背景:公认的是,精神分裂症患者的情绪感知缺陷会影响长期的社会和职业功能。了解影响这些损害的因素对于有针对性的干预措施以改善恢复非常重要。在一般人群中,与男性相比,女性倾向于表现出更大的情感感知。这种性别差异在精神分裂症中是否持续存在尚不清楚。与男性相比,被诊断为精神分裂症的女性倾向于有更高的发病年龄和更好的病前功能,但不一定有更好的结果。社会认知障碍的有效治疗与长期功能康复高度相关。对精神分裂症患者中女性和男性情绪感知的认知缺陷的更多了解可能有助于更好地针对个人进行干预。
目的:本系统综述旨在整理,合成,并批判性地评估考虑生物性别(女性和男性)对精神分裂症患者情绪感知的影响的证据。
方法:这是基于PRISMA-P(系统评价和荟萃分析方案的首选报告项目)指南的系统评价方案。MEDLINE电子数据库,Embase,中部,CINAHL,和PsycINFO将被系统地搜索。要包括在本审查中,研究必须比较18岁以上的男性和女性参与者的情绪认知,这些参与者主要诊断为精神分裂症谱系障碍。定性研究,病例报告,案例系列,未发表的手稿,没有用英语报道的研究将被排除在外。关键搜索策略将包括以下术语的组合:“男人,\"\"男性,\"\"男人,\"\"女,\"\"女人,\"\"女人,\"\"性别,\"\"性别,“\”情绪感知,\"\"情绪处理,\"\"精神分裂症,\"\"精神分裂症,“\”精神病,\“\”精神病,\"\"精神病,\"\"精神病患者,\“\”分裂情感,\“\”分裂型人格障碍,\"和\"分裂。“确定的研究将上传到基于网络的Covidence系统审查管理软件。将使用相关的JoannaBriggs研究所清单工具评估个别研究的偏倚风险。等级(建议评估等级,发展,和评估)系统也将用于评估证据基础的强度。将对研究结果进行综合,以对现有文献进行系统总结。如果有足够的可比数据可以进行荟萃分析,将进行随机效应荟萃分析.
结果:该系统评价于2023年10月在PROSPERO(国际前瞻性系统评价登记册)注册。研究标题和摘要的搜索和筛选目前正在进行中。预计数据将在2024年7月进行提取和分析。
结论:结果将有助于提高对男性和女性精神分裂症患者的社会认知状况的理解。这些知识有望为干预措施的适应提供信息,以改善功能结果。
背景:PROSPEROCRD42023463561;https://tinyurl.com/34sr3rnf.
■DERR1-10.2196/56977。
BACKGROUND: It is well established that individuals with schizophrenia experience deficits in emotional perception that can impact long-term social and occupational functioning. Understanding the factors that impact these impairments is important for targeting interventions to improve recovery. In the general population, compared with males, females tend to show greater perception of
emotions. Whether this sex difference persists in schizophrenia is less clear. In contrast to males, females diagnosed with schizophrenia tend to have a higher age of disease onset and better premorbid functioning but do not necessarily have better outcomes. Effective treatments for social cognitive impairments are highly relevant to long-term functional rehabilitation. A greater understanding of the cognitive deficits in emotional perception within females and males living with schizophrenia may assist interventions to be better tailored to individuals.
OBJECTIVE: This systematic
review aims to collate, synthesize, and critically appraise evidence considering the influence of biological sex (female and male) on the emotional perception of individuals with schizophrenia.
METHODS: This is a systematic
review protocol based on the PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols) guidelines. The electronic databases MEDLINE, Embase, CENTRAL, CINAHL, and PsycINFO will be systematically searched. To be included in this
review, studies must compare the emotional perceptions of male and female participants older than 18 years who have a primary diagnosis of a schizophrenia spectrum disorder. Qualitative studies, case reports, case series, unpublished manuscripts, and studies not reported in English will be excluded. Key search strategies will include combinations of the following terms: \"men,\" \"male,\" \"man,\" \"female,\" \"women,\" \"woman,\" \"sex,\" \"gender,\" \"emotional perception,\" \"emotional processing,\" \"schizophrenia,\" \"schizophren,\" \"psychotic disorders,\" \"psychosis,\" \"psychoses,\" \"psychotic,\" \"schizoaffective,\" \"schizotypal personality disorder,\" and \"schizotyp.\" Identified studies will be uploaded to the web-based Covidence systematic review management software. The risk of bias for individual studies will be assessed using the relevant Joanna Briggs Institute checklist tools. The GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system will also be used to evaluate the strength of the evidence base. Findings will be synthesized to provide a systematic summary of the existing literature. If sufficiently comparable data to permit meta-analysis emerges, a random-effects meta-analysis will be performed.
RESULTS: This systematic
review was registered with the PROSPERO (International Prospective Register of Systematic Reviews) in October 2023. The search and screening of study titles and abstracts are currently underway. Data are expected to be extracted and analyzed in July 2024.
CONCLUSIONS: Results will contribute to an improved understanding of the social cognitive profiles of males and females with schizophrenia. This knowledge is expected to inform the adaptation of interventions to improve functional outcomes.
BACKGROUND: PROSPERO CRD42023463561; https://tinyurl.com/34sr3rnf.
UNASSIGNED: DERR1-10.2196/56977.