Etiological factors

  • 文章类型: Journal Article
    牙齿磨损由机械(磨损或磨损)和化学(侵蚀)因素引起。尽管其患病率和临床意义,准确衡量和理解其原因在日常实践中仍然具有挑战性。这项为期一年的研究对39名参与者进行了全面的检查,并在开始和12个月后进行了全面的口腔内扫描。每颗牙齿表面的体积损失超过100µ(颊,舌/腭和切牙/咬合)通过比较两个时间点的三维扫描来测量。这项研究还通过临床检查和问卷调查评估了磨损和侵蚀等因素。睡眠磨牙症参与者的牙齿磨损没有显着差异。然而,有清醒磨牙症和关节相关症状的人的前牙出现明显磨损。磨损增加与经常食用酸性饮料有关,经常游泳,口干,夜间流口水和胃灼热,而反流患者没有发现明显的磨损。所使用的方法被证明在准确评估牙齿磨损的进展方面是有效的,这很重要,因为许多患者最初可能无症状。在牙齿磨损模式中观察到的可变性强调需要开发特定的软件应用程序,以基于对患者数据库的广泛分析来立即有效地比较磨损区域。
    Dental wear arises from mechanical (attrition or abrasion) and chemical (erosion) factors. Despite its prevalence and clinical significance, accurately measuring and understanding its causes remain challenging in everyday practice. This one-year study with 39 participants involved comprehensive examinations and full-arch intraoral scans at the start and after 12 months. Volume loss exceeding 100 µ on each tooth\'s surfaces (buccal, lingual/palatine and incisal/occlusal) was measured by comparing three-dimensional scans from both time points. This study also assessed factors such as abrasion and erosion through clinical exams and questionnaires. There were no significant differences in dental wear in participants with sleep bruxism. However, noticeable wear occurred in the front teeth of those with waking bruxism and joint-related symptoms. Increased wear was associated with frequent consumption of acidic drinks, regular swimming, dry mouth, nocturnal drooling and heartburn, while no significant wear was found in patients with reflux. The used methodology proved effective in accurately assessing the progression of dental wear, which is important as many patients may initially be asymptomatic. The variability observed in dental wear patterns underscores the need to develop specific software applications that allow immediate and efficient comparison of wear areas based on extensive analysis of patient databases.
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  • 文章类型: Journal Article
    背景:口腔创伤性溃疡性病变(OTUL)在临床实践中经常遇到,然而,对其临床特征和创伤性病因的研究有限。这项回顾性研究旨在分析年龄,性别,临床特征,以及OTUL患者的创伤性病因,并为牙科临床医生优化患者护理和预防策略提供有价值的见解。
    方法:本研究共纳入1543例OTUL患者。年龄,性别,病史,收集患者的临床特点及创伤性病因分析。采用Logistic回归分析确定年龄和性别作为OTUL相关因素的意义。
    结果:该研究揭示了不同年龄段和性别之间临床特征和创伤性病因的显著差异。Logistic回归分析显示,年龄和性别均是OTUL的显著相关因素。
    结论:根据年龄和性别,OTUL的临床特征和创伤性病因似乎存在显着差异。应对所有年龄和性别群体实施更有针对性的预防战略。
    BACKGROUND: Oral traumatic ulcerative lesions (OTUL) are commonly encountered in clinical practice, yet there is limited research on their clinical characteristics and traumatic etiological factors. This retrospective study aimed to analyze the age, gender, clinical characteristics, and traumatic etiological factors in a large cohort of patients with OTUL and provide valuable insights for dental clinicians to optimize patient care and prevention strategies.
    METHODS: A total of 1543 patients with OTUL were enrolled in this study. Age, gender, medical history, clinical characteristics and traumatic etiological factors were collected and analyzed. Logistic regression analysis was performed to determine the significance of age and gender as factors related to OTUL.
    RESULTS: The study revealed significant variations in clinical characteristics and traumatic etiological factors among different age groups and between genders. Logistic regression analysis demonstrated that both age and gender were significant factors related to OTUL.
    CONCLUSIONS: The clinical characteristics of OTUL and traumatic etiological factors appear to be significantly different according to age and gender. More targeted prevention strategies should be implemented for all age and gender groups.
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  • 文章类型: Journal Article
    目的:为了确定频率,临床表现,马尾综合征(CES)的病因。
    方法:这项回顾性研究对256名参与者进行,目的分析CES疑似病例的临床表现频率和模式。纳入标准包括18岁或以上的参与者,他们有医疗记录可供审查,并有CES的红色标志症状。该研究收集了有关各种因素的信息,例如年龄,性别,在MRI上确认CES,神经功能缺损,病因因素,症状持续时间,还有更多.使用描述性统计和逻辑回归分析收集的数据,以确定MRI证明的CES和可疑CES之间的重要变量。
    结果:平均年龄为58.05±19.26岁,女性151人(58.98%),男性105人(41.02%)。大多数(50.78%)患有神经功能缺损,而其他症状包括排尿困难或尿流感觉受损(17.58%),直肠饱胀感丧失(3.12%),尿失禁或大便失禁(35.16%),双侧坐骨神经痛(21.88%),下肢神经症状(25.00%),麻醉或任何腿部无力(24.22%),以双侧坐骨神经痛为主要症状(21.88%)。症状为慢性的占47.27%,急性的占21.88%。经MRI证实的CES的机率每年增加3%。神经功能缺损与MRI证实的CES密切相关(OR=14.97),而直肠饱胀感的丧失使几率增加了10倍(OR=10.62)。
    结论:CES可以出现各种症状,包括双侧神经功能缺损,尿失禁和大便失禁,和双侧坐骨神经痛,随着年龄,严重的双侧神经功能缺损,直肠饱胀感的丧失与MRI证实的CES有关。早期诊断和治疗对于更好的结果至关重要。
    OBJECTIVE: To determine the frequency, clinical presentation, and etiological factors of cauda equina syndrome (CES).
    METHODS: This retrospective study was done on 256 participants, and aimed to analyze the frequency and patterns of clinical presentation in suspected cases of CES. The inclusion criteria included participants aged 18 or older with medical records available for review and having red-flagged symptoms for CES. The study collected information on various factors such as age, gender, confirmation of CES on MRI, neurological deficits, etiological factors, duration of symptoms, and more. The data collected was analyzed using descriptive statistics and logistic regression to identify significant variables between MRI-proven CES and suspected CES.
    RESULTS: The mean age was 58.05 ± 19.26 years, with 151 females (58.98%) and 105 males (41.02%). The majority (50.78%) had a neurological deficit, while other symptoms included difficulty initiating micturition or impaired sensation of urinary flow (17.58%), loss of sensation of rectal fullness (3.12%), urinary or faecal incontinence (35.16%), bilateral sciatica (21.88%), neurological symptoms in the lower limbs (25.00%), anaesthesia or any leg weakness (24.22%), and bilateral sciatica as the predominant symptom (21.88%). Symptoms were chronic in 47.27% and acute in 21.88%. The odds of MRI-proven CES increase by 3% per year of age. Neurological deficit was strongly associated with MRI-proven CES (OR = 14.97), while loss of sensation of rectal fullness increased the odds by 10-fold (OR = 10.62).
    CONCLUSIONS: CES can present with various symptoms, including the bilateral neurological deficit, urinary and faecal incontinence, and bilateral sciatica, with age, severe bilateral neurological deficit, and loss of sensation of rectal fullness being associated with MRI-proven CES. Early diagnosis and treatment are crucial for better outcomes.
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  • 文章类型: Journal Article
    腰椎间盘突出症(LDH)在青少年中很少见。发生在20岁或更年轻的LDH被称为青少年椎间盘突出症(JDH)。虽然成人LDH被认为是椎间盘退变的晚期,目前尚不清楚为什么青少年椎间盘破裂。本研究旨在描述JDH的MRI表现并探讨可能的病因。从2013年到2020年,对JDH患者和对照进行了识别和访谈,以评估人口统计学,一般的生活方式和家族史。MRI评估椎间盘退变,骨phy环分离,Modic改变和终板病变。检查了JDH与可疑危险因素之间的关系。共有297名JDH患者(199名男孩和98名女孩,年龄17.3±2.1岁)和185名对照(年龄17.1±2.4岁)进行了研究。年龄,BMI,暴露于日常体力劳动,定期锻炼,JDH病例和对照组的每日坐姿时间相似。与对照组相比,JDH患者有严重背痛的家族史更为常见(59.4%vs26.5%,P<0.001),以及临床确定的LDH家族史(45.0%vs12.4%,P<0.001)。在91例(36.4%)JDH患者中,102例(29.2%)突出的椎间盘中发现了骨phy环分离,而仅发生在5名(1.4%)对照参与者中(P<0.001)。总的来说,严重的椎间盘退变并不是JDH患者的突出发现.总之,骨phy环分离是JDH的常见MR特征。研究结果表明JDH的遗传介导发育模型,而不是早期椎间盘退变的模型。本文受版权保护。保留所有权利。
    Lumbar disc herniation (LDH) is rare in juveniles. LDH occurring at age 20 years or younger is referred to as juvenile disc herniation (JDH). While adult LDH is regarded as an advanced stage of disc degeneration, it remains unclear why intervertebral discs rupture in youth. This study aimed to characterize magnetic resonance imaging (MRI) findings of JDH and investigate possible etiological factors. From 2013 to 2020, JDH patients and controls were identified and interviewed to assess demographics, general lifestyles, and family histories. MRIs were evaluated for disc degeneration, epiphyseal ring separation, Modic changes and endplate lesions. The relationships between JDH and suspected risk factors were examined. A total of 297 JDH patients (199 boys and 98 girls, age 17.3 ± 2.1 years) and 185 controls (age 17.1 ± 2.4 years) were studied. Age, body mass index, exposures to daily physical labor, regular exercise, and daily sitting time were similar between JDH cases and controls. A family medical history of serious back pain was more common in JDH patients than in controls (59.4% vs. 26.5%, p < 0.001), as well as family history of clinically established LDH (45.0% vs. 12.4%, p < 0.001). Epiphyseal ring separation was identified in 102 (29.2%) herniated discs in 91 (36.4%) JDH patients, while occurring in only 5 (1.4%) control participants (p < 0.001). Overall, severe disc degeneration was not a prominent finding in JDH patients. In conclusion, epiphyseal ring separation was a common magnetic resonance feature in JDH. Findings suggest a genetically mediated developmental model of JDH, rather than a model of premature disc degeneration.
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  • 文章类型: Journal Article
    这项研究旨在调查5年后直接复合修复体的磨损行为以及相关的患者因素。
    38名患者(6名女性,32名男性;来自Radboud牙齿磨损项目的35.2±7.6y),对所有牙齿进行了直接复合修复。在进行研究之前,寻求并获得了道德批准。在治疗后1个月(基线)和5年(回忆)记录口腔内3D扫描。在六个食齿(第一磨牙和上中切牙)处测量高度损失量。患者因素(年龄,遮挡的垂直尺寸增加,咬合力,病因学评分,颌骨位置和轴承/非轴承尖端)被包括在分析中。使用带有自举功能的多级多元回归分析了这些因素对修复体磨损行为的影响。观察者可靠性通过配对t检验和Band-Altman图(p<0.05)进行检验。结果:5年后,切牙的平均高度损失为0.23±0.19mm,磨牙的平均高度损失为0.43±0.24mm(p≤0.001).患者因素对复合修复体的高度损失没有显着影响,而轴承尖点与非轴承尖点相比显示出显着更多的磨损(p≤0.001)。观察者可靠性测试证实了可重复性(相关性为0.809,DME为0.103)。
    在接受严重牙齿磨损治疗的患者中,随着时间的推移,复合修复体的磨损是一个重要且相关的因素。在这项临床研究的局限性内,发现患者因素对直接复合修复体的磨损行为没有显着影响。
    This study aimed to investigate the wear behaviour of direct composite restorations after 5 years and associated patient factors.
    38 patients (6 females, 32 males; 35.2 ± 7.6y) from the Radboud Tooth Wear Project with generalized moderate to severe tooth wear were treated with direct composite restorations on all teeth. Ethical approval was sought and granted before the study was undertaken. Intraoral 3D scans were recorded at 1 month (baseline) and 5 years (recall) after treatment. The amount of height loss was measured at six index teeth (first molars and upper central incisors). Patient factors (age, vertical dimension of occlusion increase, bite force, aetiology score, jaw position and bearing/ non-bearing cusps) were included in the analysis. Multilevel multiple regression with bootstrapping was used to analyse the influence of these factors on wear behaviour of restorations. Observer reliability was tested by paired t-tests and Band-Altman plots (p<0.05) RESULTS: After 5 years, the mean height loss was 0.23± 0.19 mm for incisors and 0.43± 0.24 mm for molars (p≤0.001). Patient factors did not show any significant influence on height loss of the composite restorations, while bearing cusps showed significant more wear compared to non-bearing cusps (p≤0.001). The observer reliability tests confirmed the repeatability (correlation of 0.809, DME 0.103).
    Wear of composite restorations is a significant and relevant factor over time in patients treated with severe tooth wear. Within the limitations of this clinical study, patient factors were found not to have a significant effect on wear behaviour of direct composite restorations.
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  • 文章类型: Journal Article
    UNASSIGNED: Bruxism is a multifactorial phenomenon that involves grinding or clenching of teeth. The parafunctional habit includes abnormal tooth wear, tooth fracture, pain, and tooth mobility, along with headaches and facial muscle hypertrophy. It is imperative for students to be conscious of teeth grinding along with its possible causes. The student will be alert to visit the dentist if required and contribute to the recognition of etiological factors, to eliminate them.
    UNASSIGNED: This study aims to find the prevalence and understanding of bruxism among Gulf Medical University (GMU) students.
    UNASSIGNED: A cross-sectional, questionnaire-based study was conducted among 451 GMU students. The parameters for data collection were age, gender, prevalence, associated signs and symptoms, causes, genetic predisposition, time of day, and effect on the appearance of teeth.
    UNASSIGNED: While 35.9% were unaware, 41.7% of our samples reported bruxism. The majority recognized temporomandibular joint and facial pain as causative, and 24.8% reported symptoms. Headache (26.4%) was prime and 7.5% were associated with fracture and abnormal tooth wear to bruxism (38.1%) experienced night bruxism. A significant number of students (32.4%) identified abnormal anterior teeth relationship as the cause and (64.3%) associated bruxism and esthetics.
    UNASSIGNED: Nearly 41.7% of the students reported bruxism. Around 35.9% of the samples were uninformed. Nearly 20.8% believed that bruxism had genetic relevance. Nearly 51.9% of the participants were asymptomatic. Around 38.1% had night bruxism and 32.4% identified abnormal anterior teeth relationship as the cause. The majority of the sample (64.3%) connected bruxism to negative effects on teeth and esthetics.
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  • 文章类型: Journal Article
    BACKGROUND: Peyronie\'s disease (PD) prevalence varies between 0.39% and 20% and studies on PD prevalence are limited.
    OBJECTIVE: This study aims to determine the prevalence of PD in males aged ≥30 years in Turkey and to evaluate etiological factors associated with it.
    METHODS: The study was conducted in 12 regions of Turkey according to the Eurostat Nomenclature of Territorial Units for Statistics 1 classification and included 1,208 patients. Survey questionnaires including questions about demographic features and basic health status as well as about diagnosis and etiology of PD were put forth to the volunteers who agreed to participate in the study. Diagnosis of probable PD was established by evaluating the questionnaires. Patients with a diagnosis of congenital penile curvature were excluded from the group with PD. Chi-square test, Fisher\'s exact test, and Mann-Whitney U test were used.
    METHODS: The primary outcome analyzed in this article was the prevalence rate of PD in Turkey and the associated comorbidities.
    RESULTS: The prevalence of PD was determined as 5.3%. The rates of participants with PD were found to be the highest in the 50-59 years group (27%) and in the North-East Region (20%). Compared with participants without PD, participants with PD were older (median: 52 interquartile range [41-64] vs 45 [37-55]; P < .001) and the rates of smokers (73% vs 60.9%; P = .036) and those having diabetes mellitus (17.5% vs 9.2%; P = .045), hypertension (14.3% vs 6.9%; P = .041), and heart failure were higher (7.9% vs 2.5%; P = .027). Male with PD symptoms preferred their partners on top during sexual intercourse (15.2% vs 34.1%; P < .001). This is the first study to evaluate premature ejaculation prevalence and related comorbidities with face-to-face interviews.
    CONCLUSIONS: The prevalence of PD was 5.3% in Turkey. Besides advanced age, smoking, position of sexual intercourse, and presence of comorbidities especially diabetes mellitus, hypertension, and heart failure were the factors associated with PD prevalence. Kadioglu A, Dincer M, Salabas E, et al. A Population-Based Study of Peyronie\'s Disease in Turkey: Prevalence and Related Comorbidities. Sex Med 2020;8:679-685.
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  • 文章类型: Journal Article
    UNASSIGNED: Periorbital hyperpigmentation (POH) is one of the common conditions seen in outpatient department. Despite of its huge prevalence, clinical data regarding its etiology and associations are still insufficient.
    UNASSIGNED: We conducted a clinico-investigational study in 50 patients of periorbital pigmentation. A detailed clinical history was recorded, clinical examination and laboratory investigation including complete blood count, vitamin B12 level, and thyroid profile are done.
    UNASSIGNED: The mean age of the patients presenting with periorbital hyperpigmentation was 29.5 years, out of 50 patients 42 (84%) were females and 8 (16%) were males. About 14% patients give positive family history of POH, history of atopy was positive in 30% of patients. History of various other habits like lack of adequate sleep, prolonged exposure to computers, rubbing eyes, and application of various cosmetics were also found to be positive in these patients. The other associated clinical findings were freckles (12%), telengectesia (2%), erythema (2%), and melasma (2%). In maximum (90%) number of patients, both upper and lower eyelids were involved and pigmentation involving >1 cm of eyelid margin was seen in 62% of patients. Laboratory investigations showed anemia in 10% of patients and low serum vitamin B12 in 12%; however, none of the patients has deranged thyroid profile.
    UNASSIGNED: POH has a multifactorial etiology and role of correcting various faulty habits is important factor in its management. Presence of anemia and low serum vitamin B12 levels also points toward need of detailed laboratory evaluation in these patients.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    OBJECTIVE: To prevent traumatic dental injuries (TDI), there is a need for vital information. This information could be reached using certain specific variables. The aim of this study, therefore, was to investigate TDI in different age groups, their etiology, and differences by gender, in Swedish children aged 0-17 years.
    METHODS: The study included 2363 children in four different age cohorts from 12 Public Dental Service clinics in Sweden. The design was a 5-year longitudinal study including yearly clinical examinations, retrospective and prospective data compiled from dental records and interviews regarding TDI.
    RESULTS: The prevalence for TDI was 37.6% (889) with no gender differences. Boys suffered more injuries during the spring and fall compared to girls. The incidence of 2.8% varied between the age groups where preschool children presented the highest incidence. No changes in prevalence for TDI were found for the years included in the study. The most common reason for TDI was Falling (42.1%). The frequencies for the etiological factors varied between the ages.
    CONCLUSIONS: The TDI prevalence showed to be stable at a high level in spite of great efforts in Sweden and worldwide to reduce it. Knowledge in why, where, and when TDI appears is therefore essential for dental personnel who will work to reduce TDI.
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