Delayed ejaculation

延迟射精
  • 文章类型: Journal Article
    背景:与勃起功能障碍(ED)相比,射精功能障碍(EjD)是一种复杂的病理状况。EjD的明确分类尚未建立,治疗往往会延迟。由于它与不孕症有关,EjD是一个严重的问题,特别是在育龄男性中。
    方法:作者进行了文献检索,以确定最新的文章和国外指南以供审查。
    结果:我们的新分类将男性分为以下两组:(1)无法射精的男性(逆行射精,射精,阴道内射精功能障碍)和(2)需要射精时间异常的男性(早泄,延迟射精)。在日本,无法射精的男性人数多于早泄的男性。药物治疗是这些EjD患者的一线治疗。根据情况,将行为疗法添加到药物疗法中。阴茎振动刺激或电射精适用于一些逆行射精和射精的男性。如果希望有孩子,辅助生殖技术应同时考虑不要浪费时间。
    结论:区分EjD和ED并准确诊断EjD的类型对于这种疾病的最佳治疗非常重要。
    BACKGROUND: Ejaculatory dysfunction (EjD) is a complex pathological condition compared to erectile dysfunction (ED). A definitive classification of EjD is not established, and treatment is often delayed. Owing to its association with infertility, EjD is a serious concern, particularly in men of reproductive age.
    METHODS: The authors performed a literature search to identify the latest articles and overseas guidelines for review.
    RESULTS: Our new classification categorizes men into two groups as follows: (1) men with inability to ejaculate (retrograde ejaculation, anejaculation, intravaginal ejaculatory dysfunction) and (2) men requiring an abnormal time for ejaculation (premature ejaculation, delayed ejaculation). In Japan, the number of men presenting with an inability to ejaculate is greater than those presenting with premature ejaculation. Pharmacotherapy is the first-line treatment for the management of these EjD patients. Behavioral therapy is added to pharmacotherapy depending on the case. Penile vibratory stimulation or electroejaculation is indicated in some men with retrograde ejaculation and anejaculation. In cases who hope for a baby, assisted reproductive technology should be simultaneously considered not to waste time.
    CONCLUSIONS: It is important to distinguish between EjD and ED and accurately diagnose the type of EjD for optimal treatment of this condition.
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  • 文章类型: Journal Article
    This paper reviews the associations between pornography use and sexual dysfunction based on evidence from observational studies. The existing data in this regard mostly derive from cross-sectional investigations and case reports. There is little if no evidence that pornography use may induce delayed ejaculation and erectile dysfunction, although longitudinal studies that control for confounding variables are required for a full assessment. The associations between pornography use and sexual desire may differ between women and men although the existing data is contradictory and causal relationships cannot be established. The strongest evidence is available for the relation of pornography use with decreased sexual satisfaction, although the results of prospective studies are inconsistent. The paper outlines future research prospects beneficial in understanding the nature of associations between pornography use and sexual dysfunctions in men and women.
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  • 文章类型: Journal Article
    Sexual dysfunction is an underdiscussed adverse effect to selective serotonin reuptake inhibitors (SSRIs) and may increase the risk for discontinuation and nonadherence to antidepressant pharmacotherapy. Given the prevalence of depression, health care providers should educate patients about SSRI-associated sexual dysfunction in order to promote patient awareness and medication adherence. This study evaluated primary literature from 1997 to 2015 to identify SSRI-related sexual side effects, therapeutic alternatives, and treatment strategies. The results indicate that paroxetine is associated with the greatest rate of sexual dysfunction among the SSRIs. Potential alternatives to SSRI treatment include bupropion, mirtazapine, vilazodone, vortioxetine, and serotonin-norepinephrine reuptake inhibitors. In the event that a subject responds solely to SSRIs but experiences unwanted sexual side effects, bupropion may be added as an adjunctive medication. Some limited evidence also suggests that saffron may reduce some aspects of sexual dysfunction, excluding ability to reach orgasm.
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  • 文章类型: Journal Article
    Delayed ejaculation (DE) is a poorly defined disorder that entails the delay or absence of orgasm that results in personal distress. Numerous causes of DE exist, and management must be tailored to the specific etiology to maximize treatment success. Management strategies include psychological and sexual therapy, pharmacotherapy, and penile vibratory stimulation.
    This article intends to review the pathophysiology and treatment options for DE discussed in the literature to date.
    A review of the literature was performed to identify and evaluate the existing data on treatment success for the various forms of DE management.
    Each treatment option was evaluated for method of administration, data supporting its success for DE, and potential risks or side effects.
    Different psychosexual therapy strategies have been described for DE but with limited data to describe efficacy. There is no medication for DE approved by the United States Food and Drug Administration. The quality of evidence supporting the off-label use of medications for DE is low. However, there are numerous medications reported in the literature suggested to treat the condition. Cabergoline and bupropion are the two most commonly used. In addition, penile vibratory stimulation has been described as an adjunct treatment option for DE.
    There are different treatment options reported for DE, all with limited evidence supporting their efficacy. Identifying the etiology of the DE is important to appropriately target therapy. A multimodal approach combining psychosexual therapy with medications and/or penile vibratory stimulation will likely provide the best outcomes.
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  • 文章类型: Journal Article
    曾经解释男性性困难的传统因素似乎不足以解释勃起功能障碍的急剧上升,延迟射精,性满意度下降,40岁以下男性的性伴侣性欲下降。这篇评论(1)考虑了来自多个领域的数据,例如,临床,生物学(成瘾/泌尿科),心理(性条件),社会学;(2)提出了一系列临床报告,目的是为这一现象的未来研究提出一个可能的方向。大脑动机系统的改变被探索为色情相关性功能障碍的可能病因。这篇评论还考虑了互联网色情的独特属性(无限新颖性,容易升级到更极端材料的潜力,视频格式,等。)可能足以使性唤起成为互联网色情使用中不易过渡到现实生活中的伴侣的方面,这样,与所需伴侣的性行为可能不会注册为满足期望和唤醒下降。临床报告表明,终止网络色情使用有时足以扭转负面影响,强调需要使用方法进行广泛的调查,这些方法可以使主题消除互联网色情使用的变量。在此期间,提出了一种简单的诊断方案,用于评估色情引起的性功能障碍患者。
    Traditional factors that once explained men\'s sexual difficulties appear insufficient to account for the sharp rise in erectile dysfunction, delayed ejaculation, decreased sexual satisfaction, and diminished libido during partnered sex in men under 40. This review (1) considers data from multiple domains, e.g., clinical, biological (addiction/urology), psychological (sexual conditioning), sociological; and (2) presents a series of clinical reports, all with the aim of proposing a possible direction for future research of this phenomenon. Alterations to the brain\'s motivational system are explored as a possible etiology underlying pornography-related sexual dysfunctions. This review also considers evidence that Internet pornography\'s unique properties (limitless novelty, potential for easy escalation to more extreme material, video format, etc.) may be potent enough to condition sexual arousal to aspects of Internet pornography use that do not readily transition to real-life partners, such that sex with desired partners may not register as meeting expectations and arousal declines. Clinical reports suggest that terminating Internet pornography use is sometimes sufficient to reverse negative effects, underscoring the need for extensive investigation using methodologies that have subjects remove the variable of Internet pornography use. In the interim, a simple diagnostic protocol for assessing patients with porn-induced sexual dysfunction is put forth.
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