背景:睾丸癌是少数即使在转移时也可以治愈的实体癌之一,总生存率超过90%。这项研究的目的是建立年龄调整后的睾丸癌发病率,并严格评估睾丸肿瘤的管理。
方法:这是一项定量的回顾性研究,利用对睾丸睾丸切除术患者的临床记录进行回顾。癌症病例的数量,检查病理类型和癌症分期。
结果:粗发生率和年龄标准化发生率之间没有实质性差异,此外,与苏格兰校际指南报告的粗略发病率没有差异.我们发现55.1%的精原细胞瘤,14.28%的非精原细胞瘤和30.61%的合并(精原细胞瘤和非精原细胞瘤),在61.22%的病例中出现I期疾病,第二阶段36.73%的病例,和IV期占2.04%。大多数癌症在20-50岁年龄段,大多数(48.97%)在31-40岁年龄段。约42.85%的病例被鉴定为高肿瘤标志物;II期精原细胞瘤的百分比更高(40.74%)。
结论:粗发病率和年龄标准化发病率之间没有实质性差异,此外,与报告的粗发病率没有差异。大多数癌症在20-50岁年龄段,大多数(48.97%)在31-40岁年龄段。只有25%的精原细胞瘤的肿瘤标志物升高。此外,加强对IGCCCG预后因子分类的严格适应非常重要.
BACKGROUND: Testicular cancer is one of the few solid cancers that can be cured even when it is metastasized with overall survival rate of more than 90%. The aim of this study was to establish the age adjusted incidence of testicular cancer and to critically assess the management of testicular tumor.
METHODS: This is a quantitative retrospective study utilizing a
review of clinical notes for patients who underwent testicular orchidectomy. The number of cancer cases, types of pathology and cancer staging were examined.
RESULTS: There is no substantial difference between the crude and the age-standardized incidence, moreover no difference from the reported crude incidence by the Scottish intercollegiate guidelines. We found 55.1% of seminoma, 14.28% of non-seminoma and 30.61% of combined (seminoma and non-seminoma), and stage I disease in 61.22% of cases, stage II in 36.73% of cases, and stage IV in 2.04% of cases. Most of the cancers were in the age group 20 - 50 with the majority (48.97%) in the age group 31 - 40. About 42.85% of cases were identified with high tumor markers; higher percentage of seminoma at stage II (40.74%).
CONCLUSIONS: There is no substantial difference between the crude and the age-standardized incidence, moreover no difference from the reported crude incidence. Most of the cancers were in the age group 20 - 50 with the majority (48.97%) in the age group 31 - 40. Only 25% of seminomas had elevated tumor markers. Moreover, it is important to re-enforce strict adaptation to the
IGCCCG prognostic factor-based classifications.