■口炎(UVAL)是一种主要未知的疾病,具有广泛而复杂的鉴别诊断。
■为了提供对UVAL的主要特征的描述,确定最合适的诊断过程并描述当前的治疗方法。
■我们设计了一个回顾展,使用我们机构的妇科ER数据库进行描述性队列研究。纳入标准:年龄在10至20岁之间的女性患者,怀疑在CHUV的妇科ER诊断为UVAL。数据提取:流行病学特征,临床表现,实验室测试,已建立的诊断,治疗,和溃疡的结果。
■包括15例患者进行分析;平均年龄:15岁;溃疡发作时,60%的患者为处女病;所有患者均至少有一种流感样症状伴有外阴病变;最有效的血清学检查是针对EBV,仅有一名患者出现急性疾病;出于诊断目的,进行了两次活检,两种均不确定的组织病理学分析。扑热息痛,和利多卡因凝胶;93%的病例出现消退迹象;平均随访时间为10天。Sadoghi等人的诊断算法:15例中有10例通过该算法回顾性诊断为UVAL;一半被诊断为UVAL,另一半在妇科急诊就诊时被诊断为“来历不明的溃疡”。
■我们强烈推荐Sadoghi等人开发的诊断和治疗算法。作为指导临床推理的宝贵工具,因此,改善急性外阴溃疡的管理。
UNASSIGNED: Ulcus Vulvae Acutum Lipschütz (UVAL) is a largely unknown disease with a broad and complex differential diagnosis.
UNASSIGNED: To provide a description of the main characteristics of UVAL, determine the most appropriate diagnostic process and describe the current therapeutic approach.
UNASSIGNED: We designed a retrospective, descriptive cohort study using the gynecological-ER database of our institution. Inclusion criteria: female patients aged between 10 and 20 years old with suspicion of a UVAL diagnosis at CHUV\'s gynecological ER. Data extraction: epidemiological characteristics, clinical presentation, laboratory tests, established diagnostics, treatment, and ulcer outcomes.
UNASSIGNED: 15 patients were included for the analysis; average age: 15 years old; 60% of patients were virgo at the time of ulcer onset; all patients had at least one flu-like symptom concomitant with the vulvar lesion; the most-performed serology was for EBV and acute disease was present in only one patient; for diagnostic purposes two biopsies were performed with both inconclusive histopathology analysis; the main prescribed treatments were: oral NSAIDs, Paracetamol, and Lidocaine gel; 93% of cases presented signs of regression; the average follow-up time was 10 days. The diagnostic algorithm of Sadoghi et al: 10 out of 15 cases were retrospectively diagnosed with UVAL by the algorithm; half were diagnosed with UVAL, and the other half received a diagnosis of \"ulcers of unknown origin\" at the time of the gynecological ER visit.
UNASSIGNED: We highly recommend the diagnostic and therapeutic algorithms developed by Sadoghi et al. as valuable tools to guide clinical reasoning and, consequently, improve acute vulvar ulcers management.