BACKGROUND: In external beam radiotherapy, a prediction model is required to compensate for the temporal system latency that affects the accuracy of radiation dose delivery. This study focused on a thorough comparison of seven deep artificial neural networks to propose an accurate and reliable prediction model.
METHODS: Seven deep predictor models are trained and tested with 800 breathing signals. In this regard, a nonsequential-correlated hyperparameter optimization algorithm is developed to find the best configuration of parameters for all models. The root mean square error (RMSE), mean absolute error, normalized RMSE, and statistical F-test are also used to evaluate network performance.
RESULTS: Overall, tuning the hyperparameters results in a 25%-30% improvement for all models compared to previous studies. The comparison between all models also shows that the gated recurrent unit (GRU) with RMSE = 0.108 ± 0.068 mm predicts respiratory signals with higher accuracy and better performance.
CONCLUSIONS: Overall, tuning the hyperparameters in the GRU model demonstrates a better result than the hybrid predictor model used in the CyberKnife VSI system to compensate for the 115 ms system latency. Additionally, it is demonstrated that the tuned parameters have a significant impact on the prediction accuracy of each model.

The international roughness index (IRI) can be employed to evaluate the smoothness of pavement. The previously proposed mechanical-empirical pavement design guide (MEPDG), which is used to model the IRI of joint plain concrete pavement (JPCP), has been modified in this study considering its disadvantage of low prediction accuracy. To improve the reliability of the prediction effect of the IRI for JPCP, this study compares the prediction accuracy of the IRI of JPCP by using the machine-learning methods of support vector machine (SVM), decision tree (DT), and random forest (RF), optimized by the hyperparameter of the beetle antennae search (BAS) algorithm. The results from the machine-learning process show that the BAS algorithm can effectively improve the effectiveness of hyperparameter tuning, and then improve the speed and accuracy of optimization. The RF model proved to be the one with the highest prediction accuracy among the above three models. Finally, this study analyzes the importance score of input variables to the IRI, and the results show that the IRI was proportional to all the input variables in this study, and the importance score of initial smoothness (IRII) and total joint faulting cumulated per km (TFAULT) were the highest for the IRI of JPCP.