Early mobilization

早期动员
  • 文章类型: Journal Article
    早期动员是增强术后恢复(ERAS)途径的重要组成部分之一,并已被证明可以减少并发症并优化患者预后。然而,早期动员对接受经股心导管插入术的患者的影响以及最佳动员时机的时间仍存在争议.我们旨在确定早期动员的安全性,并为接受股动脉心脏导管插入术的患者提供早期动员的最佳时机。
    我们搜索了MEDLINE,EMBASE,PubMed,WebofScience,系统评价的Cochrane数据库,CINAHL,Scopus,中国国家知识基础设施(CNKI),万方数据库,和中国科技期刊数据库(VIP)全面进行与早期动员相关的随机对照试验,探讨其对经股动脉心导管术后患者的影响。使用修订的Cochrane偏见风险工具(RoB2)和I2指数评估研究的偏倚和异质性风险。分别。采用综合Meta分析(CMA)进行Meta分析。
    我们确定了14项试验,共2653名参与者。早期活动与背痛的显着减少相关(平均差异(MD)=0.634,95%CI:0.23-1.038;p=0.002),尤其是在3h~4h与5h~6h(MD=0.737,95%CI:0.431-1.043;p=0.000)和12h与24h(OR=5.504,95%CI:1.646-18.407;p=0.006)接受早期动员指导的患者中。亚组分析的结果还显示,通过在12小时内早期动员与24小时相比,尿潴留的风险显着降低(OR=5.707,95%CI:1.859-17.521;p=0.002)类别。
    未发现早期活动会增加出血风险,血肿,假性动脉瘤,尿潴留,经股动脉心导管插入术后穿刺部位疼痛。早期动员是ERAS的一项实际举措,将动员时间提前到2h~4h可能是安全可行的。
    UNASSIGNED: Early mobilization is one of the essential components of enhanced recovery after surgery (ERAS) pathways and has been shown to reduce complications and optimize patient outcomes. However, the effect of early mobilization for patients who undergo trans-femoral cardiac catheterization and the time for optimal mobilization timing remains controversial. We aimed to identify the safety of early mobilization and provide the optimum timing for early mobilization for patients undergoing trans-femoral cardiac catheterization.
    UNASSIGNED: We searched MEDLINE, EMBASE, PubMed, Web of Science, Cochrane databases of systematic reviews, CINAHL, SCOPUS, China National Knowledge Infrastructure (CNKI), Wan Fang Database, and Chinese Science and Technology Periodical Database (VIP) comprehensively for randomized controlled trials associated with early mobilization, to explore its effects on patients after a trans-femoral cardiac catheterization. The risk of bias and heterogeneity of studies was assessed using the Revised Cochrane risk-of-bias tool for randomized trials (RoB 2) and I 2 index, respectively. The comprehensive Meta-analysis (CMA) was adopted to perform the meta-analysis.
    UNASSIGNED: We identified 14 trials with 2653 participants. Early mobilization was associated with significant decrease in back pain (mean difference (MD) = 0.634, 95% CI: 0.23-1.038; p = 0.002), especially in patients receiving instruction for early mobilization in 3 h~4 h versus 5 h~6 h (MD = 0.737, 95% CI: 0.431-1.043; p = 0.000) and 12 h versus 24 h (OR = 5.504, 95% CI: 1.646-18.407; p = 0.006) categories. The results of subgroup analysis also showed a significant risk reduction in urinary retention by early mobilization in 12 h versus 24 h (OR = 5.707, 95% CI: 1.859-17.521; p = 0.002) category.
    UNASSIGNED: Early mobilization has not been shown to increase the risk of bleeding, hematoma, pseudoaneurysm, urinary retention, and pain at the puncture site after trans-femoral cardiac catheterization. Early mobilization is a practical initiative in ERAS, and it may be safe and feasible to advance the mobilization to 2 h~4 h.
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  • 文章类型: Journal Article
    由于解剖位置和潜在的并发症风险,股骨导管是烧伤ICU移动性进展的已知障碍。这项研究的目的是检查实施股骨导管动员指南后的结局和并发症发生率。以及确定在烧伤人群中使用股骨导管动员的安全性和可行性。在实施新的股骨导管移动指南之前和之后,对17例患者进行了回顾性审查。共34例。在至少一根股骨导管到位的情况下,对烧伤治疗记录进行了审查。包括动脉,中央,和透析导管.人口统计数据,入学统计,线放置时间线,记录了非动员组(NMG)和动员组(MG)在治疗期间实现的活动能力。所审查的34例患者共放置了99条线路(30NMG,69毫克)。MG移动协议的变化导致更多的治疗期(n=516vs281)和活动移动期的显着增加(n=83vs5,p<0.001),包括146个总的移动活动,如过渡到椅子,倾斜台,床边(EOB),站立,活跃的椅子转移,步行,和周期测功。主动活动期间未发生导管相关不良事件,且无与参与活动相关的并发症。这项研究支持单独的股骨导管的存在不应限制移动性干预的进展。利用临床判断和专业培训,烧伤治疗师可以安全地动员ICU患者的股骨导管到位。
    Femoral catheters are commonly viewed as a barrier to Burn ICU mobility progression due to anatomical location and potential risk of complications. The purpose of this review was to examine outcomes and complication rates following implementation of femoral catheter mobilization guidelines, as well as determine safety and feasibility of mobilization with femoral catheters in place within the burn population. A retrospective review was completed on 17 patients prior to and following the implementation of new femoral catheter mobility guidelines, 34 patients total. Burn therapy notes were reviewed for burn admissions with at least 1 femoral catheter in place, including arterial, central, and dialysis catheters. Demographic data, admission statistics, line placement timelines, and active mobility achieved during therapy sessions were recorded for both the nonmobilization group (NMG) and mobilization group (MG). The 34 patients reviewed had 99 total lines placed (30 NMG, 69 MG). Change in mobility protocols for the MG resulted in more therapy sessions (n = 516 vs 281) and a significant increase in active mobility sessions (n = 83 vs 5, P < .001), including 146 total mobility activities such as transitions to chairs, tilt table, sitting edge of bed, standing, active chair transfers, ambulation, and cycle ergometry. No catheter-associated adverse events occurred during active mobility sessions and no complications were associated with participation in mobility. This review supports that the presence of femoral catheters alone should not limit the progression of mobility interventions with the use of clinical judgment in specialty-trained burn therapists.
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  • 文章类型: Journal Article
    肱骨近端骨折(PHFs)是老年人常见的骨折,通常采用保守固定治疗。然而,对于选择早期还是晚期常规动员尚无共识,考虑到他们的结果。本文从肢体功能方面回顾了一周和三周固定期临床结局的比较研究,疼痛强度,以及采用PHF非手术治疗后的并发症。
    当前的系统审查始于搜索PubMed,Scopus,和WebofScience数据库用于PHF患者的随机临床试验(RCT),以比较接受一周动员(早期动员)和接受三周动员(晚期动员)的患者之间的临床结果。我们还进行了一项荟萃分析,以比较两组在随访3个月和6个月时的肢体功能和疼痛水平。
    七个RCT中有五个有足够的数据可纳入荟萃分析。定量结果表明,早期动员患者在三个[加权平均差异(WMD):5.15(CI95%:0.68-9.62)]和六个[WMD:3.51(CI95%:0.43-6.60)]个月时肢体功能改善,但不是在12个月的随访。在任何一个三点,六,或者12个月,两组的疼痛强度无差异。
    这项审查支持在一周内采用早期动员来进行PHF的非手术管理。然而,为了比较长期效果,需要更多的临床试验和更长时间的随访.
    UNASSIGNED: Proximal humerus fractures (PHFs) are common fractures in the elderly and are typically treated conservatively with immobilization. However, there is no consensus on whether to choose early or late conventional mobilization, taking their outcomes into account. This paper reviews comparative studies on the clinical outcomes of one- and three-week immobilization periods in terms of limb function, pain intensity, and complications following the adoption of the non-surgical treatment of PHF.
    UNASSIGNED: The current systematic review started with searching PubMed, Scopus, and Web of Science databases for randomized clinical trials (RCTs) on PHF patients to compare the clinical outcomes between patients receiving the one-week mobilization (early mobilization) and those receiving the three-week mobilization (late mobilization). We also performed a meta-analysis to compare the two groups\' limb function and pain levels at three and six months of follow-up.
    UNASSIGNED: Five of the seven RCTs had adequate data to be included in the meta-analysis. The quantitative results showed that the early mobilized patients had improved limb function at three [weighted mean difference (WMD): 5.15 (CI 95%: 0.68-9.62)] and six [WMD: 3.51 (CI 95%: 0.43-6.60)] months, but not at 12 months of follow-up. At either three, six, or 12 months, there was no difference in pain intensity between the two groups.
    UNASSIGNED: This review supports the adoption of early mobilization at one week for the non-operative management of PHFs. However, to compare the long-term effects, more clinical trials with longer follow-ups are needed.
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  • 文章类型: Journal Article
    具体的外科手术,例如上腹部和胸外科手术,与术后肺部并发症(PPC)的易感性增加有关。在上腹部手术中,PPC的发生率可能在20-90%之间变化。可以通过使用增加肺活量和鼓励灵感的治疗程序来最小化。这篇综述旨在研究促进肺扩张的现有循证干预措施的有效性。从而防止PPC。
    我们主要集中于术前教育对激励肺活量计的现有证据,早期动员,定向咳嗽,深呼吸练习,胸部理疗,和吸气肌训练(IMT)以防止PPC。文献检索仅限于实验,观察性研究,系统审查,以及过去15年发表的文章,2007年1月-12月2022年,在PubMed和GoogleScholar中。
    此初始搜索共产生5301篇文章。所有标题与主题无关的文章都被删除。1050条记录被筛选,最后审查了22篇文章,包括13项随机对照试验(RCT),四个系统审查,一次回顾性审查,三项观察性研究,和一项非实验性研究。我们的审查揭示了个人干预的混合证据,包括但不限于激励肺活量测定,吸气肌训练,早期动员,咳嗽,深呼吸,等。一些研究认为干预是有效的;另一些研究则暗示干预的选择没有实质性差异。
    文献综述得出的结论是,接受多种干预的患者术后肺功能明显改善。然而,需要进行明确的研究来巩固这一结论。
    UNASSIGNED: Specific surgical procedures, such as upper abdominal and thoracic surgery, are connected to an increased predisposition of postoperative pulmonary complications (PPCs). The incidence of PPCs could vary approximately between 20-90% with upper abdominal surgery, which can be minimized by using treatment procedures that increase lung capacity and encourage inspiration. This review aims to examine the effectiveness of already existing evidence-based interventions that promote lung expansion, thereby preventing PPCs.
    UNASSIGNED: We mainly focused on the existing evidence of preoperative education on the incentive spirometer, early mobilization, directed coughing, deep breathing exercises, chest physiotherapy, and inspiratory muscle training (IMT) to prevent PPCs. The literature search was limited to experimental, observational studies, systemic reviews, and articles published in the last 15 years, January 2007- Dec. 2022, in PubMed and Google Scholar.
    UNASSIGNED: This initial search yielded a total of 5301 articles. All articles with titles not related to the topic were eliminated. 1050 records were screened, and the final review was conducted with 22 articles, including 13 randomized controlled trials (RCTs), four systemic reviews, one retrospective review, three observational studies, and one non-experimental study. Our review reveals mixed evidence for individual interventions, including but not limited to incentive spirometry, inspiratory muscle training, early mobilization, cough, deep breathing, etc. Some studies maintain that intervention is effective; others imply there is no substantial difference in the choice of intervention.
    UNASSIGNED: The literature review concluded that patients who received multiple interventions showed significant improvement in pulmonary function postoperatively. However, definitive studies need to be conducted to solidify this conclusion.
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  • 文章类型: Journal Article
    目的:本范围综述的目的是调查在重症监护病房接受机械通气患者的随机临床试验(RCTs)中的动员剂量报告。
    方法:在本范围审查中,在相关电子数据库中搜索了从成立到2022年12月发布的RCT。分析了成人接受机械通气(>48小时)和任何早期动员方式的试验。两名独立作者筛选,选定,并提取数据。干预组(IG)和比较组(CG)的动员剂量被评估为来自运动报告模板共识(CERT)主要项目的报告项目/总数的比例。
    结果:包括23个RCT,包括2707名患者(来自IG的1358名和来自CG的1349名),涉及神经肌肉电刺激的研究(n=7),渐进流动性(n=6),腿部骑行(n=3),倾斜台(n=1),和多组分(n=6)动员。CERT项目的汇总报告为68%(IG为86%,CG为50%)。报告最多的CERT项目是IG的运动类型(100%)和每周频率(100%),而报告最少的是CG的强度(4%)和个体化(22%)。不管是哪个群体,个性化,programming,和动员强度是报告最少的项目。八个IG(35%)报告了所有CERT项目,而没有CGs报告所有这些。
    结论:确定了重症监护病房随机对照试验的动员剂量报告缺陷,特别是对于接受机械通气的成年人的运动强度。三分之一的IG报告了所有运动剂量项目,而没有CG报告所有这些。未来的研究应该调查最佳剂量报告的细节,尤其是CG。
    结论:缺乏剂量报告可能部分解释了早期动员试验荟萃分析结果的不一致,因此限制了重症监护病房临床实践的解释。
    OBJECTIVE: The aim of this scoping review was to investigate the mobilization dose reporting in the randomized clinical trials (RCTs) of patients receiving mechanical ventilation in the intensive care unit.
    METHODS: In this scoping review, RCTs published from inception to December 2022 were searched in relevant electronic databases. Trials that involved adults receiving mechanical ventilation (>48 hours) and any early mobilization modality were analyzed. Two independent authors screened, selected, and extracted data. The mobilization doses of the intervention groups (IGs) and the comparator groups (CGs) were assessed as the proportion of reported items/total applicable from the main items of the Consensus on Exercise Reporting Template (CERT).
    RESULTS: Twenty-three RCTs comprising 2707 patients (1358 from IG and 1349 from CG) were included, involving studies on neuromuscular electrical stimulation (n = 7), progressive mobility (n = 6), leg cycling (n = 3), tilt table (n = 1), and multicomponent (n = 6) mobilization. The pooled reporting of CERT items was 68% (86% for IG and 50% for CG). The most reported CERT items were type of exercise (100%) and weekly frequency (100%) for IG, whereas the least reported were intensity (4%) and individualization (22%) for CG. Regardless of the group, individualization, progression, and intensity of mobilization were the least reported items. Eight IGs (35%) reported all CERT items, whereas no CGs reported all of them.
    CONCLUSIONS: Deficits in mobilization dose reporting of intensive care unit RCTs were identified, especially for exercise intensity in adults receiving mechanical ventilation. One-third of IG reported all exercise dosing items, whereas no CG reported all of them. Future studies should investigate the details of optimal dosage reporting, particularly for CG.
    CONCLUSIONS: The lack of dose reporting may partially explain the inconsistency in the meta-analysis results of early mobilization trials, thus limiting the interpretation for clinical practice in the intensive care unit.
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  • 文章类型: Journal Article
    肥胖在重症监护室越来越普遍,对医疗保健系统和专业人员提出了重大挑战,包括康复团队。照顾患有肥胖症的危重患者涉及解决复杂的问题。尽管在危重病期间早期动员的做法已经确立和安全,在康复方面,肥胖患者人群中不同的临床障碍和情况需要全面了解.这包括认识到代谢支持的重要性,无创和有创通气支持,和他们的断奶过程是必不可少的先决条件。物理治疗师,与多学科团队合作,在确保重症监护环境中的适当评估和功能康复方面发挥关键作用。这篇综述旨在为重症监护病房肥胖患者的关键管理和康复原则提供重要见解。
    Obesity has become increasingly prevalent in the intensive care unit, presenting a significant challenge for healthcare systems and professionals, including rehabilitation teams. Caring for critically ill patients with obesity involves addressing complex issues. Despite the well-established and safe practice of early mobilization during critical illness, in rehabilitation matters, the diverse clinical disturbances and scenarios within the obese patient population necessitate a comprehensive understanding. This includes recognizing the importance of metabolic support, both non-invasive and invasive ventilatory support, and their weaning processes as essential prerequisites. Physiotherapists, working collaboratively with a multidisciplinary team, play a crucial role in ensuring proper assessment and functional rehabilitation in the critical care setting. This review aims to provide critical insights into the key management and rehabilitation principles for obese patients in the intensive care unit.
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  • 文章类型: Journal Article
    目的:综合重症监护患者对早期动员的看法的定性研究结果,以确定他们的需求并了解影响他们参与的因素。
    方法:对患者在重症监护病房早期活动体验的研究进行了检索。通过搜索五个英文和四个中文电子数据库进行了全面搜索。系统审查是按照乔安娜·布里格斯研究所对定性证据进行系统审查的方法进行的,并采用专题综合法进行数据分析。
    结果:共纳入8项研究。形成了八个描述性主题:患者的自决需求,患者关系需要,患者对能力和自我控制的需求,身体功能的感知益处,增强自信心,负面情绪,不愉快的经历和痛苦,消极态度,并确定了与患者对重症监护病房早期动员的看法相关的三个分析主题,包括患者在早期动员期间的需求,促进者促使患者在早期动员中采取行动,和影响患者早期动员行动的障碍。
    结论:许多因素影响重症患者早期活动的行动。更好地了解患者的潜在需求和对重症监护病房早期动员的心理反应可能有助于卫生专业人员制定策略以提高早期动员的质量。
    结论:认识和制定满足需求的策略对于改善患者在重症监护病房的早期动员行动至关重要。.因此,了解早期动员中需求支持与患者行动之间的关系可以帮助他们在动员期间提供更好的支持服务。
    OBJECTIVE: To synthesize qualitative research findings on intensive care patients\' perceptions of early mobilization to identify their needs and understand the factors influencing their participation.
    METHODS: Studies that explored patients\' experiences of early mobilization within the intensive care unit were searched. A comprehensive search was conducted by searching five English and four Chinese electronic databases. The systematic review was carried out in line with the Joanna Briggs Institute methodology for systematic reviews of qualitative evidence, and also the thematic synthesis method was used to analyze the data.
    RESULTS: A total of eight studies were included. Eight descriptive themes were formed: patients\' self-determination needs, patients\' relationship needs, patients\' needs for competency and self-control, perceived benefits of physical function, increased self-confidence, negative emotions, unpleasant experiences and suffering, negative attitudes, and three analytical themes related to patients\' perceptions of early mobilization in the intensive care unit were identified, including patients\' needs during early mobilization, facilitators prompting patients\' actions in early mobilization, and obstacles influencing patients\' actions in early mobilization.
    CONCLUSIONS: Many factors influence the critically ill patients\' actions in early mobilization. A better understanding of patients\' potential needs and psychological responses to early mobilization in the intensive care unit may help health professionals develop strategies to promote the quality of early mobilization.
    CONCLUSIONS: Recognizing and developing the strategies to meet the needs are essential to improve the patients\' actions in early mobilization in the intensive care unit.. Therefore, understanding the relationship between needs support and patients\' actions in early mobilization can help them provider better support services during mobilization.
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  • 文章类型: Meta-Analysis
    在某些情况下,住院患者的早期动员是有益的。这已在急性心力衰竭(HF)患者的临床实践中应用。然而,其当前的定义,有效性,和安全没有得到很好的建立。这篇综述旨在阐明当前“早期动员”的定义,并总结其在急性HF中的有效性和安全性。我们进行了范围审查以定义早期动员(第1部分),并进行了系统审查和荟萃分析(第2部分)以评估其有效性和安全性。对于第1部分,我们搜索了MEDLINE(Ovid),在第二部分,我们搜索了Cochrane中央控制试验登记册,MEDLINE(Ovid),Embase(ProQuest对话框),CINAHL,还有PEDro.我们在第1部分中纳入了12项研究,并将早期动员定义为基于协议的干预措施或入院后3天内的步行。根据这个定义,第2部分包括两项观察性研究,无随机对照试验.与对照组相比,早期动员可能会导致再入院率大大降低(两项研究,283名参与者:比值比0.25,95%置信区间0.14至0.42;I2=0%;低确定性证据)。我们无法定义频率,强度,或数量,因为许多纳入的研究没有描述它们。在结论中,我们的审查表明,早期动员,定义为基于协议的干预或入院后3天内步行,可能与急性HF患者的低再入院率有关。未来的研究是必不可少的,调查早期动员和可能的结果之间的因果关系。
    Early mobilization of hospitalized patients is beneficial under certain circumstances. This has been applied in clinical practice for patients with acute heart failure (HF). However, its current definition, effectiveness, and safety are not well established. This review aimed to clarify the current definition of \"early mobilization,\" and summarize its effectiveness and safety in acute HF. We conducted a scoping review to define early mobilization (Part 1) and a systematic review and meta-analysis (Part 2) to evaluate its effectiveness and safety. For Part 1, we searched MEDLINE (Ovid), and for Part 2, we searched the Cochrane Central Register of Controlled Trials, MEDLINE (Ovid), Embase (ProQuest Dialog), CINAHL, and PEDro. We included 12 studies in Part 1 and defined early mobilization as protocol-based interventions or walking within 3 days of admission. Based on this definition, two observational studies were included in Part 2, with no randomized controlled trials. Early mobilization may result in a large reduction in the readmission rate compared with that of the control (two studies, 283 participants: odds ratio 0.25, 95 % confidence interval 0.14 to 0.42; I2 = 0 %; low certainty evidence). We could not define frequency, intensity, or quantity because many of the included studies did not describe them. In conclusions, our review suggests that early mobilization, defined as protocol-based interventions or walking within 3 days of admission, may be associated with a low readmission rate in patients with acute HF. Future studies are essential, to investigate the causal relationship between early mobilization and possible outcomes.
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  • 文章类型: Journal Article
    本范围审查的目的是总结有关影响住院患者心脏康复(ICR)的提供和接受的障碍和促进因素的文献。
    使用PsycINFO进行了文献检索,MEDLINE,EMBASE,CINAHL和AgeLine。如果研究在2000年以后以英语发表,并且集中于正在接受某种形式的ICR的成年人(例如,运动咨询和培训,心脏健康生活教育)。对于符合纳入标准的研究,关于作者的描述性数据,Year,研究设计,提取干预类型。
    通过文献检索,共发表了44,331篇出版物,其中229项研究符合纳入标准。ICR计划差异很大,通常侧重于促进体育锻炼和患者教育。障碍和促进者通过患者进行分类,提供商和系统级因素。个人特征以及提供者的知识和功效被归类为ICR交付和吸收的障碍和促进者。团队运作,缺乏资源,方案协调,评估中的不一致是ICR交付和吸收的主要障碍。影响ICR实施和参与的主要促进者包括认证和专业协会以及以患者和家庭为中心的实践。
    ICR计划可以非常有效地改善心血管疾病患者的健康状况。我们的审查确定了几个病人,提供者,以及作为ICR交付和吸收的障碍和促进者的系统级考虑。未来的研究应该探索如何鼓励ICR工作人员和患者的健康促进知识。
    UNASSIGNED: The purpose of this scoping review was to summarize the literature on barriers and facilitators that influence the provision and uptake of inpatient cardiac rehabilitation (ICR).
    UNASSIGNED: A literature search was conducted using PsycINFO, MEDLINE, EMBASE, CINAHL and AgeLine. Studies were included if they were published in English after the year 2000 and focused on adults who were receiving some form of ICR (eg, exercise counselling and training, education for heart-healthy living). For studies meeting inclusion criteria, descriptive data on authors, year, study design, and intervention type were extracted.
    UNASSIGNED: The literature search resulted in a total of 44,331 publications, of which 229 studies met inclusion criteria. ICR programs vary drastically and often focus on promoting physical exercises and patient education. Barriers and facilitators were categorized through patient, provider and system level factors. Individual characteristics and provider knowledge and efficacy were categorized as both barriers and facilitators to ICR delivery and uptake. Team functioning, lack of resources, program coordination, and inconsistencies in evaluation acted as key barriers to ICR delivery and uptake. Key facilitators that influence ICR implementation and engagement include accreditation and professional associations and patient and family-centred practices.
    UNASSIGNED: ICR programs can be highly effective at improving health outcomes for those living with CVDs. Our review identified several patient, provider, and system-level considerations that act as barriers and facilitators to ICR delivery and uptake. Future research should explore how to encourage health promotion knowledge amongst ICR staff and patients.
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  • 文章类型: Journal Article
    早期动员(EM)对重症监护病房(ICU)患者的影响尚不清楚。对随机对照试验进行荟萃分析,以评估其在机械通气的成年ICU患者中的效果。
    我们搜索了发表在Medline,Embase,和CENTRAL数据库(从成立到2022年11月)。根据时间和类型的不同,干预组定义为系统EM组,比较组分为晚期动员组和标准EM组。主要结果是死亡率。次要结果是ICU住院时间,机械通气(MV)的持续时间,和不良事件。EM对干预组和对照组的180天死亡率和住院死亡率没有影响(RR1.09,95%CI0.89-1.33,p=0.39)。系统性EM减少了ICU住院时间(LOS)(MD-2.18,95%CI-4.22--0.13,p=0.04)和MV持续时间(MD-2.27,95%CI-3.99--0.56,p=0.009),但与标准EM组相比,它可能会增加患者不良事件的发生率(RR1.99,95%CI1.25-3.16,p=0.004).
    系统性EM对机械通气的成年ICU患者的短期或长期死亡率没有显着影响,但系统性EM可以降低ICULOS和MV持续时间。
    UNASSIGNED: The effects of early mobilization (EM) on intensive care unit (ICU) patients remain unclear. A meta-analysis of randomized controlled trials was performed to evaluate its effect in mechanically ventilated adult ICU patients.
    UNASSIGNED: We searched randomized controlled trials (RCTs) published in Medline, Embase, and CENTRAL databases (from inception to November 2022). According to the difference in timing and type, the intervention group was defined as a systematic EM group, and comparator groups were divided into the late mobilization group and the standard EM group. The primary outcome was mortality. The secondary outcomes were ICU length of stay, duration of mechanical ventilation (MV), and adverse events. EM had no impact on 180-day mortality and hospital mortality between intervention groups and comparator groups (RR 1.09, 95% CI 0.89-1.33, p = 0.39). Systemic EM reduced the ICU length of stay (LOS) (MD -2.18, 95% CI -4.22--0.13, p = 0.04) and the duration of MV (MD -2.27, 95% CI -3.99--0.56, p = 0.009), but it may increase the incidence of adverse events in patients compared with the standard EM group (RR 1.99, 95% CI 1.25-3.16, p = 0.004).
    UNASSIGNED: Systematic EM has no significant effect on short- or long-term mortality in mechanically ventilated adult ICU patients, but systematic EM could reduce the ICU LOS and duration of MV.
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