与非足部脆性骨折相比，有关足部脆性骨折的风险因素和特征的证据有限。足部脆性骨折患者更可能是BMI较高的年轻女性。足部脆性骨折强烈预测随后的足部脆性骨折。
目的：骨质疏松症在临床上可导致脆性骨折。与非足部脆性骨折相比，足部脆性骨折的危险因素和特征的证据有限。美国骨科协会的“自己的骨骼”（OTB）是一项具有大量数据集的骨骼健康计划。这项研究的目的是检查和比较孤立的足部脆性骨折与非足部脆性骨折患者的特征。
方法：在2009年1月至2022年3月之间，发生了58,001例脆性骨折。共有750名患者患有足部脆性骨折，57,251名患者患有非足部脆性骨折，包括肩关节，手臂,弯头,前臂,手腕,脊柱,肋骨,骨盆,臀部,大腿,膝盖,胫骨/腓骨,和脚踝。人口统计,骨折史,骨骼健康因素，用药史,OTB数据库中报告了每位患者的用药情况.该数据用于我们的次要队列比较分析中，分析了足部脆性骨折和非足部脆性骨折组之间的特征和未来骨折风险。
结果：足部脆性骨折患者年轻（66.9岁）的概率明显更高，女性（91.5%），并且与非足脆性骨折患者相比具有更高的BMI(28.3kg/m2)(p<0.0001)。足部脆性骨折患者先前有足部脆性骨折的可能性增加9倍（OR=9.119，CI=7.44-11.18，p<0.001）。年轻,先前患有足部脆性骨折的女性患者未来发生足部脆性骨折的风险较高，这种风险随着BMI的增加而增加。
结论：与非足部脆性骨折患者相比，足部脆性骨折患者更可能是女性和年轻。考虑到先前的足部脆性骨折是随后的足部脆性骨折的强烈预测,足部脆性骨折是前哨事件。
方法：3（回顾性队列）。
Evidence regarding the risk factors and characteristics of those with foot fragility fractures compared to non-foot fragility fractures is limited. Foot fragility fracture patients are more likely to be younger female with a higher BMI. A foot fragility fracture is strongly predictive of a subsequent foot fragility fracture.
OBJECTIVE: Osteoporosis can clinically result in fragility fractures. Evidence regarding the risk factors and characteristics of foot fragility fractures compared to non-foot fragility fractures is limited. The American Orthopaedic Association\'s Own the Bone (OTB) is a bone health initiative with a substantial dataset. The purpose of this study was to examine and compare characteristics of patients presenting with isolated foot fragility fracture to those with a non-foot fragility fracture.
METHODS: Between January 2009 and March of 2022, 58,001 fragility fractures occurred that were included in this cohort. A total of 750 patients had foot fragility fracture(s) and 57,251 patients had a non-foot fragility fracture that included shoulder, arm, elbow, forearm, wrist, spine, ribs, pelvis, hip, thigh, knee, tibia/fibula, and ankle. Demographics, fracture history, bone health factors, medication history, and medication use for each patient were reported in the OTB database. This data was utilized in our secondary cohort comparative analysis of characteristics and the risk of future fractures between foot fragility fracture and non-foot fragility fracture groups.
RESULTS: Foot fragility fracture patients have a significantly higher probability to be younger (66.9 years old), female (91.5%), and have a higher BMI (28.3 kg/m2) compared to non-foot fragility fracture (p < 0.0001) patients. Patients with a foot fragility fracture are nine times (OR = 9.119, CI = 7.44-11.18, p < 0.001) more likely to have had a prior foot fragility fracture. Young, female patients with a prior foot fragility fracture are at higher risk of a future foot fragility fracture, and this risk increased as BMI increased.
CONCLUSIONS: Foot fragility fracture patients are more likely to be female and younger compared to patients with a non-foot fragility fracture. A foot fragility fracture is a sentinel event considering that a prior foot fragility fracture is strongly predictive of a subsequent foot fragility fracture.
METHODS: 3 (retrospective cohort).
