本指南的目的是为医疗保健专业人员提供明确的,关于血栓性血小板减少性紫癜(TTP)和相关血栓性微血管病(TMA)的管理的最新和实用指南,包括补体介导的溶血性尿毒综合征(CMHUS);这些定义为血小板减少症,微血管病性溶血性贫血(MAHA)和小血管血栓形成。在英格兰,所有TTP病例应根据NHSE委托在指定的区域中心进行管理,以提供高度专业化的服务。
The objective of this
guideline is to provide healthcare professionals with clear, up-to-date and practical guidance on the management of thrombotic thrombocytopenic purpura (TTP) and related thrombotic microangiopathies (TMAs), including complement-mediated haemolytic uraemic syndrome (CM
HUS); these are defined by thrombocytopenia, microangiopathic haemolytic anaemia (MAHA) and small vessel thrombosis. Within England, all TTP cases should be managed within designated regional centres as per NHSE commissioning for highly specialised services.