■已经确定了高压氧(HBO)在治疗中暑(HS)动物中的益处。本研究旨在回顾性分析HBO对人类HS后多器官功能障碍的影响。
■收集了过去7年来我院收治的HS患者的回顾性数据。根据患者是否接受HBO治疗进行分组。这项研究比较了各种因素,包括序贯器官衰竭评估(SOFA)和急性生理和慢性健康评估-Ⅱ(APACHE-Ⅱ)评分,死亡率,神经功能评分,血清心肌酶水平,肝脏,肾,和凝血功能指标,血常规结果,电解质水平,治疗前及治疗2周、4周后标准日常生活能力的改良Barthel指数(MBI)评分。
■HBO组和对照组的死亡率分别为0%和8.49%,分别。一被录取,HBO组有较高的SOFA和APACHE-Ⅱ评分和较低的神经,凝血,和肝功能比对照组。HBO治疗显著改善SOFA,APACHE-Ⅱ,和神经系统评分,同时减轻丙氨酸转氨酶水平,天冬氨酸转氨酶,肌酐,和心肌酶。此外,减轻HS引起的淋巴细胞和血小板计数下降。HBO组治疗后MBI评分显著提高。
■临床实践提倡对重症患者进行HBO治疗,器官损伤,和神经损伤。与常规治疗相比,HBO联合治疗在缓解HS患者的多器官功能障碍和改善日常生活能力方面表现出优异的疗效。
UNASSIGNED: The benefits of hyperbaric oxygen (HBO) in treating animals with heat stroke (HS) have been established. This
study aims to retrospectively analyze the effect of HBO on multiple organ dysfunction following HS in humans.
UNASSIGNED: Retrospective data were collected from patients with HS admitted to our hospital in the past 7 years. Patients were categorized into groups based on whether they received HBO therapy. The
study compared various factors, including sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation-Ⅱ (APACHE-Ⅱ) scores, mortality rates, neurological function scores, serum myocardial enzyme levels, liver, kidney, and coagulation function indicators, blood routine results, electrolyte levels, and modified Barthel index (MBI) score for standard daily living ability before treatment and after 2 and 4 weeks of treatment.
UNASSIGNED: The mortality rates in the HBO and control group were 0% and 8.49%, respectively. Upon admission, the HBO group had higher SOFA and APACHE-Ⅱ scores and lower neurological, coagulation, and liver functions than those of the control group. HBO treatment significantly improved SOFA, APACHE-Ⅱ, and neurological scores while relieving levels of alanine aminotransferase, aspartate aminotransferase, creatinine, and myocardial enzymes. Additionally, it mitigating lymphocyte and platelet count decline caused by HS. The MBI score was significantly enhanced after treatment in the HBO group.
UNASSIGNED: Clinical practice advocates administering HBO therapy to patients with severe illness, organ damage, and nerve impairment. Compared with conventional treatment, combined HBO therapy demonstrated superior efficacy in alleviating multiple organ dysfunction and improving daily living ability in patients with HS.