病率的时间趋势,双相情感障碍(ICD-10:F30,F31),和复发性抑郁症(ICD-10:F33),并调查所有事件病例的就业率。
■我们使用了2000年至2013年丹麦所有精神病住院患者和门诊患者接触的全国纵向数据。计算三个诊断组的年龄调整后的发病率比率,和就业率,教育,和残疾抚恤金在所有事件病例诊断前1年和诊断后2年进行测量。
■所有诊断组和男女的发病率均显着增加。比较2013年与2000年的发病率,精神分裂症谱系障碍的发病率为1.67(95%CI1.51-1.84),3.82(95%CI3.23-4.52)用于双相情感障碍,和2.80(95%CI2.58-3.04)为复发性抑郁症。在同一观察期间,就业率下降,在所有三个亚组诊断前1年和诊断后2年.2002年,就业率,确诊后2年,精神分裂症谱系障碍占24.6%,双相情感障碍为35.0%,复发性抑郁症为47.1%。这些比率已经下降到15.8%,26.8%,和34.7%,分别,在2013年。
■这项针对三个严重精神疾病亚组的研究显示,在2000年至2013年之间,在诊断前后,发病率显着增加,就业率下降,突出了及时和正确地进行精神病治疗和职业康复计划的重要性。
UNASSIGNED: The
study aimed to investigate time trends in incidence rates in schizophrenic spectrum disorders (ICD-10: F20-F29), bipolar affective disorder (ICD-10: F30, F31), and recurrent depression (ICD-10: F33) and to investigate the rates of employment for all incident cases.
UNASSIGNED: We used nationwide longitudinal data from 2000 to 2013 on all psychiatric inpatients and outpatients contacts in Denmark. Age-adjusted incidence rate ratios were calculated for the three diagnostic groups, and rates of employment, education, and disability pension were measured 1 year before and 2 years after the diagnosis for all the incident cases.
UNASSIGNED: The incidence rates increased significantly in all diagnostic groups and both sexes. Comparing the incidence rates in 2013 with 2000 yielded an incidence rate ratio of 1.67 (95% CI 1.51-1.84) for schizophrenic spectrum disorders, 3.82 (95% CI 3.23-4.52) for bipolar affective disorder, and 2.80 (95% CI 2.58-3.04) for recurrent depression. During the same observation period, the employment rates decreased, both 1 year before and 2 years after diagnosis in all three subgroups. In the year 2002, employment rates, 2 years after diagnosis, were 24.6% for schizophrenia spectrum disorder, 35.0% for bipolar affective disorder and 47.1% for recurrent depression. These rates had declined to 15.8%, 26.8%, and 34.7%, respectively, in 2013.
UNASSIGNED: This
study of three severe mental illness subgroups shows significant increasing incidence rates and decreasing employment rates both before and after the diagnosis between 2000 and 2013, highlighting the importance of timely and correct volume of the psychiatric treatment and vocational rehabilitation programs.