淋巴上皮瘤样皮肤癌(LELCS)是一种罕见的原发性皮肤癌,年发病率为1/100,000,文献中发表了约85例。它被认为是未分化鼻咽癌的皮肤对应物(UNC,Schmincke-Regaud肿瘤),但与EBV无关。我们提出了一个有趣的案例,在一个93岁的男人身上有LELCS的特征,右额眶区,组织学诊断和免疫组织化学特征。我们还强调对比形态学特征,以正确分类和解决当前问题,提出潜在的见解。最后,我们简要回顾了文献中描述的其他病例.
Lymphoepithelioma-like carcinoma of the skin (LELCS) is a rare primary skin cancer, with an annual incidence of 1/100,000 and about 85 cases published in the literature. It is considered the cutaneous counterpart of undifferentiated nasopharyngeal carcinoma (UNC, Schmincke-Regaud tumor) but has no association with EBV. We present an interesting
case with features of LELCS in a 93-year-old man, right frontal-orbital region, diagnosed histologically and with immunohistochemical features. We also emphasize contrasting morphologic features for correct nosographic classification and address current issues, suggesting potential insights. Finally, we briefly reviewed other cases described in the literature.