■几种致命疾病的过程和病程，比如癌症，炎症性疾病，和神经系统疾病，与HDAC8密切相关。因此,新型HDAC8抑制剂代表了可能有助于治疗这些疾病的有效治疗可能性.到目前为止，没有任何这种特殊的HDAC8抑制剂可供出售。进行此审查是为了检查最近的HDAC8抑制剂，这些抑制剂在过去十年中获得了专利。
本综述重点介绍了HDAC8抑制剂相关专利及其治疗应用，这些专利在过去十年内已发布，可通过Patentscope和GooglePatents数据库访问。
■在过去的十年中，已经提交了一些与HDAC8抑制剂相关的专利，更具选择性,和特定的HDAC8抑制剂，旨在治疗各种医学疾病。这可能导致开发靶向HDAC8的新型治疗方法。采用理论框架和实验程序可以揭示具有增强的药代动力学特征的新HDAC8抑制剂的产生。彻底了解HDAC8抑制剂在癌症中的作用，包括HDAC8在其他疾病中的作用机制是必要的。
UNASSIGNED: The processes and course of several fatal illnesses, such as cancer, inflammatory diseases, and neurological disorders, are closely correlated with HDAC8. Therefore, novel HDAC8 inhibitors represent effective therapeutic possibilities that may help treat these conditions. To yet, there aren\'t any such particular
HDAC8 inhibitors available for sale. This
review was conducted to examine recent
HDAC8 inhibitors that have been patented over the last ten years.
UNASSIGNED: This
review focuses on
HDAC8 inhibitor-related patents and their therapeutic applications that have been published within the last ten years and are accessible through the Patentscope and Google Patents databases.
UNASSIGNED: A handful of HDAC8 inhibitor-related patents have been submitted over the previous ten years, more selective, and specific HDAC8 inhibitors that are intended to treat a variety of medical diseases. This could lead to the development of novel treatment approaches that target
HDAC8. Employing theoretical frameworks and experimental procedures can reveal the creation of new HDAC8 inhibitors with enhanced pharmacokinetic characteristics. A thorough understanding of the role that HDAC8 inhibitors play in cancer including the mechanisms behind
HDAC8 in other disorders is necessary.
