背景:女性性功能障碍(FSD),包括阴道松弛(VL),会导致生活质量下降,影响伴侣关系。
目的:我们旨在研究女性人群中VL和FSD的相关因素及其与其他盆底疾病的关系。
方法:这项横断面研究于2022年7月至12月在切尔西和威斯敏斯特医院进行。包括所有在泌尿妇科诊所接受临床护理的妇女。根据社会人口统计学和临床方面对参与者进行评估,盆腔器官脱垂量化系统,性功能,VL,性态度,性困扰,性生活质量,阴道症状,和盆底疾病。分析VL和FSD的未调整和调整相关因素。
结果:主要结果是确定女性人群中VL和FSD的相关因素,次要结局包括VL和盆腔器官脱垂(POP)与问卷评分的相关性.
结果:在参与者中(N=300),阴道分娩,多重奇偶校验,会阴裂伤,更年期,在报告VL的患者中,凝胶激素和凝胶激素的频率明显更高(所有P<0.05)。当与无效性相比时,基本奇偶校验和多重奇偶校验将VL的几率增加了大约4倍和12倍,分别(未调整的赔率比[OR],4.26[95%CI,2.05-8.85];或,12.77[95%CI,6.53-24.96])。更年期和会阴裂伤使VL的几率增加了4和6倍(未调整的OR,4.65[95%CI,2.73-7.93];或,6.13[95%CI,3.58-10.49])。在多变量分析中,更年期,原语奇偶校验,多重奇偶校验,和POP仍然与VL相关。
结论:奇偶校验,作为产科因素,以及更年期和持久性有机污染物的分期,作为临床因素,与VL有关。
■对VL相关因素的研究将有助于了解其病理生理学。研究设计使得不可能进行因果推断。
结论:更年期,原语奇偶校验,多重奇偶校验,在多变量分析中,POP与VL投诉高度相关。
BACKGROUND: Female sexual dysfunction (FSD), including vaginal laxity (VL), can lead to a decrease in quality of life and affect partner relationships.
OBJECTIVE: We aimed to investigate the associated factors of VL and FSD and their relationship with other pelvic floor disorders in a female population.
METHODS: This cross-sectional
study was conducted at Chelsea and Westminster Hospital from July to December 2022. All women referred to clinical care at the urogynecology clinic were included. Participants were assessed according to sociodemographic and clinical aspects, the Pelvic Organ Prolapse Quantification system, sexual function, VL, sexual attitudes, sexual distress, sexual quality of life, vaginal symptoms, and pelvic floor disorders. Unadjusted and adjusted associated factors of VL and FSD were analyzed.
RESULTS: The primary outcome was the identification of the associated factors of VL and FSD in a female population, and secondary outcomes included the association between VL and pelvic organ prolapse (POP) with the questionnaire scores.
RESULTS: Among participants (N = 300), vaginal delivery, multiparity, perineal laceration, menopause, and gel hormone were significantly more frequent in those reporting VL (all P < .05). When compared with nulliparity, primiparity and multiparity increased the odds of VL by approximately 4 and 12 times, respectively (unadjusted odds ratio [OR], 4.26 [95% CI, 2.05-8.85]; OR, 12.77 [95% CI, 6.53-24.96]). Menopause and perineal laceration increased the odds of VL by 4 and 6 times (unadjusted OR, 4.65 [95% CI, 2.73-7.93]; OR, 6.13 [95% CI, 3.58-10.49]). In multivariate analysis, menopause, primiparity, multiparity, and POP remained associated with VL.
CONCLUSIONS: Parity, as an obstetric factor, and menopause and staging of POP, as clinical factors, were associated with VL.
UNASSIGNED: The investigation of associated factors for VL will contribute to the understanding of its pathophysiology. The
study design makes it impossible to carry out causal inference.
CONCLUSIONS: Menopause, primiparity, multiparity, and POP were highly associated with VL complaints in multivariate analysis.