Geriatrics

老年病学
  • 文章类型: Case Reports
    此病例报告详细介绍了一名88岁男子的诊断挑战和管理,该男子因败血症样症状出现在日本农村社区医院,根据他的物理和实验室检查结果,最初怀疑是急性细菌性胆管炎。尽管他唑巴坦和哌拉西林的抗生素治疗,病人的症状持续存在,导致进一步的调查显示,没有感染的迹象,但在对比增强的计算机断层扫描中,主动脉弓壁明显增厚。这些发现,结合患者的临床表现和缺乏抗生素反应,将诊断重定向到巨细胞动脉炎(GCA)。每天60mg泼尼松龙的给药可显著缓解症状并防止潜在的严重并发症,例如失明和不可逆的神经损伤。该病例强调了在出现全身炎症症状的老年患者中考虑GCA的重要性以及及时干预的必要性。它还强调了在老年患者中管理高剂量类固醇治疗的挑战,并提出了整合免疫抑制剂以减少类固醇依赖的潜在益处。本报告强调需要在GCA的非典型表现中提高意识和全面的诊断方法,特别是在资源有限的医疗保健环境中的老年人群中。
    This case report details the diagnostic challenge and management of an 88-year-old man who presented to a rural Japanese community hospital with sepsis-like symptoms, initially suspected of acute bacterial cholangitis based on his physical and laboratory findings. Despite the antibiotic treatment of tazobactam and piperacillin, the patient\'s symptoms persisted, leading to further investigations that revealed no signs of infection but notable aortic arch wall thickening on contrast-enhanced computed tomography scans. These findings, combined with the patient\'s clinical presentation and lack of antibiotic response, redirected the diagnosis toward giant cell arteritis (GCA). The administration of prednisolone of 60 mg daily significantly alleviated symptoms and prevented potential severe complications such as blindness and irreversible neurological damage. This case underscores the importance of considering GCA in elderly patients presenting with systemic inflammatory symptoms and the necessity of timely intervention. It also highlights the challenges in managing high-dose steroid therapy in elderly patients and suggests the potential benefits of integrating immunosuppressants to reduce steroid dependency. This report emphasizes the need for heightened awareness and a comprehensive diagnostic approach in atypical presentations of GCA, particularly in geriatric populations within resource-limited healthcare settings.
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  • 文章类型: Case Reports
    营养不良,炎症,共病,和不活动是肌肉减少症的已知原因。它会导致骨折等临床后果,falls,生活质量低,认知功能障碍,和死亡率。特别是在长期固定综合征患者的治疗中,管理不仅应关注功能限制,还应评估和随访患者的肌少症.在这个案例报告中,我们介绍了重症监护病房中可能的尿脓毒血症继发肌少症的治疗方法,并结合文献进行讨论。
    Malnutrition, inflammation, comorbid diseases, and inactivity are known causes of sarcopenia. It results in clinical consequences like fractures, falls, low quality of life, cognitive dysfunction, and mortality. Especially in the treatment of patients with prolonged immobilization syndrome, management should not only focus on functional limitations but patients should also be evaluated and followed up for sarcopenia. In this case report, we present the management of probable secondary sarcopenia in the intensive care unit as a result of urosepsis and discuss it in the light of the literature.
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  • 文章类型: Case Reports
    体温过低定义为核心体温低于35°C。本报告集中于一位向急诊科(ED)就诊的老年人,患有轻度低温,心动过缓,和电解质异常在夏季在温暖的气候。病人是一名82岁男子,被发现体温过低(直肠33.6℃),低血压,和心动过缓。他接受了静脉(IV)液体复苏治疗,主动外部复温(AER),和经验性抗生素治疗他的左下叶肺炎.他被送进重症监护室,并最终通过物理治疗出院。老年人体温过低的风险增加,即使在热带气候。早期认识到体温过低对于取得良好的结果至关重要。
    Hypothermia is defined as a core body temperature of less than 35°C. This report centers on the case of an older adult who presented to the emergency department (ED) with mild hypothermia, bradycardia, and electrolyte abnormalities during the summer in a warm climate. The patient was an 82-year-old man who was found to be hypothermic (33.6°C rectally), hypotensive, and bradycardic. He was treated with intravenous (IV) fluid resuscitation, active external rewarming (AER), and empiric antibiotics for his left lower lobe pneumonia. He was admitted to the intensive care unit and ultimately discharged home with physical therapy. Older adults are at an increased risk for hypothermia, even in a tropical climate. Early recognition of hypothermia is essential to achieve good outcomes.
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  • 文章类型: Journal Article
    This case report details the assessment and interdisciplinary collaboration in the management of an 81-year-old patient presenting with acute visual impairment, dizziness, general weakness, gait disturbances and fear of falling. A holistic geriatric evaluation revealed orthostatic dysregulation and an underlying multifactorial gait disorder exacerbated by visual impairment. Ophthalmological findings included left central retinal artery branch occlusion and cataracts. A comprehensive geriatric assessment showed frailty, impaired mobility and decreased functional abilities. Subsequent patient-centered interdisciplinary approaches included treatment for retinal ischemia, orthostatic testing, medication reconciliation, physiotherapy and occupational therapy. This case emphasizes how interdisciplinary collaboration between ophthalmology and geriatrics enables proactive assessment and intervention to reduce the risk of functional decline and loss of autonomy in visually impaired patients, which is of particular relevance considering the increasing prevalence of visual impairment in the ageing population.
    UNASSIGNED: Dieser Fallbericht beschreibt einen 81-jährigen Patienten, der aufgrund akuter Visusminderung, Schwindel, allgemeiner Schwäche, Gangstörung und Sturzangst in eine Klinik für Augenheilkunde aufgenommen wurde. Zu den ophthalmologischen Befunden gehörten ein reperfundierter Arterienastverschluss links und eine Cataracta corticonuclearis provecta beidseits. Ein umfassendes geriatrisches Assessment ergab zusätzlich geringgradige Frailty, eingeschränkte Mobilität und verringerte Selbsthilfefähigkeit. Die interdisziplinäre Behandlung erfolgte patientenzentriert und umfasste neben der Behandlung und Abklärung der retinalen Ischämie u. a. eine Schwindelabklärung, Medikationsanalyse und -änderung, Physio- sowie Ergotherapie. Sehkraftminderungen gehen bei älteren Menschen mit erhöhtem Risiko für Autonomieverlust, Mobilitätseinschränkung, funktionellen Abbau und verminderter Lebensqualität einher. Das Sturzrisiko und die Mortalität sind erhöht. Dieser Fallbericht verdeutlicht, wie interdisziplinäre Zusammenarbeit zwischen Augenheilkunde und Geriatrie eine frühzeitige Identifikation des individuellen Risikos und geeigneter Interventionen ermöglicht.
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  • 文章类型: Case Reports
    2019年底严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)的出现引起了全球大流行。2019年冠状病毒病(COVID-19)的口腔和皮肤病学表现,如口干症,口疮样病变,溃疡,舌头脱毛,坏死性牙龈炎,和味觉障碍,据报道,包括味觉丧失和唾液腺感染。这项研究旨在描述一例COVID-19感染后口腔溃疡的病例。
    我们介绍了一名95岁男性患者在后续护理和康复病房住院的情况,Minimes老年诊所,图卢兹,法国。在逆转录聚合酶链反应(RT-PCR)检测到COVID-19感染的情况下,他的一般健康状况发生了变化。入院六天后,病人抱怨口腔有强烈的灼烧感,尤其是在舌头和嘴唇粘膜上。口内检查显示舌头的侧边缘和下唇的粘液侧疼痛的糜烂区域。减少灼烧感的拟议治疗基于一般镇痛药(硫酸吗啡),用碳酸氢钠漱口水,以利多卡因为基础的口服麻醉药和愈合凝胶以及舒适饮食的应用。十三天后,患者报告病情逐渐好转.
    在有COVID-19感染史的患者中观察到各种口腔表现。这些口腔溃疡显著影响个体的生活质量,引起剧烈的疼痛,压力,和吃饭的困难,对营养状况有影响,尤其是老年人。我们的案例强调了口腔检查的重要性以及牙医在SARS-CoV-2患者管理中的作用。
    UNASSIGNED: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 caused the global pandemic. Oral and dermatological manifestations of coronavirus disease 2019 (COVID-19) such as xerostomia, aphthous-like lesions, ulcers, tongue depapillation, necrotizing gingivitis, and taste disorders, including the loss of taste and salivary gland infections are being reported. This study aims to describe a case of oral ulcers following COVID-19 infection.
    UNASSIGNED: We present the case of a 95-year-old male patient hospitalized in follow-up care and rehabilitation unit, of Minimes Geriatric Clinic, Toulouse, France. He had an alteration in his general health in the context of COVID-19 infection detected by reverse transcription polymerase chain reaction (RT-PCR). Six days after the admission, the patient complained of a strong burning sensation of the mouth, especially on the tongue and the lips\' mucosa. Intraoral examination revealed painful erosive areas on the lateral edges of the tongue and the mucous side of the lower lip. The proposed treatment to reduce the burning sensation was based on general analgesics (morphine sulfate), mouthwash with sodium bicarbonate, the application of a lidocaine-based oral anesthetic and healing gel and a comfort-oriented diet. Thirteen days later, the patient reported a gradual improvement.
    UNASSIGNED: A diverse range of oral manifestations has been observed in patients with a history of COVID-19 infection. These oral ulcers significantly impact the quality of life of the individual, causing intense pain, stress, and difficulties in eating, with repercussions on nutritional status, especially in older individuals. Our case underscores the importance of oral examinations and the role of dentists in the management of patients with SARS-CoV-2.
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  • 文章类型: Journal Article
    目标:为退伍军人事务部(VA)计划STRIDE(为住院的老年人提供Early移动服务)进行商业案例分析,旨在解决住院老年人的不动问题。
    方法:这是对功能和独立性质量增强研究计划(QUERI)进行的VA8医院实施试验的主要数据的二次分析。与VA运营合作伙伴合作,我们估计了在VA内外实施计划所需的资源以及VA的国家实施便利化。使用劳工统计局的工资数据进行的情景分析可告知VA以外的实施决策。
    方法:本预算影响分析比较了两种实施策略(复制有效计划[REP]+CONNECT和仅REP)的交付和实施成本。为了模拟国家预算方案的实施,我们估计了全国符合条件的住院次数和各种关键参数(例如,入学率)来评估不确定性的影响。
    方法:从医院收集人员时间和实施结果(2017-2019年)。截至2022年,估计了医院平均每日人口普查和工资数据,以提高与未来实施的相关性。
    结果:REP+CONNECT的平均实施成本为9450美元,仅REP的平均实施成本为5622美元;在VA和非VA医院环境中,每位参与者的平均计划交付成本均低于30美元。步行次数对交付成本的影响最大,每位参与者步行1至5次。在敏感性分析中,如果物理治疗师助理进行步行,每个参与者的费用增加到35美元。在研究医院中,REP+CONNECT医院(12%)的平均入组率高于仅REP医院(4%),VA实施费用为每例入组66~100美元.
    结论:STRIDE是一种低成本的干预措施,项目参与对交付STRIDE所需的资源影响最大。
    背景:ClinicalsTrials.govNCT03300336。预计于2017年10月3日注册。
    OBJECTIVE: To conduct a business case analysis for Department of Veterans Affairs (VA) program STRIDE (ASsisTed EaRly MobIlization for hospitalizeD older VEterans), which was designed to address immobility for hospitalized older adults.
    METHODS: This was a secondary analysis of primary data from a VA 8-hospital implementation trial conducted by the Function and Independence Quality Enhancement Research Initiative (QUERI). In partnership with VA operational partners, we estimated resources needed for program delivery in and out of the VA as well as national implementation facilitation in the VA. A scenario analysis using wage data from the Bureau of Labor Statistics informs implementation decisions outside the VA.
    METHODS: This budget impact analysis compared delivery and implementation costs for two implementation strategies (Replicating Effective Programs [REP]+CONNECT and REP-only). To simulate national budget scenarios for implementation, we estimated the number of eligible hospitalizations nationally and varied key parameters (e.g., enrollment rates) to evaluate the impact of uncertainty.
    METHODS: Personnel time and implementation outcomes were collected from hospitals (2017-2019). Hospital average daily census and wage data were estimated as of 2022 to improve relevance to future implementation.
    RESULTS: Average implementation costs were $9450 for REP+CONNECT and $5622 for REP-only; average program delivery costs were less than $30 per participant in both VA and non-VA hospital settings. Number of walks had the most impact on delivery costs and ranged from 1 to 5 walks per participant. In sensitivity analyses, cost increased to $35 per participant if a physical therapist assistant conducts the walks. Among study hospitals, mean enrollment rates were higher among the REP+CONNECT hospitals (12%) than the REP-only hospitals (4%) and VA implementation costs ranged from $66 to $100 per enrolled.
    CONCLUSIONS: STRIDE is a low-cost intervention, and program participation has the biggest impact on the resources needed for delivering STRIDE.
    BACKGROUND: ClinicalsTrials.gov NCT03300336. Prospectively registered on 3 October 2017.
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  • 文章类型: Journal Article
    目的:在药学教育中,发展与老年人护理相关的能力是必要的。技能实验室作为课程的重要组成部分,代表了教授老年医学的重要环境。这项研究的目的是描述本科药学课程的技能/模拟活动中的老年医学案例。
    方法:对蒙特利尔大学药学院药学项目一学年的技能实验室进行了回顾性回顾。选择包括年龄≥65岁的病例在内的会议。内容提取了与患者相关的特征,健康,药物,和关心背景。一个框架,包括老年考虑,如老年综合征,脆弱状态,并为数据收集开发了可能不合适的药物。
    结果:总计,抽取210例患者病例。老年人(≥65岁)占51例(24%),年龄≥80岁8例(4%)。老年综合征记录为8%,10%的功能状态,和流动性在12%的情况下。合并症和药物治疗的中位数分别为4和7。关于多药房,只有10例患者服用了>10种药物,没有超过15种药物。在47%(n=24)的病例中发现了潜在的不适当药物,但仅在14%(n=7)的病例中得到了解决。
    结论:这种技能实验室图突出了老年医学内容的差距。少数病例中纳入了年龄最大的患者和老年病学问题,并且缺乏老年病学护理所必需的许多特征。
    Development of competencies related to care of older adults is necessary in pharmacy education. Skills laboratories as an essential part of the curriculum represent an important setting to teach geriatrics. The purpose of this research was to describe geriatrics cases in skills/simulation activities of an undergraduate pharmacy program.
    A retrospective review of one academic year of skills laboratories from the pharmacy program at the Faculty of Pharmacy of University of Montreal was performed. Sessions including cases aged ≥65 years were selected. Content was extracted for characteristics relating to the patient, health, medications, and care context. A framework including geriatric considerations such as geriatric syndromes, frailty status, and potentially inappropriate medications was developed for data collection.
    In total, 210 patient cases were extracted. Older adults (≥ 65 years) were represented in 51 cases (24%), with 8 cases (4%) aged ≥80 years. Geriatric syndromes were documented in 8%, functional status in 10%, and mobility in 12% of the cases. The median number of comorbidities and medications were 4 and 7, respectively. Regarding polypharmacy, only 10 cases had >10 medications, and none had >15 medications. Potentially inappropriate medications were found in 47% (n = 24) of the cases but were addressed in only 14% (n = 7) cases.
    This mapping of skills laboratories highlights gaps in geriatrics content. Inclusion of the oldest patients and geriatrics issues were incorporated in a minority of cases and lacked many characteristics essential for geriatrics care.
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  • 文章类型: Journal Article
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  • 文章类型: Editorial
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  • 文章类型: Case Reports
    该病例报告描述了一名86岁的女性患者,该患者在股骨颈骨折的骨科手术后出现了复杂的术后并发症。最初诊断为脓毒性休克由于耐甲氧西林金黄色葡萄球菌(MRSA)菌血症在手术部位,病人的治疗过程很复杂,涉及多次医院转移和不同的治疗方法,包括抗生素和手术引流.尽管治疗后没有感染指标,患者后来出现严重的大腿疼痛,并被发现有迁徙性假性痛风,在MRSA和术后并发症的情况下的异常诊断。本报告强调了在区分手术部位感染和其他炎症性疾病(如迁徙性假痛风)方面的诊断挑战。特别是在有合并症的老年患者中。它强调了全面评估的重要性,以及普通医师在管理手术后感染时保持广泛鉴别诊断的必要性。该病例突出了MRSA感染的持久性和复发风险,即使是适当的抗生素治疗后,以及在反复感染和全身软组织受累的患者中考虑迁移假性的必要性。该病例的见解有助于理解复杂的术后并发症,并倡导在类似的临床情况下进行细致的评估和量身定制的治疗策略。
    This case report describes an 86-year-old female patient who presented with complex post-surgical complications following orthopedic surgery for a femoral neck fracture. Initially diagnosed with septic shock due to methicillin-resistant Staphylococcus aureus (MRSA) bacteremia at the surgical site, the patient\'s treatment course was complicated, involving multiple hospital transfers and varying treatments, including antibiotics and surgical drainage. Despite the absence of infection indicators post treatment, the patient later developed severe thigh pain and was found to have migratory pseudogout, an unusual diagnosis in the context of MRSA and post-surgical complications. This report emphasizes the diagnostic challenges in distinguishing between surgical site infections and other inflammatory conditions like migratory pseudogout, particularly in older patients with comorbidities. It underscores the importance of comprehensive evaluations and the need for general physicians to maintain a broad differential diagnosis when managing post-surgical infections. The case highlights the persistence and recurrence risk of MRSA infections, even post-appropriate antibiotic therapy, and the necessity of considering migratory pseudogout in patients with recurrent infections and systemic soft tissue involvement. The insights from this case contribute to the understanding of complex post-surgical complications and advocate for meticulous assessment and tailored treatment strategies in similar clinical scenarios.
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