目的:虽然囊性包虫病(CE)在不发达国家是一个严重的问题,由于最近的移民和人口流动,它也成为发达国家的严重公共卫生问题。本研究旨在探讨妊娠之间的关系,多器官参与,治疗方法,和急诊手术(未跟踪的患者),接受手术或经皮治疗的CE患者的死亡率。
方法:在本研究中,人口特征,怀孕状态,器官受累,复发和过敏反应的发展,我们调查了1997年1月至2022年1月在哈兰大学医院接受经皮或手术治疗的CE患者的重症监护需求和死亡率.
结果:在1,143例接受CE手术或经皮治疗的患者中,18怀孕了发现妊娠CE患者的死亡率明显更高(p<0.001)。发生过敏反应的患者死亡率明显较高(p<0.001)。在经皮治疗中,发现复发率(p<0.001)和过敏反应(p=0.026)显著较高.在未接受紧急手术的患者中,死亡率高三倍(p=0.108)。
结论:CE是一种可以在任何年龄发生并且可以致命的疾病。尽管多器官受累和经皮治疗可能与复发有关,它们不会直接增加死亡率。死亡率很高,尤其是在患有肺部CE的孕妇中。心脏受累,脑受累和过敏反应会增加死亡率.未进行紧急手术的患者死亡率较高。
While cystic echinococcosis (CE) is a serious problem in underdeveloped countries, it also becomes a serious public health problem in developed countries due to recent migration and population movements. This study aimed to investigate the relationship between pregnancy, multi-organ involvement, treatment methods, and emergency surgery (unfollowed patients), with mortality in patients with CE who underwent surgical or percutaneous treatment.
In this study, demographic characteristics, pregnancy status, organ involvement, development of relapse and anaphylaxis, need for intensive care and mortality rates of patients with CE treated with percutaneous or surgical methods at Harran University Hospital between January 1997 to January 2022 were investigated.
Of the 1,143 patients who underwent surgery or percutaneous treatment for CE, 18 were pregnant. Mortality was found to be significantly higher in pregnant patients with CE (p<0.001). Mortality was significantly higher in those who developed anaphylaxis (p<0.001). In percutaneous treatment, recurrence (p<0.001) and anaphylaxis (p=0.026) were found to be significantly higher. Mortality was found to be three times higher in patients without follow-up who were operated on urgently (p=0.108).
CE is a disease that can occur at any age and can be fatal. Although multi-organ involvement and percutaneous treatment may be associated with recurrence, they do not directly increase mortality. The mortality is high, especially in pregnant women with pulmonary CE. Cardiac involvement, brain involvement and anaphylaxis increase mortality. Mortality is higher in patients without follow-up who are operated on urgently.