醋酸环丙孕酮(CPA),羟孕酮衍生物,用于治疗晚期前列腺癌,女性很少出现痤疮,乳腺癌和多毛症。在10-30%的患者中报道了肝酶水平的短暂轻度升高,急性肝衰竭(ALF)并不常见。这里,我们讨论了第一例来自印度的CPA诱导的ALF和现有文献。
Cyproterone acetate (CPA), a hydroxyprogesterone derivative, is used to treat advanced prostate cancer and infrequently in women for acne, breast cancer and hirsutism. Transient mild elevation in levels of liver enzymes is reported in 10-30% of patients, and acute liver failure (ALF) is uncommon. Here, we discuss the first case of CPA-induced ALF from India and the available literature.