在过去的十年里,大脑的振荡反应已经侵入了文献。应用认知范式对人类delta(0.5-3.5Hz)振荡反应的研究表明,delta振荡与认知过程有关,主要在决策和注意过程中。本手稿全面回顾了健康受试者和不同病理中认知刺激后的delta振荡反应的研究,即阿尔茨海默病,轻度认知障碍(MCI),双相情感障碍,精神分裂症和酗酒。面部呈现时进一步的三角洲振荡反应,面部表情,和情感图片进行审查。讨论了刺激前delta活动与刺激后诱发和事件相关的反应和/或振荡之间的关系。该综述还包括具有较高频率窗口的delta振荡的交叉频率耦合。这篇综述的结论包括几个重要的评论,包括三角洲振荡反应参与认知和情绪过程。δ振荡反应的减少可能是认知功能障碍的一般电生理标志物(阿尔茨海默病,MCI双相情感障碍,精神分裂症和酒精中毒)。刺激前活动(delta活动的相位或幅度变化)对刺激后EEG响应有影响。
In the last decade, the brain\'s oscillatory responses have invaded the literature. The studies on delta (0.5-3.5Hz) oscillatory responses in humans upon application of cognitive paradigms showed that delta oscillations are related to cognitive processes, mainly in decision making and attentional processes. The present manuscript comprehensively reviews the studies on delta oscillatory responses upon cognitive stimulation in healthy subjects and in different pathologies, namely Alzheimer\'s disease, Mild Cognitive Impairment (MCI), bipolar disorder, schizophrenia and alcoholism. Further delta oscillatory response upon presentation of faces, facial expressions, and affective pictures are reviewed. The relationship between pre-stimulus delta activity and post-stimulus evoked and event-related responses and/or oscillations is discussed. Cross-frequency couplings of delta oscillations with higher frequency windows are also included in the
review. The conclusion of this
review includes several important remarks, including that delta oscillatory responses are involved in cognitive and emotional processes. A decrease of delta oscillatory responses could be a general electrophysiological marker for cognitive dysfunction (Alzheimer\'s disease, MCI, bipolar disorder, schizophrenia and alcoholism). The pre-stimulus activity (phase or amplitude changes in delta activity) has an effect on post-stimulus EEG responses.