Dual energy computed tomography

双能量计算机断层扫描
  • 文章类型: Case Reports
    背景:双能量计算机断层扫描(DECT)是一种允许查看计算机断层扫描光谱图像的技术。这种方法,由于能够呈现特定的元素和物质(如水,钙和碘),可用于定位选定类型的组织。甲状腺组织由于富含内源性碘,即使不施用造影剂也可以定位。
    方法:在介绍的病例中,作者使用甲状腺衍生组织中内源性碘积累的特征来诊断分化型甲状腺癌转移。在患者1中,DECT是符合手术资格的决定性参数。由于在患者2中使用DECT,因此可以直接定位甲状腺癌转移,使用标准技术(闪烁显像和[18F]FDGPET/CT)是不可行的。它有助于进行靶向活检并确认甲状腺癌转移的诊断,允许引入索拉非尼贝治疗。
    结论:DECT证实了它在甲状腺组织定位中的效用,包括分化型甲状腺癌(DTC)转移。该方法可以在未来使用,特别是在超声检查中没有DTC定位的边缘或模棱两可的病例中,RAI闪烁显像,或[18F]FDGPET/CT,以及有造影CT禁忌症的患者。
    BACKGROUND: Dual Energy Computed Tomography (DECT) is a technology that allows for viewing computed tomography spectral images. This method, due to ability of presenting specific elements and substances (like water, calcium and iodine), can be used to locate selected type of tissues. Thyroid tissue due to being rich in endogenous iodine, can be located even without administration of contrast agent.
    METHODS: In presented cases authors used a feature of accumulating endogenous iodine in thyroid derivative tissue for diagnosis of differentiated thyroid cancer metastases. In Patient One DECT was a decisive parameter qualifying for the surgery. Due to use of DECT in Patient Two it was possible to directly localize thyroid cancer metastases, which was unfeasible using standard techniques (scintigraphy and [18 F]FDG PET/CT). It helped to perform targeted biopsy and confirm diagnosis of thyroid cancer metastases, allowing to introduce treatment with sorafenibe.
    CONCLUSIONS: DECT confirmed its utility in locating thyroid tissues, including differentiated thyroid cancer (DTC) metastases. The method could be used in the future, especially in borderline or ambiguous cases with no localization of DTC in ultrasonography, RAI scintigraphy, or [18 F]FDG PET/CT, and among patients having contraindications for contrast-CT.
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  • 文章类型: Case Reports
    痛风是炎性关节炎,并且通过其急性痛风发作的典型临床表现或通过慢性痛风石沉积的存在而容易被医疗保健提供者识别。然而,在某些情况下,慢性痛风性关节病的诊断更具挑战性,特别是在没有以前的痛风病史和其他特征性检查结果的情况下。我们介绍了一例慢性痛风性关节病,其特征是模仿类风湿性关节炎,涉及手脚的多个小关节和其他大关节。他的血清尿酸较高,并获得了脚和脚踝的双能CT(DECT)扫描,显示多关节痛风。鉴于关节糜烂,他开始服用卵石酶,和活动的严重限制,导致尿酸单钠晶体的降低和症状的改善。
    Gout is inflammatory arthritis and is easily recognizable by healthcare providers by its typical clinical presentation of acute gout flare or by the presence of chronic tophaceous deposits. However, chronic gouty arthropathy can be more challenging to diagnose in some cases, especially in the absence of a previous history of gout and other characteristic findings on exam. We present a case of chronic gouty arthropathy with features mimicking rheumatoid arthritis involving multiple small joints of hands and feet and other large joints. He had high serum uric acids and a dual-energy CT (DECT) scan of the feet and ankles was obtained which showed polyarticular gout. He was started on pegloticase in view of joint erosions, and severe limitations in activity which resulted in a lowering of monosodium urate crystals and symptomatic improvement.
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  • 文章类型: Case Reports
    严重的脊柱疼痛是痛风的不寻常表现。由于其稀有性和难以获得用于晶体分析的关节液或组织,双能量计算机断层扫描(DECT)可能是治疗轴向痛风的有用成像方式。
    两名患者独立送往一家主要教学医院,随后显示严重的脊柱疼痛是由于痛风。第一位患者出现背痛和发烧,最初被认为患有腰椎小关节化脓性关节炎。第二例出现严重的背痛。在这两种情况下,DECT提示脊髓组织中尿酸单钠沉积是其表现的原因。
    轴性痛风在严重脊柱疼痛的鉴别诊断中应考虑。DECT研究可能是治疗脊髓痛风的有用诊断工具。
    UNASSIGNED: Severe spinal pain is an unusual presentation of gout. Due to its rarity and the difficulty of obtaining joint fluid or tissue for crystal analysis, dual energy computed tomography (DECT) may be a useful imaging modality in the management of axial gout.
    UNASSIGNED: Two patients independently presented to a major teaching hospital with severe spinal pain subsequently shown to be due to gout. The first patient presented with back pain and fevers and was initially thought to have lumbar facet joint septic arthritis. The second case presented with severe back pain. In both cases, DECT suggested monosodium urate deposition in spinal tissues as the cause of their presentation.
    UNASSIGNED: Axial gout should be considered in the differential diagnosis of severe spinal pain. A DECT study may be a useful diagnostic tool in the management of spinal gout.
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  • 文章类型: Case Reports
    Gout is a common form of inflammatory arthritis, and the majority of gout patients experience recurrent acute attacks, joint damage, and other complications. Carpal tunnel syndrome caused by gouty tophi indicates the severity of untreated gouty tophi. In this article, we report a 54-year- old male chronic gout patient with serious carpal tunnel syndrome secondary to monosodium urate crystal deposit. The patient was admitted to our department with palmar numbness and disability for two years. He had a history of gout for 30 years but received no treatment. Multiple monosodium urate crystals were observed to be deposited in and around carpal tunnel on the three-dimensional reconstruction using dual energy computed tomography, which confirmed the diagnosis. The needle biopsy and electrophysiological test also supported the diagnosis. Our case indicates that dual energy computed tomography is a useful method to diagnose carpal tunnel syndrome associated with gout and that we should keep in mind the possibility of gouty tophi as a possible cause of carpal tunnel syndrome.
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