Diabetic Foot

糖尿病足
  • 文章类型: Journal Article
    背景:Charcot神经骨关节病(CNO)是一种罕见但破坏性的糖尿病并发症,与高发病率相关;然而,许多非脚专家都没有意识到这一点,导致漏诊和延误诊断。临床实践指南(CPG)已被证明可用于提高护理质量并规范糖尿病和糖尿病足护理的实践。然而,关于识别和管理活跃CNO的建议的一致性知之甚少。目的:这项研究的目的是回顾欧洲国家糖尿病CPGs对活动性CNO的诊断和管理,并评估其方法学的严密性和透明度。方法:进行了系统的搜索,以确定整个欧洲的糖尿病国家CPG。对任何语言的指南进行了审查,以探讨它们是否为活跃的CNO提供了定义和诊断建议,监测,和管理。方法的严密性和透明度使用评估指南的研究和评价(AGREE-II)工具进行评估,其中包括在六个领域中组织的23个关键项目,总体指南评估得分≥60%,被认为具有足够的推荐使用质量。每个指南都由两名评审员评估,并计算了AGREE-II分数的评分者间协议(肯德尔的W)。结果:17个CPG符合纳入标准。CNO内容的广度因指南而异(中位数(IQR)字数:327;Q1=151;Q3=790),53%提供了活性CNO的定义。82%和53%的人提供了诊断和监测建议,分别,卸载是最常见的管理建议(88%)。四项指南(24%)达到了推荐用于临床实践的阈值(≥60%),范围和目的领域得分最高(平均值(SD):67%,±23%)。其余领域的平均得分在19%和53%之间。评分者之间的一致性很强(W=0.882;p<0.001)。结论:欧洲国家糖尿病CPGs对活性CNO的建议有限。所有指南都显示了其方法的缺陷,建议整个欧洲的糖尿病CPG发展应采用更严格的方法。
    Background: Charcot neuro-osteoarthropathy (CNO) is a rare but devastating complication of diabetes associated with high rates of morbidity; yet, many nonfoot specialists are unaware of it, resulting in missed and delayed diagnosis. Clinical practice guidelines (CPGs) have proven useful in improving quality of care and standardizing practice in diabetes and diabetic foot care. However, little is known about the consistency in recommendations for identification and management of active CNO. Aim: The aim of this study is to review European national diabetes CPGs for the diagnosis and management of active CNO and to assess their methodological rigor and transparency. Methods: A systematic search was performed to identify diabetes national CPGs across Europe. Guidelines in any language were reviewed to explore whether they provided a definition for active CNO and recommendations for diagnosis, monitoring, and management. Methodological rigor and transparency were assessed using the Appraisal of Guidelines for Research and Evaluation (AGREE-II) tool, which comprises 23 key items organized within six domains with an overall guideline assessment score of ≥ 60% considered to be of adequate quality to recommend use. Each guideline was assessed by two reviewers, and inter-rater agreement (Kendall\'s W) was calculated for AGREE-II scores. Results: Seventeen CPGs met the inclusion criteria. Breadth of CNO content varied across guidelines (median (IQR) word count: 327; Q1 = 151; Q3 = 790), and 53% provided a definition for active CNO. Recommendations for diagnosis and monitoring were provided by 82% and 53%, respectively, with offloading being the most common management recommendation (88%). Four guidelines (24%) reached threshold for recommendation for use in clinical practice (≥ 60%) with the scope and purpose domain scoring highest (mean (SD): 67%, ± 23%). The remaining domains had average scores ranging between 19% and 53%. Inter-rater agreement was strong (W = 0.882; p < 0.001). Conclusions: European national CPGs for diabetes provide limited recommendations on active CNO. All guidelines showcased deficits in their methodology, suggesting that more rigorous methods should be employed for diabetes CPG development across Europe.
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  • 文章类型: English Abstract
    .糖尿病足的管理:糖尿病足国际工作组的新指南。糖尿病足新指南的发布是对(少数)新进展进行微调的机会,而是迄今为止已知的证据和知识的合理性。与之前的2019年指南相比,2023年的更新仅包括随机临床试验的分析,更准确地应用等级方法,更精简、更最新的参考书目,以及一些建议的强度从低到有条件的更新。2023年更新的真正重大新闻是发布了诊断和治疗糖尿病患者Charcot神经骨关节病的具体指南,神经病变和没有皮肤损伤。
    . The management of diabetic foot: the new guidelines of the International Working Group on Diabetic Foot. The publication of the new guidelines on the diabetic foot are an opportunity for a fine-tuning of the (few) new developments, but of the soundness of the evidence and knowledge known so far. Compared to the previous 2019 guidelines, the 2023 update included the analysis of randomised clinical trials only, a more accurate application of the GRADE method, a leaner and more current bibliography, and an update of the strength of some recommendations from low to conditional. The real big news in the 2023 update is the publication of a specific guideline for the diagnosis and treatment of Charcot neuro-osteoarthropathy in people with diabetes, neuropathy and in the absence of skin lesions.
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  • 文章类型: Journal Article
    2型糖尿病可导致严重的足部并发症,进行自我保健教育,在临床指南的指导下,至关重要。然而,零散和分散的建议对这些准则的有效实施提出了挑战。将建议汇总在一起并根据自我护理模型提出建议可以提供坚实的框架并促进结果的解释。
    绘制国际指南,向护士提供建议,使2型糖尿病患者能够进行足部自我护理,并根据慢性病自我护理的中程理论的关键概念综合建议。
    进行了范围审查,使用乔安娜·布里格斯研究所的方法论指导。
    在2022年9月至2023年6月之间搜索了数据库,包括PubMed,CINAHL,PsycINFO,Scopus,WebofScience核心合集,ProQuest论文和论文全球,指南网站和相关专业协会网站。选择数据库是为了全面覆盖该地区。
    符合条件的文章包括提供糖尿病足部护理建议的指导文件,在2013年至2023年之间发布或更新。根据自我护理模型的关键概念,两名审阅者总结了至少两个指南中提出的建议。使用PRISMA-ScR检查表。
    包括17条准则。总的来说,我们综合了175条建议。建议分为三个维度及其各自的类别:自我护理维护(预防教育,控制风险因素,日常足部护理,鞋类,和袜子),自我护理监测(足部检查,检测感染迹象,以及检测其他与糖尿病相关的足部疾病并发症),和自我护理管理(对体征和症状的反应,足部伤口护理,与卫生专业人员的后续行动,和卫生服务)。
    足部护理的主要方面围绕日常护理,包括清洁,保湿,指甲护理,选择合适的鞋类,并定期检查双脚和鞋类。
    UNASSIGNED: Type 2 diabetes can lead to severe foot complications, making self-care education, guided by clinical guidelines, crucial. However, fragmented and dispersed recommendations challenge effective implementation of these guidelines. Bringing together recommendations and presenting them according to a self-care model can provide a solid framework and facilitate the interpretation of results.
    UNASSIGNED: to map the international guidelines that provide recommendations to nurses to enable people with type 2 diabetes for foot self-care and synthesize the recommendations according to the key concepts of the middle-range theory of self-care for chronic diseases.
    UNASSIGNED: A scoping review was undertaken, using the methodological guidance of the Joanna Briggs Institute.
    UNASSIGNED: Databases were searched between September 2022 and June 2023, including PubMed, CINAHL, PsycINFO, Scopus, Web of Science Core Collection, ProQuest Dissertations and Theses Global, guideline websites and related professional association websites. The databases were chosen for their comprehensive coverage of the area.
    UNASSIGNED: Eligible articles included guidance documents providing foot care recommendations for diabetes, published or updated between 2013 and 2023. Two reviewers summarized the recommendations presented in at least two guidelines according to the key concepts of the self-care model. The PRISMA-ScR checklist was used.
    UNASSIGNED: Seventeen guidelines were included. In total, we synthesized 175 recommendations. The recommendations were framed in three dimensions and their respective categories: Self-care maintenance (education for prevention, control of risk factors, daily foot care, footwear, and socks), Self-care monitoring (foot inspection, detection of signs of infection, and detection of other diabetes-related foot disease complications), and Self-care management (responses to signs and symptoms, foot wound care, follow-up with health professionals, and health services).
    UNASSIGNED: The main aspect of foot care revolves around daily care, including cleaning, moisturizing, nail care, selecting appropriate footwear, and regular inspection of both feet and footwear.
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  • 文章类型: Journal Article
    糖尿病足与解剖学相互作用,血管,和挑战临床实践的神经因素。本研究旨在基于对主要指南的回顾,汇编主要科学证据。除了在Embase上发表的文章,丁香花,和PubMed平台。欧洲心脏病学会系统用于制定推荐类别和证据水平。主题分为六章(第1章-糖尿病患者足部溃疡的预防;第2章-糖尿病患者足部溃疡的压力缓解;第3章-糖尿病足溃疡的分类;第4章-足部和外周动脉疾病;第5章-感染和糖尿病足;第6章-Charcot神经关节病)。这个版本的糖尿病足指南提出了预防的基本建议,诊断,治疗,以及糖尿病足患者的随访,为医学实践提供客观指导。
    The diabetic foot interacts with anatomical, vascular, and neurological factors that challenge clinical practice. This study aimed to compile the primary scientific evidence based on a review of the main guidelines, in addition to articles published on the Embase, Lilacs, and PubMed platforms. The European Society of Cardiology system was used to develop recommendation classes and levels of evidence. The themes were divided into six chapters (Chapter 1 - Prevention of foot ulcers in people with diabetes; Chapter 2 - Pressure relief from foot ulcers in people with diabetes; Chapter 3 -Classifications of diabetic foot ulcers; Chapter 4 - Foot and peripheral artery disease; Chapter 5 - Infection and the diabetic foot; Chapter 6 - Charcot\'s neuroarthropathy). This version of the Diabetic Foot Guidelines presents essential recommendations for the prevention, diagnosis, treatment, and follow-up of patients with diabetic foot, offering an objective guide for medical practice.
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  • 文章类型: Journal Article
    在这个播客中,我们讨论了国际糖尿病足工作组(IWGDF)糖尿病患者足部溃疡预防指南2023年的更新.预防足部溃疡至关重要,减轻患者和社会的巨大负担。然而,许多临床指南没有将预防作为主题.IWGDF指南确保有完整的章节专门讨论溃疡预防。在这一章中,概述了预防的关键基石,以及综合预防性足部护理的重要性。有了这个播客,我们的目标是强调预防溃疡的重要性,以及将建议纳入临床实践的机会。这有望刺激临床医生和研究人员增加对糖尿病足溃疡预防的关注。本文提供了播客音频。
    In this podcast, we discuss the 2023 update of the International Working Group on the Diabetic Foot (IWGDF) Guidelines on the prevention of foot ulcers in people with diabetes. Prevention of foot ulcers is paramount, to reduce their large burden on patients and society. Nevertheless, many clinical guidelines do not cover prevention as a topic. The IWGDF Guidelines ensure that a full chapter is dedicated to ulcer prevention. In that chapter, the key cornerstones of prevention are outlined, as well as the importance of integrated preventative foot care. With this podcast, we aim to highlight the importance of ulcer prevention and the opportunities to incorporate recommendations into clinical practice. This hopefully stimulates clinicians and researchers to increase focus on ulcer prevention in diabetic foot disease.A podcast audio is available with this article.
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  • 文章类型: English Abstract
    Diabetic foot ulcers complicated with lower extremity vasculopathy possess the characteristics of high incidence, slow healing, and poor prognosis, which may eventually lead to amputation or even life-threatening if not treated properly. The treatment of complicated lower extremity vasculopathy is vital to improve the healing process of diabetic foot ulcers, which has gradually received attention in clinical practice. Recently, a number of clinical trials on diabetic foot ulcers complicated with lower extremity vasculopathy were reported. In order to further standardize the clinical diagnosis and treatment of diabetic foot ulcers complicated with lower extremity vasculopathy, an expert group headed by Burns and Trauma Branch of Chinese Geriatrics Society, Chinese Burn Association, and Wound Repair Professional Committee of Chinese Medical Doctor Association deliberated and compiled the National expert consensus on the diagnosis and surgical treatment of diabetic foot ulcers complicated with lower extremity vasculopathy (2024 version) together. This consensus is based on evidences from the literature, covers the disease characteristics, evidence-based evidence of clinical diagnosis and treatment, as well as the application of new technologies and new treatment approaches of diabetic foot ulcers complicated with lower extremity vasculopathy. The goal of this consensus is to provide clear guidance to practitioners on the best approaches for screening, diagnosing, and treating diabetic foot ulcers complicated with lower extremity vasculopathy in individuals, hoping to provide a normative clinical practice basis for medical staff engaged in the treatment of diabetic foot wounds.
    糖尿病足溃疡合并下肢血管病变具有发病率高、愈合缓慢、预后差的特点,如不经规范治疗易导致截肢甚至危及生命。针对合并下肢血管病变的治疗对改善糖尿病足溃疡的愈合进程至关重要,在临床实践中逐渐得到重视。近年来,关于糖尿病足溃疡合并下肢血管病变的临床研究已见诸多报道,为了进一步规范临床诊疗,由中国老年医学学会烧创伤分会、中华医学会烧伤外科学分会、中国医师协会创面修复专业委员会牵头的专家组共同审议并编写了《糖尿病足溃疡合并下肢血管病变的外科诊疗全国专家共识(2024版)》。该共识以文献证据为基础,内容涵盖了糖尿病足溃疡合并下肢血管病变的疾病特征、临床诊疗循证证据以及新技术和新治疗方法的应用,旨在为临床工作者提供关于糖尿病足溃疡合并下肢血管病变最佳筛查和诊疗方法的明确指导,希望为从事糖尿病足创面治疗的医务人员提供规范性的临床实践依据。.
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  • 文章类型: Journal Article
    关于糖尿病相关足部感染的诊断和治疗的IWGDF/IDSA指南发布日期:2023年10月2日之前版本:2020年3月16日开发者:IWGDF编辑委员会资金来源:糖尿病足国际工作组(IWGDF),美国传染病学会(IDSA)目标群体:疑似或确诊糖尿病相关足部感染的成年人。
    UNASSIGNED: IWGDF/IDSA Guidelines on the Diagnosis and Treatment of Diabetes-related Foot Infections RELEASE DATE: October 2, 2023 PRIOR VERSION: March 16, 2020 DEVELOPER: IWGDF Editorial Board FUNDING SOURCE: International Working Group on the Diabetic Foot (IWGDF), Infectious Diseases Society of America (IDSA) TARGET POPULATION: Adults with suspected or confirmed diabetes-related foot infections.
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  • 文章类型: Journal Article
    在这个播客中,2023年国际糖尿病足工作组(IWGDF)糖尿病相关足部溃疡卸载治疗指南的主要作者简要讨论了为什么我们需要对糖尿病相关足部溃疡患者进行卸载治疗,新的国际卸载指南建议,以及未来卸载治疗可能会在哪里进行。本文提供了播客音频。
    In this podcast the lead authors of the 2023 International Working Group on the Diabetic Foot (IWGDF) guideline on offloading treatments for diabetes-related foot ulcers briefly discuss why we need offloading treatments for people with diabetes-related foot ulcers, what the new international offloading guideline recommends, and where offloading treatment might go into the future.A podcast audio is available with this article.
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  • 文章类型: Journal Article
    背景:在这个播客中,我们介绍了国际糖尿病足工作组(IWGDF)2019年指南2023年计划更新的结果,该指南涉及在常规临床实践中使用系统对糖尿病患者足部溃疡进行分类.
    方法:这些指南基于对现有文献的系统回顾,这些文献确定了149篇文章中涉及的28种分类,随后,使用建议分级的专家意见,评估,发展,和评价(等级)方法。我们首先独立评估每个系统的价值,在第二阶段,选择最好的一种或两种用于每种临床方案。
    结果:我们建议(1)医疗保健专业人员之间的沟通使用本网站,缺血,神经病,细菌感染,区域,深度(SINBAD)分类(第一选项)或考虑使用伤口,缺血,足部感染(WIfI)系统(备选方案,当可用所需的设备和专业知识水平并且认为可行时),并且在每种情况下,应描述构成系统的各个变量而不是总分;(2)用于预测特定个体的溃疡结果:不建议使用现有系统;(3)用于表征患有感染溃疡的人:使用IDSA(美国感染疾病协会)/IWGDF(第一选项)分类或考虑使用WfI选项当具备所需的设备和专业知识水平并且认为可行时);(4)对患有外周动脉疾病的人进行表征:考虑使用WIfI系统作为对治愈可能性和截肢风险进行分层的方法;(5)对人群的结局进行审核:使用SINBAD评分。
    结论:尽管没有适合所有目的的分类,至关重要的是,医疗保健专业人员应使用经过验证的分类系统来规范他们对糖尿病相关足部溃疡的表征方式,并指导他们的决策过程。
    BACKGROUND: In this podcast, we present the result of the 2023 scheduled update of the 2019 guidelines of the International Working Group of the Diabetic Foot (IWGDF) addressing the use of systems to classify foot ulcers in people with diabetes in routine clinical practice.
    METHODS: These guidelines were based on a systematic review of the available literature that identified 28 classifications addressed in 149 articles and, subsequently, expert opinion using the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) methodology. We first assessed the value of each system independently and, in the second stage, chose the best one or two to be used in each clinical scenario.
    RESULTS: We recommend (1) for communication among healthcare professionals to use the Site, Ischaemia, Neuropathy, Bacterial infection, Area, Depth (SINBAD) classification (first option) or consider using Wound, Ischaemia, foot Infection (WIfI) system (alternative option, when the required equipment and level of expertise are available and it is considered feasible) and in each case the individual variables that compose the systems should be described rather than a total score; (2) for predicting the outcome of an ulcer in a specific individual: no existing system could be recommended; (3) for characterising a person with an infected ulcer: the use of the IDSA (Infection Diseases Society of America)/IWGDF (first option) classification or consider using the WIfI system (alternative option, when the required equipment and level of expertise are available and it is considered as feasible); (4) for characterising a person with peripheral artery disease: consider using the WIfI system as a means to stratify healing likelihood and amputation risk; (5) for the audit of outcome(s) of populations: the use of the SINBAD score.
    CONCLUSIONS: Although there is no classification that fits all purposes, it is crucial that healthcare professionals standardize the way they characterise diabetes-related foot ulcers and guide their decision-making process by using validated classification systems.
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  • 文章类型: Journal Article
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