肠内营养配方是为无法口服营养的患者提供大量和微量营养素的产品。在这项研究中,在总共28种肠内营养配方食品中,通过电感耦合等离子体质谱法测定了已知具有潜在健康风险的23种金属的水平。根据三种不同的每日能量摄入情景计算金属暴露量(情景1=50%口服营养+50%肠内营养配方,方案2=25%口服营养+75%肠内营养配方和方案3=100%肠内营养配方),并根据非致癌健康风险进行评估。铁的平均水平,Co,Ni,Cu,Zn,Mo,Se,Li,Be,V,As,Sr,Ag,Cd,Sb,Ba,La,测定样品中的汞和铅12,000±3300、64±1.6、10±13、1300±400、8500±2500、75±30、61±21、0.34±0.36、0.05±0.08、7.3±2、1.6±0.6、457±166、0.02±0.1、0.14±0.12、0.01±0.1、74±103、0.63±0.4、0.05±0.03和0.14±0.7/μg。单独分析时,这些金属在非致癌健康风险方面被认为是安全的。然而,当所有金属的目标危险商值一起评估时,男性和女性的危害指数值均高于参考值1,表明潜在的健康风险。
Enteral nutrition formulas are products that provide macro and micronutrients to patients who cannot receive their nutrition orally. In this study, the levels of 23 metals known to have potential health risks were determined by inductively coupled plasma mass spectrometry in a total of 28 enteral nutrition formula. Metal exposure was calculated according to three different daily energy intake scenarios (Scenario 1 = 50% oral nutrition + 50% enteral nutrition formula, Scenario 2 = 25% oral nutrition + 75% enteral nutrition formula and Scenario 3 = 100% enteral nutrition formula) and evaluated in terms of non-carcinogenic health risks. The mean levels of Fe, Co, Ni, Cu, Zn, Mo, Se, Li, Be, V, As, Sr, Ag, Cd, Sb, Ba, La, Hg and Pb in the samples analyzed were determined 12,000 ± 3300, 64 ± 1.6, 10 ± 13, 1300 ± 400, 8500 ± 2500, 75 ± 30, 61 ± 21, 0.34 ± 0.36, 0.05 ± 0.08, 7.3 ± 2, 1.6 ± 0.6, 457 ± 166, 0.02 ± 0.1, 0.14 ± 0.12, 0.01 ± 0.1, 74 ± 103, 0.63 ± 0.4, 0.05 ± 0.03 and 0.14 ± 0.7 μg/L. These metals were considered safe in terms of non-carcinogenic health risks when analyzed individually. However, when the target hazard quotient values of all metals were evaluated together, hazard index values were higher than the reference value of 1, for both men and women, indicating potential health risks.