UNASSIGNED: Isolated osteomyelitis of the cuboid is a rare entity with very few case reports worldwide. A variety of treatment methods are described for these lesions, both single-stage and two staged and ranges from simple curettage to bone grafting and arthrodesis.
UNASSIGNED: We present a series of two cases of chronic osteomyelitis in young adults due to puncture wound over the lateral foot. Both patients presented with purulent discharge from sinus over lateral foot. There was no involvement of adjoining bones in them. Culture yielded Staphylococcus aureus and Pseudomonas aeruginosa. Both patients were treated with adequate curetting, saucerization with cancellous bone grafting in one of the cases. Both wounds healed uneventfully with good ankle and hindfoot function.
UNASSIGNED: The cuboid is a rare site of chronic osteomyelitis due to punture wounds with foreign bodies, especially in rural population. With meticulous curettage and bone grafting, the infection can be eradicated reliably and usually with good residual function.

Cuboid dislocations are rare midfoot injuries that usually occur in the setting of high-energy trauma. Diagnosis can be challenging and optimal treatment remains unknown. This case report and review aims to summarize the recent literature on this topic.

BACKGROUND: Brodie\'s abscess of cuboid bone is one of the rarest diagnosis in children which most often is hematogenous in origin. Although Streptococcus pyogenes has been uncommonly implicated as causative organism in other bones, it is not yet reported in the cuboid.
METHODS: We report the case of 14-year-old boy who presented with a lytic lesion in the cuboid bone. It was preceded by a penetrating injury with a small iron nail. He was treated with simple curettage without the addition of bone graft. Frank pus present in the cavity in the cuboid bone grew S. pyogenes on bacterial culture. Symptoms resolved after 6 weeks of antibiotics, however, complete radiological healing was obtained after 9 months.
CONCLUSIONS: Although very rare, S. pyogenes associated Brodie\'s abscess should strongly be suspected in a posttraumatic lytic lesion in the cuboid bone and bone grafting is not always required for bone healing even in presence of large pus-filled cavity.

BACKGROUND: Cuboid syndrome is thought to be a common source of lateral midfoot pain in athletes.
METHODS: A Medline search was performed via PubMed (through June 2010) using the search terms cuboid, syndrome, subluxed, locked, fault, dropped, peroneal, lateral, plantar, and neuritis with the Boolean term AND in all possible combinations. Retrieved articles were hand searched for additional relevant references.
RESULTS: Cuboid syndrome is thought to arise from subtle disruption of the arthrokinematics or structural congruity of the calcaneocuboid joint, although the precise pathomechanic mechanism has not been elucidated. Fibroadipose synovial folds (or labra) within the calcaneocuboid joint may play a role in the cause of cuboid syndrome, but this is highly speculative. The symptoms of cuboid syndrome resemble those of a ligament sprain. Currently, there are no definitive diagnostic tests for this condition. Case reports suggest that cuboid syndrome often responds favorably to manipulation and/or external support.
CONCLUSIONS: Evidence-based guidelines regarding cuboid syndrome are lacking. Consequently, the diagnosis of cuboid syndrome is often based on a constellation of signs and symptoms and a high index of suspicion. Unless contraindicated, manipulation of the cuboid should be considered as an initial treatment.