■局灶性皮质发育不良(FCD)是耐药性癫痫的重要原因,通常需要手术干预。IIb型FCD由于与抗药性癫痫发作密切相关而面临挑战。有效的管理涉及先进的成像,术中神经生理监测,和精确的手术技术.此案例研究说明了一名11岁女性的这些策略,该女性患有归因于IIb型FCD的耐药性癫痫。
■病人,一个11岁的女性,尽管有各种抗惊厥治疗,但仍有抗药性癫痫发作。术前3特斯拉(3T)MRI显示右额叶孔病灶不清。手术团队使用神经导航进行术中指导,并使用皮质脑电图进行病变切除术。病理证实IIb型FCD伴罕见同心钙化。
■FCD中的抗药性癫痫发作通常需要在药物治疗失败时进行手术。该病例强调了全面的术前评估和先进的影像学检查的重要性,比如3T核磁共振,准确识别病变。术中神经生理监测,包括脑电图,确保精确切除癫痫区。值得注意的是IIb型FCD中同心钙化的异常发现,这表明需要进一步研究以了解它们对疾病的影响。
■显微外科手术切除对于控制IIb型FCD的耐药性癫痫发作至关重要。将高级成像与术中监测相结合可提高手术精度和结果。钙化的罕见病理发现突出了FCD表现的多样性,值得进一步研究。这些技术可以显着提高耐药性癫痫患者的癫痫发作控制和生活质量。
UNASSIGNED: Focal cortical dysplasia (FCD) is a significant cause of drug-resistant epilepsy, often necessitating surgical intervention. Type IIb FCD poses challenges due to its strong association with drug-resistant seizures. Effective management involves advanced imaging, intraoperative neurophysiological monitoring, and precise surgical techniques. This
case study illustrates these strategies in an 11-year-old female with drug-resistant epilepsy attributed to Type IIb FCD.
UNASSIGNED: The patient, an 11-year-old female, had drug-resistant seizures despite various anticonvulsant treatments. Preoperative 3 Tesla (3T) MRI revealed an ill-defined lesion in the right frontal operculum. The surgical team used neuro-navigation for intraoperative guidance and electrocorticography for lesionectomy. Pathology confirmed Type IIb FCD with rare concentric calcifications.
UNASSIGNED: Drug-resistant seizures in FCD often require surgery when medications fail. This
case highlights the importance of comprehensive preoperative evaluations and advanced imaging, such as 3T MRI, to accurately identify lesions. Intraoperative neurophysiological monitoring, including electrocorticography, ensures precise resection of the epileptogenic zone. The unusual finding of concentric calcifications in Type IIb FCD is noteworthy, suggesting the need for further research to understand their impact on the disease.
UNASSIGNED: Microsurgical lesionectomy is crucial for managing drug-resistant seizures in Type IIb FCD. Combining advanced imaging with intraoperative monitoring improves surgical precision and outcomes. The rare pathological finding of calcifications highlights the diversity of FCD manifestations, warranting further study. These techniques can significantly enhance seizure control and quality of life in patients with drug-resistant epilepsy.