Deglutition disorders

吞咽障碍
  • 文章类型: Journal Article
    背景:在重症监护病房(ICU)气管内插管后,拔管后吞咽困难(PED)是一种常见的并发症。PED与不良后果密切相关,包括抽吸,肺炎,营养不良,死亡率上升,和长期住院,导致医疗支出增加。然而,报告的PED发病率在现有文献中差异很大.因此,本综述的主要目的是对接受经口气管插管的ICU患者的PED发生率进行综合评估.
    方法:我们搜索了Embase,PubMed,WebofScience,科克伦图书馆,中国国家知识基础设施(CNKI),万方数据库,中国科学,科技期刊数据库(VIP),和SinoMed数据库从成立到2023年8月。两名评审员独立筛选研究并提取数据。随后,利用StataSE15.0版中的"metaprop"命令,采用随机效应模型进行荟萃统计分析,以确定PED的发生率.此外,我们进行了亚组分析和荟萃回归,以阐明纳入研究的异质性的潜在来源.
    结果:在4144项研究中,本综述包括30项研究。PED的总体合并发生率为36%(95%置信区间[CI]29-44%)。亚组分析揭示了PED的合并发病率,按评估时间分层(≤3小时,4-6小时,≤24h,且≤48h),如下:31.0%(95%CI8.0-59.0%),28%(95%CI22.0-35.0%),41%(95%CI33.0-49.0%),和49.0%(95%CI34.0-63.0%),分别。当样本量为100结论:在接受经口气管插管的ICU患者中,PED的发生率较高。ICU专业人员应提高对PED的认识。同时,对于准确评估PED的发生率,必须就最合适的PED评估时间和评估工具制定指南或达成共识.
    BACKGROUND: Post-extubation dysphagia (PED) emerges as a frequent complication following endotracheal intubation within the intensive care unit (ICU). PED has been strongly linked to adverse outcomes, including aspiration, pneumonia, malnutrition, heightened mortality rates, and prolonged hospitalization, resulting in escalated healthcare expenditures. Nevertheless, the reported incidence of PED varies substantially across the existing body of literature. Therefore, the principal objective of this review was to provide a comprehensive estimate of PED incidence in ICU patients undergoing orotracheal intubation.
    METHODS: We searched Embase, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, China Science, Technology Journal Database (VIP), and SinoMed databases from inception to August 2023. Two reviewers independently screened studies and extracted data. Subsequently, a random-effects model was employed for meta-statistical analysis utilizing the \"meta prop\" command within Stata SE version 15.0 to ascertain the incidence of PED. In addition, we performed subgroup analyses and meta-regression to elucidate potential sources of heterogeneity among the included studies.
    RESULTS: Of 4144 studies, 30 studies were included in this review. The overall pooled incidence of PED was 36% (95% confidence interval [CI] 29-44%). Subgroup analyses unveiled that the pooled incidence of PED, stratified by assessment time (≤ 3 h, 4-6 h, ≤ 24 h, and ≤ 48 h), was as follows: 31.0% (95% CI 8.0-59.0%), 28% (95% CI 22.0-35.0%), 41% (95% CI 33.0-49.0%), and 49.0% (95% CI 34.0-63.0%), respectively. When sample size was 100 < N ≤ 300, the PED incidence was more close to the overall PED incidence. Meta-regression analysis highlighted that sample size, assessment time and mean intubation time constituted the source of heterogeneity among the included studies.
    CONCLUSIONS: The incidence of PED was high among ICU patients who underwent orotracheal intubation. ICU professionals should raise awareness about PED. In the meantime, it is important to develop guidelines or consensus on the most appropriate PED assessment time and assessment tools to accurately assess the incidence of PED.
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  • 文章类型: Journal Article
    背景:口咽吞咽困难(OD)难以从口腔到喉咙操纵食物推注。高达70%的老年人发展OD;然而,它在初级保健中得不到管理,导致可避免的住院。
    目的:本行为科学现实主义者综述旨在开发计划理论,以描述干预措施如何促进初级保健医疗保健专业人员(HCP)主动管理OD。
    方法:我们利用利益相关者的专业知识和理论领域框架(TDF),归纳地开发了初始计划理论(IPT)。搜索数据库以识别有关上下文的证据,与积极管理OD和提供可转移学习的比较行为相关的行为机制和结果。IPT经过测试,有证据证实,提炼或反驳,产生最终的方案理论。
    结果:包括36个证据来源。产生了五个最终计划理论,解释了如何促进初级保健HCP主动管理OD:(1)OD教育和培训,(2)有OD体征和症状的检查表,(3)将OD识别纳入现有工作流程,(4)使HCP意识到老年人和护理人员期望他们管理OD;(5)提高对OD不良后果的认识。
    结论:五种计划理论提供了行为机制,通过这些机制,干预措施可以促进初级保健HCP主动管理OD。通过程序理论与TDF的联系,可以选择映射到相关TDF域的行为改变技术(BCT)进行干预。应使用共同设计方法将选定的BCT操作成连贯的干预方案。
    CRD42022320327。
    BACKGROUND: Oropharyngeal dysphagia (OD) is difficulty manipulating a food bolus from the mouth to the throat. Up to 70% of older adults develop OD; however, it is unmanaged in primary care, leading to avoidable hospitalisation.
    OBJECTIVE: This behavioural science realist review aimed to develop programme theories to describe how interventions facilitate primary care healthcare professionals (HCPs) to proactively manage OD.
    METHODS: We developed initial programme theories (IPTs) inductively using the expertise of stakeholders and deductively using the theoretical domains framework (TDF). Databases were searched to identify evidence regarding contexts, behavioural mechanisms and outcomes related to proactive management of OD and comparative behaviours which offer transferrable learning. IPTs were tested with the evidence to confirm, refine or refute, to produce final programme theories.
    RESULTS: 36 sources of evidence were included. Five final programme theories were generated explaining how primary care HCPs can be facilitated to proactively manage OD: (1) OD education and training, (2) checklists with OD signs and symptoms, (3) incorporating OD identification into existing workflow, (4) making HCPs aware that older adults and carers expect them to manage OD and (5) raising awareness of the adverse outcomes of OD.
    CONCLUSIONS: The five programme theories provide the behavioural mechanisms by which an intervention may facilitate primary care HCPs to proactively manage OD. Through the programme theories\' linkage to the TDF, behaviour change techniques (BCTs) mapped to the relevant TDF domain can be selected for an intervention. Operationalisation of selected BCTs into a coherent intervention package should be undertaken using codesign methodology.
    UNASSIGNED: CRD42022320327.
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  • 文章类型: Journal Article
    随着康复服务提供者之间跨学科交流的扩大,已经引入了治疗吞咽障碍的新技术。Kinesio录音(KT)是最近引起人们注意的吞咽和进食障碍康复技术之一。鉴于这项技术在研究和实践中的新颖性,本范围综述旨在总结KT对吞咽相关口咽功能影响的现有证据,并确定当前的知识差距,以指导未来的研究。最初的全面搜索于2022年11月在六个数据库中进行,然后于2023年6月进行更新。研究由两位作者独立审查,以排除所有类型的审查和研究方案。仅以抽象形式发表的研究以及使用KT改善声音和构音障碍症状的研究。两位作者还使用JoannaBriggs研究所(JBI)标准工具对纳入研究的方法进行了严格评估。根据研究的总体目标对研究结果进行分类和报告。归根结底,描述了21篇文章。研究设计范围从随机对照试验(RCT)到病例报告。已经研究了KT对流口水的影响,婴儿经口喂养技巧,立即激活吞咽肌肉,中风或脑瘫(CP)患者吞咽困难的管理。尽管在研究中已经研究了使用KT作为吞咽障碍治疗方法的创新方法,有许多方法上的限制影响了结果的有效性。总的来说,似乎还没有足够的证据将KT添加到喂养和吞咽障碍的常规管理中。进一步研究,因此,需要在本研究总结的每个目标中获得更准确的结论。
    Following the expansion of interdisciplinary communication among rehabilitative service providers, new techniques have been introduced for treating swallowing disorders. Kinesio taping (KT) is one of the recently noticed techniques in the rehabilitation of swallowing and feeding disorders. Given the novelty of this technique in research and practice, the present scoping review aimed to summarize the available evidence on the effects of KT on the oropharyngeal function related to swallowing, and to identify current knowledge gaps to guide future studies. The initial comprehensive search was conducted in the six databases in November 2022 and then was updated in June 2023. Studies were independently reviewed by two authors to exclude all types of reviews and study protocols, studies published only in an abstract form and also studies that used KT for improving voice and dysarthria symptoms. The methodology of the included studies was also critically appraised using Joanna Briggs Institute (JBI) standard tools by two authors. The results of the studies were categorized and reported based on their overall objectives. In final analysis, 21 articles were described. Study designs ranged from randomized control trials (RCTs) to the case reports. The effects of KT had been investigated on drooling, oral feeding skills of infants, immediate activation of swallowing muscles, and management of dysphagia in patients with stroke or cerebral palsy (CP). Although innovative approaches to use KT as a therapeutic method in swallowing disorders have been investigated in the studies, there are many methodological limitations that affected validity of the results. In general, it seems there is not enough evidence to add KT to the usual management of feeding and swallowing disorders yet. Further studies, therefore, are required to achieve more accurate conclusions in each of the objectives summarized in this study.
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  • 文章类型: Journal Article
    目的:吞咽困难常见于后颅窝肿瘤(PFT)切除的个体,对个体的生活质量产生负面影响,营养状况,和整体健康。我们旨在定量综合PFT切除术后吞咽困难患病率研究的数据。
    方法:PubMed,WebofScience,Cochrane图书馆,Embase,中国国家知识基础设施(CNKI),万方数据库,我们在VIP数据库中搜索了评估PFT术后吞咽困难患病率的病例对照和横断面研究.进行荟萃分析以确定吞咽困难的患病率。进行亚组和荟萃回归分析以确定研究中异质性的来源。
    结果:共纳入22项研究,涉及20921例。随机效应模型的荟萃分析显示,PFT切除术后吞咽困难的合并全球患病率为21.7%(95%置信区间:16.9-26.6)。亚组和荟萃回归分析表明,参与者年龄(P<0.001),评估方法(P=0.004),和研究参与者的地理区域(P=0.001)是研究中异质性的来源.
    结论:PFT切除后吞咽困难的患病率很高。应通过筛查及早发现吞咽困难高风险的PFTs个体。需要对吞咽困难进行多学科诊断和治疗,以改善PFT切除术后早期的预后。
    OBJECTIVE: Dysphagia is common in individuals who have undergone posterior fossa tumor (PFT) resection and negatively impacts on the individual\'s quality of life, nutritional status, and overall health. We aimed to quantitatively synthesize data from studies of the prevalence of dysphagia following PFT resection.
    METHODS: PubMed, Web of Science, the Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), Wanfang database, and VIP database were searched for case-control and cross-sectional studies that evaluated the prevalence of dysphagia after PFT surgery. Meta-analyses were performed to determine the prevalence of dysphagia. Subgroup and meta-regression analyses were performed to determine the sources of heterogeneity among the studies.
    RESULTS: A total of 22 studies were included, involving 20,921 cases. A meta-analysis of the random-effects model showed that the pooled global prevalence of dysphagia following PFT resection was 21.7% (95% confidence interval: 16.9-26.6). The subgroup and meta-regression analyses demonstrated that participant age (P < 0.001), assessment methods (P = 0.004), and geographical region of the study participants (P = 0.001) were sources of heterogeneity among the studies.
    CONCLUSIONS: Dysphagia has a high prevalence following PFT resection. Individuals with PFTs who are at a high risk for dysphagia should be identified early through screening. Multidisciplinary diagnosis and treatment of dysphagia are required to improve the outcomes in the early stages after PFT resection.
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  • 文章类型: Journal Article
    中风的特点是“三高”,和吞咽困难是中风后常见的功能障碍。虽然有些患者可以随着病程的延长逐渐从吞咽困难中恢复,在疾病的早期阶段容易因并发症而改变患者的预后,临床研究表明,压针埋针可以改善卒中后吞咽困难患者的预后。对近年来有关压针和埋针治疗脑卒中后吞咽困难的临床相关文献进行综述。压针包埋的应用可以改善中风后的吞咽功能,并产生更显著的影响,这可以改变患者的临床结果。压针埋线治疗脑卒中后吞咽困难具有显著的临床优势,可以改善患者的预后。
    Stroke is characterized by \"three highs,\" and dysphagia is a common dysfunction after stroke. Although some patients can gradually recover from dysphagia with the prolongation of the course of the disease, it is easy to change the prognosis of patients due to complications in the early stage of the disease, and clinical research has shown that pressing needle embedding needles can improve the outcome of patients with dysphagia after stroke. We reviewed the clinical related literature on the treatment of dysphagia after stroke by pressing needle and embedding needle in recent years. The application of press needle embedding can improve swallowing function after stroke, and have more significant effects, which can change the clinical outcome of patients. Pressing needle embedding has significant clinical advantages in the treatment of dysphagia after stroke, which can improve the prognosis of patients.
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  • 文章类型: Systematic Review
    背景:饮食,饮酒和吞咽困难是OA/TOF患者出生时常见的疾病.这项研究旨在确定饮食的性质和患病率,据报道,该人群饮酒和口咽吞咽困难。
    方法:进行系统评价和meta比例分析(PROSPERO:CRD42020207263)。MEDLINE,EMBASE,CINAHL,Pubmed,Scopus,检索了WebofScience数据库和灰色文献。提取与吞咽损伤相关的定量和定性数据,使用进餐时间适应和饮食相关的生活质量。使用叙述和元比例分析方法对定量数据进行汇总。使用元聚合方法合成定性数据。如果定量和定性数据描述了相同的现象,采用收敛分离的方法来合成数据。
    结果:纳入65项研究。确定了六个口咽吞咽特征,和汇总患病率计算:误吸(24%),喉渗透(6%),口腔期功能障碍(11%),咽部残留物(13%),鼻反流(7%),延迟吞咽开始(31%)。确定了四个患者报告的饮食/饮料困难,和汇总患病率计算:吞咽困难固体(45%),吞咽困难的液体(6%),吞咽困难(30%),吃饭时咳嗽(38%)。确定了三个患者报告的进餐时间适应,和汇总患病率计算:进食时需要水(49%),慢慢吃(37%)修改纹理(28%)。心理社会影响的混合方法综合确定了34%的父母经历了进餐时间焦虑,25%的父母报告了具有挑战性的进餐时间行为,反映在五个定性主题中:与饮食相关的恐惧和创伤,孤立和缺乏支持,意识到和感激,支持应对和损失。
    结论:进食和饮料困难在OA/TOF修复的成人和儿童中很常见。口咽吞咽困难可能比以前报道的更普遍。吃,饮酒和吞咽困难会影响心理健康和生活质量,对于个人和父母/家庭成员。长期的,有必要采取多学科的后续行动。
    BACKGROUND: Eating, drinking and swallowing difficulties are commonly reported morbidities for individuals born with OA/TOF. This study aimed to determine the nature and prevalence of eating, drinking and oro-pharyngeal swallowing difficulties reported in this population.
    METHODS: A systematic review and meta-proportional analysis were conducted (PROSPERO: CRD42020207263). MEDLINE, EMBASE, CINAHL, Pubmed, Scopus, Web of Science databases and grey literature were searched. Quantitative and qualitative data were extracted relating to swallow impairment, use of mealtime adaptations and eating and drinking-related quality of life. Quantitative data were summarised using narrative and meta-proportional analysis methods. Qualitative data were synthesised using a meta-aggregation approach. Where quantitative and qualitative data described the same phenomenon, a convergent segregated approach was used to synthesise data.
    RESULTS: Sixty-five studies were included. Six oro-pharyngeal swallow characteristics were identified, and pooled prevalence calculated: aspiration (24%), laryngeal penetration (6%), oral stage dysfunction (11%), pharyngeal residue (13%), nasal regurgitation (7%), delayed swallow initiation (31%). Four patient-reported eating/drinking difficulties were identified, and pooled prevalence calculated: difficulty swallowing solids (45%), difficulty swallowing liquids (6%), odynophagia (30%), coughing when eating (38%). Three patient-reported mealtime adaptations were identified, and pooled prevalence calculated: need for water when eating (49%), eating slowly (37%), modifying textures (28%). Mixed methods synthesis of psychosocial impacts identified 34% of parents experienced mealtime anxiety and 25% report challenging mealtime behaviours reflected in five qualitative themes: fear and trauma associated with eating and drinking, isolation and a lack of support, being aware and grateful, support to cope and loss.
    CONCLUSIONS: Eating and drinking difficulties are common in adults and children with repaired OA/TOF. Oro-pharyngeal swallowing difficulties may be more prevalent than previously reported. Eating, drinking and swallowing difficulties can impact on psychological well-being and quality of life, for the individual and parents/family members. Long-term, multi-disciplinary follow-up is warranted.
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  • 文章类型: Journal Article
    呼吸和球功能障碍(包括吞咽,喂养,和言语功能)是脊髓性肌萎缩症(SMA)的主要症状,尤其是最严重的形式。证明疾病修饰疗法(DMT)的长期疗效需要了解SMA自然史。
    这项研究总结了已发表的关于呼吸,吞咽,喂养,未接受DMT的SMA患者的语音功能。
    电子数据库(Embase,MEDLINE,和循证医学评论)从数据库开始到2022年6月27日进行搜索,以获取报告1-3型SMA中呼吸和/或球功能结局数据的研究。将数据提取到预定义的模板中,并提供了这些数据的描述性摘要。
    包括91种出版物:43种关于呼吸系统的报告数据,吞咽,喂养,和/或言语功能结果。数据强调了1型SMA患者呼吸功能的早期丧失,通常需要12个月大的通气支持。2型或3型SMA患者随着时间的推移有失去呼吸功能的风险,在生命的第一个和第五个十年之间开始通气支持。吞咽和进食困难,包括窒息,咀嚼问题,和愿望,在SMA光谱中的患者中报告。吞咽和进食困难,需要非口服营养支持,在1岁之前报告了1型SMA,在2型SMA的10岁之前。整理了与其他bulbar功能有关的有限数据。
    自然史数据表明,未经治疗的SMA患者呼吸和延髓功能恶化,与更严重的疾病相关的更快的下降。本研究提供了SMA中Bulbar功能的自然历史数据的综合存储库,它强调了对该领域结局的一致评估对于理解和批准新疗法是必要的。
    UNASSIGNED: Respiratory and bulbar dysfunctions (including swallowing, feeding, and speech functions) are key symptoms of spinal muscular atrophy (SMA), especially in its most severe forms. Demonstrating the long-term efficacy of disease-modifying therapies (DMTs) necessitates an understanding of SMA natural history.
    UNASSIGNED: This study summarizes published natural history data on respiratory, swallowing, feeding, and speech functions in patients with SMA not receiving DMTs.
    UNASSIGNED: Electronic databases (Embase, MEDLINE, and Evidence-Based Medicine Reviews) were searched from database inception to June 27, 2022, for studies reporting data on respiratory and/or bulbar function outcomes in Types 1-3 SMA. Data were extracted into a predefined template and a descriptive summary of these data was provided.
    UNASSIGNED: Ninety-one publications were included: 43 reported data on respiratory, swallowing, feeding, and/or speech function outcomes. Data highlighted early loss of respiratory function for patients with Type 1 SMA, with ventilatory support typically required by 12 months of age. Patients with Type 2 or 3 SMA were at risk of losing respiratory function over time, with ventilatory support initiated between the first and fifth decades of life. Swallowing and feeding difficulties, including choking, chewing problems, and aspiration, were reported in patients across the SMA spectrum. Swallowing and feeding difficulties, and a need for non-oral nutritional support, were reported before 1 year of age in Type 1 SMA, and before 10 years of age in Type 2 SMA. Limited data relating to other bulbar functions were collated.
    UNASSIGNED: Natural history data demonstrate that untreated patients with SMA experience respiratory and bulbar function deterioration, with a more rapid decline associated with greater disease severity. This study provides a comprehensive repository of natural history data on bulbar function in SMA, and it highlights that consistent assessment of outcomes in this area is necessary to benefit understanding and approval of new treatments.
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  • 文章类型: Journal Article
    了解接受头颈部辐射的患者的预防性吞咽和三联肌锻炼的障碍和促进因素可能有助于锻炼依从性。该分析审查了所有已发布的运动依从性报告,并根据PRISMA指南进行了严格评估。共确定了137篇潜在论文;20项研究符合纳入标准。最常报道的吞咽和牙关练习的促进者是定期的临床医生联系和在线资源,以加强指导,设定目标,管理辐射毒性。据报道,社会支持和锻炼带来的好处也有所帮助。运动最常见的障碍是辐射毒性,焦虑,感觉被信息淹没了,不理解练习的原因。在为接受头颈部癌症放射治疗的患者设计运动干预措施时,了解促进者和依从性障碍至关重要。
    Understanding the barriers and facilitators for prophylactic swallowing and trismus exercises for patients undergoing radiation to the head and neck may help exercise adherence. The analysis reviews all published reports of exercise adherence with a critical appraisal following PRISMA guidelines. A total of 137 potential papers were identified; 20 studies met the inclusion criteria. The most commonly reported facilitators for swallowing and trismus exercises were regular clinician contact and online resources to reinforce instructions, set goals, and manage radiation toxicities. Social support and perceived benefit from exercises were also reported to be of help. The most common barriers to exercise were radiation toxicities, anxiety, feeling overwhelmed with information, and not understanding the reason for the exercises. Understanding facilitators and barriers to adherence is critical when designing exercise interventions for patients undergoing radiation for head and neck cancer.
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  • 文章类型: Journal Article
    本范围审查旨在确定获取和分析成人和老年人吞咽相关超声图像的方法学程序。纳入标准基于PCC战略(参与者,概念,和上下文),如下:人口(成年人和老年人),概念(超声评估),和上下文(吞咽评估)。审查包括观察,实验性的,描述性,描述性和分析研究,并排除了那些无法完全获得的研究,动物研究,体外研究,给编辑的信,勘误表,研究协议,以及那些使用超声波进行吞咽以外的目的。没有语言和时间限制。两名独立的盲人专业人士从不同的数据库中选择了81篇符合入选标准的文章。评估最多的参数包括舌头形态和运动,舌骨移位,吞咽肌肉区域,和咽部残留检测,如咽壁移动性。他们使用凸形和线性换能器(3MHz至8MHz)定位在下颌,喉,和颈部的外侧区域。受试者就座并被指示食用不同的食物量和稠度。文献图显示,超声是一种有前途的诊断工具,帮助临床医生了解吞咽障碍,因为它在不同的模式和位置提供静态和动态图像。此外,患者接受与吞咽困难相关的变化的实时生物反馈。
    This scoping review aimed to identify methodological procedures for acquiring and analyzing ultrasound images related to swallowing in adults and older adults. The inclusion criteria were based on the PCC strategy (participants, concept, and context), as follows: population (adults and older adults), concept (ultrasound assessment), and context (swallowing assessment). The review included observational, experimental, descriptive, and analytical studies and excluded those that were not available in full, animal studies, in vitro studies, letters to the editor, errata, study protocols, and those that used ultrasound for purposes other than swallowing. There were no language and time restrictions. Two independent blinded professionals selected 81 articles that met the inclusion criteria from different databases. The most evaluated parameters included tongue morphology and movements, hyoid bone displacement, swallowing muscle area, and pharyngeal residue detection, such as pharyngeal wall mobility. They used convex and linear transducers (3 MHz to 8 MHz) positioned in the submental, laryngeal, and lateral regions of the neck. The subjects were seated and instructed to eat different food volumes and consistencies. The literature mapping showed that ultrasound is a promising diagnostic tool, helping clinicians understand swallowing disorders, as it provides static and dynamic images in different modes and positions. Also, patients receive real-time biofeedback of changes related to dysphagia.
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  • 文章类型: Systematic Review
    目的:系统评价旨在提供关于在儿科中使用纤维内窥镜吞咽评估(FEES)的最新技术的概述,特别调查费用的可行性,安全,诊断准确性,和协议。
    方法:在四个电子数据库中搜索了关于儿科人群的原始研究,这些研究使用FEES对吞咽功能进行仪器评估。对纳入研究的参考文献进行了手工搜索。人口数据,内窥镜插入和推注试验的可行性,不良事件,敏感性和特异性,并提取了费用设备和方案。使用JohannaBriggs研究所的清单评估研究的质量。研究的选择,数据提取,质量评价由两名独立研究人员进行。
    结果:纳入81项研究的82份报告。研究的平均总体质量为80%(17-100%)。内窥镜插入的可行性较高(89%-100%),而推注试验的可行性从40%到100%不等。不良事件是过度哭泣(8项研究),烦躁或躁动(4项研究),短暂的氧去饱和(3项研究,1.2-6.7%的患者),鼻出血(3项研究,0.8-3.3%的患者),心率增加(1项研究,1名患者),呕吐(1项研究,1名患者),高张力(1项研究),和唾液分泌过度(1项研究)。无重大并发症报告。使用VFSS作为参考标准,通常发现FEES对抽吸不太敏感(25-94%),但更具体(75-100%),而穿透力则相反(灵敏度76-100%,特异性44-83%)。FES协议高度异构,报告不佳。
    结论:费用是安全的,准确,在疑似吞咽困难的儿科人群中进行检查通常是可行的。然而,目前对于临床实践和研究的最佳FEES方案缺乏共识.
    OBJECTIVE: The systematic review aimed to provide an overview of the state-of-art regarding the use of fiberoptic endoscopic evaluation of swallowing (FEES) in pediatrics, specifically investigating FEES feasibility, safety, diagnostic accuracy, and protocols.
    METHODS: Four electronic databases were searched for original studies on the pediatric population that instrumentally assessed swallowing function using FEES. A hand-search of the references of included studies was performed. Data on the population, feasibility of endoscope insertion and bolus trials, adverse events, sensitivity and specificity, and FEES equipment and protocol were extracted. The quality of the studies was assessed using the checklists of the Johanna Briggs Institute. Selection of the studies, data extraction, and quality appraisal were conducted by two independent researchers.
    RESULTS: Eighty-two reports from 81 studies were included. The mean overall quality of the studies was 80 % (17-100 %). The feasibility of endoscope insertion was high (89%-100 %), while the feasibility of bolus trials varied from 40 % to 100 %. Adverse events were excessive crying (8 studies), irritability or agitation (4 studies), transitory oxygen desaturations (3 studies, 1.2-6.7 % of the patients), epistaxis (3 studies, 0.8-3.3 % of the patients), increased heart rate (1 study, 1 patient), vomiting (1 study, 1 patient), hypertonia (1 study), and hypersalivation (1 study). No major complications were reported. Using VFSS as the reference standard, FEES was generally found to be less sensitive (25-94 %) but more specific (75-100 %) for aspiration, whereas the reverse was true for penetration (sensitivity 76-100 %, specificity 44-83 %). FEES protocols were highly heterogeneous with poor reporting.
    CONCLUSIONS: FEES is a safe, accurate, and generally feasible examination in the pediatric population with suspected dysphagia. However, a consensus on the best FEES protocol for clinical practice and research is currently lacking.
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