椎体曲霉病是一种罕见的传染病,病死率高。我们在此报告一名70岁的急性髓细胞性白血病患者,伴有骨髓增生异常相关的改变,非结核性分枝杆菌病,出现发烧和咳嗽的支气管扩张症.她的临床症状和实验室检查结果提示发热性中性粒细胞减少和肺炎。然而,她的临床过程因下肢无力而进一步复杂化。脊柱的磁共振成像显示,固结持续向T4和T5之间的硬膜外间隙扩散。胸腔积液的细胞学测试显示烟曲霉。我们还回顾并总结了日本以前报道的椎骨曲霉病病例。
Vertebral aspergillosis is a rare infectious disease with a high mortality rate. We herein report a 70-year-old woman with acute myelogenous leukemia with myelodysplasia-related changes, nontuberculous mycobacteriosis, and bronchiectasis who presented with a fever and cough. Her clinical symptoms and laboratory test results suggested febrile neutropenia and pneumonia. However, her clinical course was further complicated by lower extremity weakness. Magnetic resonance imaging of the spine showed consolidation contiguously spreading toward the epidural space between the T4 and T5. Cytological testing of the pleural effusion revealed Aspergillus fumigatus. We also review and summarize previously reported cases of vertebral aspergillosis in Japan.