Gastric bypass

胃旁路
  • 文章类型: Journal Article
    背景:食管裂孔疝(HH)是一种常见病。召集了一个多学科专家小组,以制定基于证据的建议,以支持临床医生,病人,和其他人在关于HH治疗的决定中。
    方法:针对成人HH治疗的四个关键问题进行了系统评价:无症状HH的手术治疗与监测;使用网状物与不使用网状物;进行胃底折叠术与不进行胃底折叠术;以及Roux-en-Y胃旁路术(RYGB)与重复胃底折叠术治疗复发性HH。循证建议是使用建议分级制定的,评估,发展,和主题专家的评估方法。当证据不足以提出建议时,专家意见被用来代替。还提出了未来研究的建议。
    结果:专家组为患有HH的成年人提供了一项有条件的建议和两项专家意见。小组建议在HH修复中常规进行胃底折叠术,尽管这是基于低确定性的证据。关于手术修复无症状HH或复发性HH转换为RYGB的证据不足,因此,只提供专家意见。小组建议选择无症状的患者可以接受手术修复,与标准概述。同样,它提示在某些患者中转换为RYGB治疗复发性HH可能是合适的,并再次描述了标准.在HH修复中常规使用网格的证据是模棱两可的,因此专家组推迟了建议。
    结论:这些建议应该为HH治疗的手术决策提供指导,并强调共同决策和考虑患者价值以优化结果的重要性。追求已确定的研究需求将改善证据基础,并可能在未来基于证据的HH治疗指南中提出更强有力的建议。
    BACKGROUND: Hiatal hernia (HH) is a common condition. A multidisciplinary expert panel was convened to develop evidence-based recommendations to support clinicians, patients, and others in decisions regarding the treatment of HH.
    METHODS: Systematic reviews were conducted for four key questions regarding the treatment of HH in adults: surgical treatment of asymptomatic HH versus surveillance; use of mesh versus no mesh; performing a fundoplication versus no fundoplication; and Roux-en-Y gastric bypass (RYGB) versus redo fundoplication for recurrent HH. Evidence-based recommendations were formulated using the Grading of Recommendations, Assessment, Development, and Evaluations methodology by subject experts. When the evidence was insufficient to base recommendations on, expert opinion was utilized instead. Recommendations for future research were also proposed.
    RESULTS: The panel provided one conditional recommendation and two expert opinions for adults with HH. The panel suggested routinely performing a fundoplication in the repair of HH, though this was based on low certainty evidence. There was insufficient evidence to make evidence-based recommendations regarding surgical repair of asymptomatic HH or conversion to RYGB in recurrent HH, and therefore, only expert opinions were offered. The panel suggested that select asymptomatic patients may be offered surgical repair, with criteria outlined. Similarly, it suggested that conversion to RYGB for management of recurrent HH may be appropriate in certain patients and again described criteria. The evidence for the routine use of mesh in HH repair was equivocal and the panel deferred making a recommendation.
    CONCLUSIONS: These recommendations should provide guidance regarding surgical decision-making in the treatment of HH and highlight the importance of shared decision-making and consideration of patient values to optimize outcomes. Pursuing the identified research needs will improve the evidence base and may allow for stronger recommendations in future evidence-based guidelines for the treatment of HH.
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  • 文章类型: Journal Article
    目的:缺乏治疗某些疾病的证据,包括并发症处理,初始体重减轻次优,经常性的体重增加,或一次吻合胃旁路术(OAGB)后严重肥胖并发症恶化。这项研究旨在通过采用专家修改的德尔菲共识方法来应对现有的缺乏共识,并为临床医生提供宝贵的资源。
    方法:来自28个国家的48名公认的减肥外科医生参加了改良的德尔菲共识,在两轮中对64项声明进行了投票。≥70.0%的专家之间的同意/分歧被认为表明共识。
    结果:对46个陈述达成共识。对于OAGB后复发性体重增加或严重肥胖并发症的恶化,超过85%的专家达成共识,认为延长胆胰肢(BPL)是一种可接受的选择,并且在延长BPL期间必须进行总肠长度测量,以保留至少300~400cm的共同通道肢体长度,以避免营养缺乏.此外,超过85%的专家就转换为Roux-en-Y胃旁路术(RYGB)(无论是否缩小囊袋)作为OAGB术后持续性胆汁反流的可接受治疗方案达成共识,并建议在转换为RYGB期间检测和修复任何大小的食管裂孔疝.
    结论:虽然专家们就OAGB后的修订/转换手术的几个方面达成了共识,仍然存在挥之不去的分歧。这突出了今后进行进一步研究以解决这些悬而未决的问题的重要性。
    OBJECTIVE: There is a lack of evidence for treatment of some conditions including complication management, suboptimal initial weight loss, recurrent weight gain, or worsening of a significant obesity complication after one anastomosis gastric bypass (OAGB). This study was designed to respond to the existing lack of agreement and to provide a valuable resource for clinicians by employing an expert-modified Delphi consensus method.
    METHODS: Forty-eight recognized bariatric surgeons from 28 countries participated in the modified Delphi consensus to vote on 64 statements in two rounds. An agreement/disagreement among ≥ 70.0% of the experts was regarded to indicate a consensus.
    RESULTS: A consensus was achieved for 46 statements. For recurrent weight gain or worsening of a significant obesity complication after OAGB, more than 85% of experts reached a consensus that elongation of the biliopancreatic limb (BPL) is an acceptable option and the total bowel length measurement is mandatory during BPL elongation to preserve at least 300-400 cm of common channel limb length to avoid nutritional deficiencies. Also, more than 85% of experts reached a consensus on conversion to Roux-en-Y gastric bypass (RYGB) with or without pouch downsizing as an acceptable option for the treatment of persistent bile reflux after OAGB and recommend detecting and repairing any size of hiatal hernia during conversion to RYGB.
    CONCLUSIONS: While the experts reached a consensus on several aspects regarding revision/conversion surgeries after OAGB, there are still lingering areas of disagreement. This highlights the importance of conducting further studies in the future to address these unresolved issues.
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  • 文章类型: English Abstract
    Until now, there has not been organized consensus for standardization in bariatric surgery In Russia. We present the results of the first Bariatric Surgery Consensus Conference conducted in Barnaul (March, 2023). A list of questions was proposed within 6 blocks: 1) general issues of bariatric surgery, 2) sleeve gastrectomy, 3) one-anastomosis gastric bypass («mini-gastric bypass»), 4) Roux-en-Y Gastric Bypass, 5) Single Anastomosis Duodenal Switch and other options for biliopancreatic bypass, 6) rare procedures. Consensus (>70% agreement) was reached for 51 out of 96 statements. Stratification by the level of expertise was carried out, and responses of the expert group were compared with responses of all participants.
    До настоящего времени в России не проводилось согласования относительно проблем стандартизации в бариатрической хирургии. В данной публикации представлены результаты первой Консенсус-конференции по бариатрической хирургии. Был предложен перечень вопросов в рамках 6 блоков: 1) общие вопросы бариатрической хирургии; 2) продольная резекция желудка; 3) одноанастомозное желудочное («минижелудочное») шунтирование; 4) шунтирование по Ру; 5) SADI и другие варианты билиопанкреатического шунтирования; 6) редко выполняемые бариатрические операции. Консенсус считался достигнутым при наличии 70% голосов. Консенсус был достигнут по 51 из 96 вопросам. Проведена стратификация по уровню экспертности и осуществлено сравнение ответов группы экспертов с ответами всех участников голосования.
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  • 文章类型: Journal Article
    代谢和减肥手术(MBS)被广泛认为是治疗肥胖的最有效选择。一个慢性的,复发,和进行性疾病。最近,美国代谢和减肥外科学会(ASMBS)和国际肥胖和代谢紊乱外科联合会(IFSO)发布了关于MBS适应症的新指南,它取代了以前的1991年美国国立卫生研究院指南。这项研究的目的是建立第一套共识指南,以选择I类和II类肥胖的程序。使用专家改进的德尔菲法。在这项研究中,来自32个国家/地区的78名经验丰富的减肥外科医师参加了两轮改良Delphi共识投票过程。专家之间的共识阈值设定为≥70.0%的共识或分歧。专家们就54项声明达成共识。专家委员会达成共识,认为MBS是II类肥胖和通过非手术方法未实现明显体重减轻的I类肥胖患者的具有成本效益的治疗选择。MBS也被认为适用于2型糖尿病(T2DM)和体重指数(BMI)为30kg/m2或更高的患者。委员会将胃内球囊(IGB)确定为I类肥胖患者的治疗选择,将内窥镜套筒胃成形术(ESG)确定为I类和II类肥胖患者的治疗选择,以及BMI≥30kg/m2的T2DM患者。袖状胃切除术(1)和Roux-en-Y胃旁路术(RYGB)也被认为是这些患者组的可行治疗选择。委员会还同意,对于II类肥胖和T2DM患者,一次吻合胃旁路术(OAGB)是一个合适的选择。无论肥胖相关医疗问题的存在或严重程度。选择I类和II类肥胖程序的建议,通过专家修改的德尔菲共识开发,建议使用标准的原发性减肥内镜(IGB,ESG)和外科手术(SG,RYGB,OAGB)在这些患者群体中是可以接受的,就这些程序达成共识。然而,对于I类和II类肥胖患者,仍需要进行随机对照试验,以确定未来这些患者的最佳治疗方法.
    Metabolic and bariatric surgery (MBS) is widely considered the most effective option for treating obesity, a chronic, relapsing, and progressive disease. Recently, the American Society of Metabolic and Bariatric Surgery (ASMBS) and the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) issued new guidelines on the indications for MBS, which have superseded the previous 1991 National Institutes of Health guidelines. The aim of this study is to establish the first set of consensus guidelines for selecting procedures in Class I and II obesity, using an Expert Modified Delphi Method. In this study, 78 experienced bariatric surgeons from 32 countries participated in a two-round Modified Delphi consensus voting process. The threshold for consensus was set at an agreement or disagreement of ≥ 70.0% among the experts. The experts reached a consensus on 54 statements. The committee of experts reached a consensus that MBS is a cost-effective treatment option for Class II obesity and for patients with Class I obesity who have not achieved significant weight loss through non-surgical methods. MBS was also considered suitable for patients with Type 2 diabetes mellitus (T2DM) and a body mass index (BMI) of 30 kg/m2 or higher. The committee identified intra-gastric balloon (IGB) as a treatment option for patients with class I obesity and endoscopic sleeve gastroplasty (ESG) as an option for patients with class I and II obesity, as well as for patients with T2DM and a BMI of ≥ 30 kg/m2. Sleeve gastrectomy (1) and Roux-en-Y gastric bypass (RYGB) were also recognized as viable treatment options for these patient groups. The committee also agreed that one anastomosis gastric bypass (OAGB) is a suitable option for patients with Class II obesity and T2DM, regardless of the presence or severity of obesity-related medical problems. The recommendations for selecting procedures in Class I and II obesity, developed through an Expert Modified Delphi Consensus, suggest that the use of standard primary bariatric endoscopic (IGB, ESG) and surgical procedures (SG, RYGB, OAGB) are acceptable in these patient groups, as consensus was reached regarding these procedures. However, randomized controlled trials are still needed in Class I and II Obesity to identify the best treatment approach for these patients in the future.
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  • 文章类型: Journal Article
    背景:这项针对国际肥胖管理专家的调查旨在就标准化定义达成共识,并确定代谢减肥手术(MBS)中的共识和非共识领域,以帮助制定肥胖管理的临床实践指南。
    方法:由包括26名减肥外科医生在内的43名肥胖管理专家进行了一项包含136个陈述的三轮德尔菲调查,4位内窥镜医师,8位内分泌学家,2位营养学家,2名顾问,内科医生,一位横跨六大洲的儿科医生在汉堡举行了为期两天的会议,德国。为了减少偏见,投票是一致的,声明对投票的问题既不有利也不不利,或者在有利和不利之间均衡。共识被定义为≥70%的选民间协议。
    结果:就所有15个基本定义和报告声明达成共识,包括最初的次优临床反应,基线重量,经常性的体重增加,转换,和翻修手术。关于有利于Roux-en-Y胃旁路手术的外科手术类型的95/121声明达成共识,袖状胃切除术,和内镜下套管胃成形术。袖状胃切除术单吻合十二指肠回肠造口术达成了中度共识,而对胃内球囊的作用则没有达成共识。MBS在65岁以上和18岁以下的患者中达成共识,BMI>50kg/m2,并伴有各种肥胖相关并发症,如2型糖尿病,肝脏,和肾脏疾病。
    结论:在对43名多学科专家的调查中,就适用于整个医学界的标准化定义和报告标准达成共识.利用周到的多模式方法探索了一种治疗肥胖患者的算法。
    BACKGROUND: This survey of international experts in obesity management was conducted to achieve consensus on standardized definitions and to identify areas of consensus and non-consensus in metabolic bariatric surgery (MBS) to assist in an algorithm of clinical practice guidelines for the management of obesity.
    METHODS: A three-round Delphi survey with 136 statements was conducted by 43 experts in obesity management comprising 26 bariatric surgeons, 4 endoscopists, 8 endocrinologists, 2 nutritionists, 2 counsellors, an internist, and a pediatrician spanning six continents over a 2-day meeting in Hamburg, Germany. To reduce bias, voting was unanimous, and the statements were neither favorable nor unfavorable to the issue voted or evenly balanced between favorable and unfavorable. Consensus was defined as ≥ 70% inter-voter agreement.
    RESULTS: Consensus was reached on all 15 essential definitional and reporting statements, including initial suboptimal clinical response, baseline weight, recurrent weight gain, conversion, and revision surgery. Consensus was reached on 95/121 statements on the type of surgical procedures favoring Roux-en-Y gastric bypass, sleeve gastrectomy, and endoscopic sleeve gastroplasty. Moderate consensus was reached for sleeve gastrectomy single-anastomosis duodenoileostomy and none on the role of intra-gastric balloons. Consensus was reached for MBS in patients > 65 and < 18 years old, with a BMI > 50 kg/m2, and with various obesity-related complications such as type 2 diabetes, liver, and kidney disease.
    CONCLUSIONS: In this survey of 43 multi-disciplinary experts, consensus was reached on standardized definitions and reporting standards applicable to the whole medical community. An algorithm for treating patients with obesity was explored utilizing a thoughtful multimodal approach.
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  • 文章类型: Journal Article
    只有在美国,每年花费3150亿美元用于成年患者肥胖的医疗费用。到现在为止,减重手术是治疗肥胖最有效的方法,可以在降低肥胖治疗的直接和间接成本方面发挥重要作用。尽管如此,很少有包括营养在内的综合指南,身体活动,和补充,手术前后。本叙述性审查的目的是提供更新和全面的实用指南,以帮助多学科团队。核心关键词包括营养,饮食,身体活动,锻炼,补充剂,大量营养素,微量营养素,减轻体重,减肥手术,Roux-en-Y胃旁路术,袖状胃造口术,腹腔镜可调节胃带,和十二指肠开关的胆道胰腺转移,在包括PubMed/Medline在内的数据库中进行了搜索,科克伦,和其他一些来源,如谷歌学者。我们回答了五个重要领域的问题:(a)减肥手术前的营养策略,(b)减肥手术后的营养,(c)减肥手术前后的身体活动,(d)减肥手术后体重恢复,和(e)减肥手术前后的微量营养素评估和建议。在此更新的指南中增加了一些新项目,包括“体重恢复”和“减肥手术后怀孕”。“其他字段根据新的证据和指南进行了更新。
    Only in the USA, 315 billion dollars are spent annually on the medical cost of obesity in adult patients. Till now, bariatric surgery is the most effective method for treating obesity and can play an essential role in reducing the direct and indirect costs of obesity treatment. Nonetheless, there are few comprehensive guidelines which include nutrition, physical activity, and supplements, before and after surgery. The purpose of the present narrative review is to provide an updated and comprehensive practical guideline to help multidisciplinary teams. The core keywords include nutrition, diet, physical activity, exercise, supplements, macronutrients, micronutrients, weight reduction, bariatric surgery, Roux-en-Y Gastric Bypass, Sleeve Gastrostomy, Laparoscopic Adjustable Gastric Banding, and Biliopancreatic diversion with duodenal switch which were searched in databases including PubMed/Medline, Cochrane, and some other sources such as Google Scholar. We answered questions in five important areas: (a) nutritional strategies before bariatric surgery, (b) nutrition after bariatric surgery, (c) physical activity before and after bariatric surgery, (d) weight regain after bariatric surgery, and (e) micronutrient assessments and recommendations before and after bariatric surgery. Some new items were added in this updated guideline including \"weight regain\" and \"pregnancy after bariatric surgery.\" Other fields were updated based on new evidence and guidelines.
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  • 文章类型: Journal Article
    背景:减肥手术患者对营养缺乏的预防建议的长期依从性通常较差,但尚不清楚哪些因素会导致营养缺乏。我们调查了年龄的关联,性别,和社会经济地位(SES),并遵守有关蛋白质摄入和微量营养素补充的指南建议。
    方法:在一项单中心的横断面研究中,我们前瞻性地招募了接受袖状胃切除术(SG)或Roux-en-Y胃旁路术(RYGB)的患者,术后最短时间为6个月。临床和人口统计学数据来自患者的医疗档案和问卷调查。患者报告了补充剂的使用情况,记录他们七天的饮食摄入量,并接受身体检查,包括血液测试。
    结果:我们纳入了35例患者(SG:n=25,RYGB:n=10),术后平均(±SD)时间为20.2(±10.4)个月。年龄分布,SG组和RYGB组的性别和SES具有可比性.不遵守推荐的蛋白质摄入量与年龄≥50岁(p=0.041)有关,但与性别或SES无关。蛋白质摄入与肥胖标志物呈负相关。年龄或性别与微量营养素补充剂没有显着关联。仅对于维生素A(p=0.049)和B1(p=0.047),较高的SES与较高的依从性相关。与不坚持补充微量营养素有关的唯一明显缺陷是叶酸(p=0.044)。
    结论:减肥手术后的患者,年龄较大且SES较低的人群可能有更大的不良结局风险,可能需要更多地关注微量营养素和蛋白质的补充.
    BACKGROUND: Patients with bariatric surgery often show poor long-term compliance to recommendations for prevention of nutrient deficiency but it is unclear which factors contribute. We investigated the associations of age, sex, and socioeconomic status (SES) with adherence to guideline recommendations on protein intake and micronutrient supplementation.
    METHODS: In a monocentric cross-sectional study we prospectively recruited patients with sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) and a minimum postoperative period of 6 months. Clinical and demographic data were obtained from the patients\' medical files and by questionnaire. Patients reported on supplement usage, recorded their dietary intake for seven days and underwent physical examinations including blood testing.
    RESULTS: We included 35 patients (SG: n = 25, RYGB: n = 10) with a mean (+SD) postoperative period of 20.2 (±10.4) months. Distributions of age, sex and SES were comparable between the SG and RYGB groups. Non-adherence to recommended protein intake was associated with age ≥ 50 years (p = 0.041) but not sex or SES. Protein intake inversely correlated with markers of obesity. There were no significant associations of age or sex with micronutrient supplementation. Only for vitamins A (p = 0.049) and B1 (p = 0.047) higher SES was associated with greater compliance. The only manifest deficiency associated with non-adherence to micronutrient supplementation was that for folic acid (p = 0.044).
    CONCLUSIONS: In patients after bariatric surgery, those of older age and of lower SES might have a greater risk of unfavorable outcome and may require greater attention to micronutrient and protein supplementation.
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  • 文章类型: Journal Article
    背景:袖状胃切除术(SG)是全球最常见的代谢和减肥手术(MBS)程序。尽管SG对体重减轻和缓解肥胖相关的医疗问题有预期的效果,对于SG后进行修改/转换手术的必要性,存在一些担忧。本研究旨在根据专家修改的Delphi共识制定算法临床方法,为减肥和代谢外科医生提供可能有助于最佳临床决策的指南。
    方法:来自25个不同国家的46名公认的减肥和代谢外科医生分两轮参与了这项Delphi共识研究,以就SG后的重做手术达成共识。关于声明的同意/分歧≥70.0%被认为表明达成共识。
    结果:在经过两轮在线投票后,72份声明中有62份达成了共识,专家们对10份声明没有达成共识。大多数专家认为,应在SG后的所有重做程序中进行多学科团队评估,并且在SG后进行重做手术之前,应至少进行12个月的医疗和支持管理,以减少体重。体重恢复,胃食管反流病(GERD)。此外,专家们一致认为,如果有症状的GERD存在足够的体重减轻,至少1~2年的药物治疗是一种可接受的选择,并同意Roux-enY胃旁路术是这种情况下的适当选择.在存在扩张的眼底和GERD的情况下,对大网膜固定术在旋转中的疗效和胃底折叠术的疗效存在分歧。
    结论:SG后的重做手术仍然是减肥和代谢外科医生的重要问题。重做手术的适当时间和程序选择需要仔细考虑。尽管多学科团队评估在评估这些情况下的最佳选择方面起着关键作用,以专家共识为指导的算法临床方法有助于制定最佳的临床决策.
    Sleeve gastrectomy (SG) is the most common metabolic and bariatric surgical (MBS) procedure worldwide. Despite the desired effect of SG on weight loss and remission of obesity-associated medical problems, there are some concerns regarding the need to do revisional/conversional surgeries after SG. This study aims to make an algorithmic clinical approach based on an expert-modified Delphi consensus regarding redo-surgeries after SG, to give bariatric and metabolic surgeons a guideline that might help for the best clinical decision.
    Forty-six recognized bariatric and metabolic surgeons from 25 different countries participated in this Delphi consensus study in two rounds to develop a consensus on redo-surgeries after SG. An agreement/disagreement ≥ 70.0% on statements was considered to indicate a consensus.
    Consensus was reached for 62 of 72 statements and experts did not achieve consensus on 10 statements after two rounds of online voting. Most of the experts believed that multi-disciplinary team evaluation should be done in all redo-procedures after SG and there should be at least 12 months of medical and supportive management before performing redo-surgeries after SG for insufficient weight loss, weight regain, and gastroesophageal reflux disease (GERD). Also, experts agreed that in case of symptomatic GERD in the presence of adequate weight loss, medical treatment for at least 1 to 2 years is an acceptable option and agreed that Roux-en Y gastric bypass is an appropriate option in this situation. There was disagreement consensus on efficacy of omentopexy in rotation and efficacy of fundoplication in the presence of a dilated fundus and GERD.
    Redo-surgeries after SG is still an important issue among bariatric and metabolic surgeons. The proper time and procedure selection for redo-surgery need careful considerations. Although multi-disciplinary team evaluation plays a key role to evaluate best options in these situations, an algorithmic clinical approach based on the expert\'s consensus as a guideline can help for the best clinical decision-making.
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  • 文章类型: Journal Article
    背景:胃食管反流病(GERD)是北美和全球最常见的疾病之一。本指南的目的是提供有关GERD的最常用和可用的内窥镜和手术治疗的循证建议。
    方法:针对成人GERD手术和内镜治疗的4个关键问题进行了系统的文献综述:术前评估,内窥镜与手术或药物治疗,完全胃底折叠术与部分胃底折叠术,以及肥胖(体重指数[BMI]≥35kg/m2)和合并GERD的治疗。主题专家使用GRADE方法制定了基于证据的建议。还提出了未来研究的建议。
    结果:共识提供了13条建议。通过制定这些循证建议,提出了一种辅助治疗GERD的算法.有典型症状的患者应接受上消化道内窥镜检查,测压,和pH值测试;对于不典型或食道外症状的患者,可能需要额外的测试。测压正常或异常的患者应考虑接受部分胃底折叠术。对于患有GERD的成年人,磁性括约肌增强或胃底折叠术是合适的外科手术。对于希望避免手术的患者,研究发现,Stretta手术和经口无切口胃底折叠术(TIF2.0)的结局优于单用质子泵抑制剂.建议合并肥胖的患者接受胃旁路术或胃底折叠术,尽管患有严重合并症或BMI>50的患者应接受Roux-en-Y胃旁路术,以获得体重减轻后的额外益处.
    结论:使用建议,该小组开发了一种算法,以便医生可以更好地为GERD患者提供建议。某些患者因素已被排除在纳入的研究/试验之外,因此,这些建议不应取代外科医生-患者的决策。参与确定的研究领域可能会改善GERD患者的未来护理。
    Gastroesophageal reflux disease (GERD) is one of the most common diseases in North America and globally. The aim of this guideline is to provide evidence-based recommendations regarding the most utilized and available endoscopic and surgical treatments for GERD.
    Systematic literature reviews were conducted for 4 key questions regarding the surgical and endoscopic treatments for GERD in adults: preoperative evaluation, endoscopic vs surgical or medical treatment, complete vs partial fundoplication, and treatment for obesity (body mass index [BMI] ≥ 35 kg/m2) and concomitant GERD. Evidence-based recommendations were formulated using the GRADE methodology by subject experts. Recommendations for future research were also proposed.
    The consensus provided 13 recommendations. Through the development of these evidence-based recommendations, an algorithm was proposed for aid in the treatment of GERD. Patients with typical symptoms should undergo upper endoscopy, manometry, and pH-testing; additional testing may be required for patients with atypical or extra-esophageal symptoms. Patients with normal or abnormal findings on manometry should consider undergoing partial fundoplication. Magnetic sphincter augmentation or fundoplication are appropriate surgical procedures for adults with GERD. For patients who wish to avoid surgery, the Stretta procedure and transoral incisionless fundoplication (TIF 2.0) were found to have better outcomes than proton pump inhibitors alone. Patients with concomitant obesity were recommended to undergo either gastric bypass or fundoplication, although patients with severe comorbid disease or BMI > 50 should undergo Roux-en-Y gastric bypass for the additional benefits that follow weight loss.
    Using the recommendations an algorithm was developed by this panel, so that physicians may better counsel their patients with GERD. There are certain patient factors that have been excluded from included studies/trials, and so these recommendations should not replace surgeon-patient decision making. Engaging in the identified research areas may improve future care for GERD patients.
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  • 文章类型: Journal Article
    The quantity of cases of metabolic and obesity-related diseases including obesity and type 2 diabetes in China are increasing each year. The total numbers of both existing patients and new patients each year are rated as the highest in the world. A large amount of evidence-based medical reports have shown that bariatric surgery can effectively reduce excessive body weight in patients with morbid obesity, and alleviate the effects of a series of obesity-related metabolic comorbidities, including type 2 diabetes. Laparoscopic one anastomosis gastric bypass (OAGB) is currently one of the most widely practiced bariatric surgeries procedures in the world. Although this procedure has been carried out on patients in China for more than 15 years, the standard surgical operation for OAGB has not been subject to relevant guidelines or consensus. In light of this, Chinese Society for Metabolic & Bariatric Surgery (CSMBS) recently initiated the compilation of the first edition of the \"Procedural guideline for laparoscopic one anastomosis gastric bypass (2022 Edition)\", aiming to provide a unified specifications for this procedure. It will provide a reference for surgical operating standards for clinicians in the field of obesity-related metabolic surgery to reduce or avoid complications caused by irregular surgery, and will ultimately benefit more patients.
    目前,我国肥胖症和2型糖尿病等代谢疾病和肥胖相关疾病的患病人数逐年增加,总患病人数及年新增患病人数均已居全球首位。大量循证医学证据表明,减重手术可有效减轻病理性肥胖症患者的多余体质量,并有效改善2型糖尿病等一系列肥胖相关代谢合并症。腹腔镜单吻合口胃旁路手术(OAGB)是最常见的减重手术术式之一,尽管 OAGB在国内开展已有超过 15年的历史,然而,针对OAGB的规范手术操作,国内仍缺少相关指南或共识。为此,中国医师协会外科医师分会肥胖和糖尿病外科医师委员会(CSMBS)发起编写首版《腹腔镜单吻合口胃旁路术规范化手术操作指南(2022版)》,旨在规范腹腔镜OAGB操作流程,为肥胖代谢外科领域的临床医生提供规范化手术操作参考,以减少或避免因手术不规范导致发生相关并发症,从而使得更多患者获益。.
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