■2019年冠状病毒病(COVID-19)扰乱了标准的卫生政策和常规医疗保健,因此,许多临床疾病的管理和治疗途径发生了前所未有的变化。大流行的负面影响使全身性疾病更加复杂并加速了死亡率。在过去的两年里,临床医生主要关注COVID-19患者;然而,非COVID-19危重患者需要从多个角度加以解决。这项研究调查了与COVID-19波同时入院的非COVID-19重症监护患者的人口统计学和临床特征。这项研究的目的是确定危重非COVID-19患者死亡的危险因素。
■在2021年1月1日至2021年7月14日期间,所有入住重症监护病房(ICU)的连续病例均纳入研究。所有数据,包括年龄,性别,录取特点,患者依赖性,预先存在的全身性疾病,疾病的严重程度(急性生理学和慢性健康评估-APACHE-II),ICU预测死亡率,入院时或ICU住院期间维持生命的医疗程序,逗留时间,以及入住ICU的时间,是从医院的电子数据库中获得的。对所有患者进行Charlson合并症指数(CCI)评估。
■在研究期间共筛选了192名患者。非手术患者的死亡率显着增加,以前依赖的患者,需要机械通气的患者,连续性肾脏替代疗法,以及需要输注血管活性药物的患者。预先存在的疾病数量和入院时间对死亡率没有影响。非幸存者的平均CCI明显较高,但不是APACHEII死亡率的强预测因子。
■在这项回顾性研究中,多变量分析证实为危重的非COVID-19患者死亡的预测因素,非幸存者的疾病严重程度和需要输注血管活性药物的比例显著升高.
UNASSIGNED: Coronavirus disease 2019 (COVID-19) disrupted standard health policies and routine medical care, and thus, the management and treatment pathways of many clinical conditions have changed as never before. The negative impact of the pandemic rendered the systemic disease more complicated and accelerated mortality. For the last two years, clinicians have primarily focused on COVID-19 patients; however, the non-COVID-19 critically ill patients needed to be addressed from multiple perspectives. This
study investigated the demographic and clinical characteristics of non-COVID-19 critical care patients admitted concurrently with a COVID-19 wave. The objective of this
study was to identify the risk factors for mortality in critically ill non-COVID-19 patients.
UNASSIGNED: All consecutive cases admitted to the intensive care unit (ICU) were included in the
study between January 1, 2021 and July 14, 2021. All data, including age, gender, admission characteristics, patient dependency, pre-existing systemic diseases, the severity of illness (Acute Physiology and Chronic Health Evaluation -APACHE-II), predicted death rate in ICU, life-sustaining medical procedures on admission or during ICU stay, length of stay, and admission time to the ICU, were obtained from the hospital\'s electronic database. The Charlson Comorbidity Index (CCI) was assessed for all patients.
UNASSIGNED: A total of 192 patients were screened during the
study period. Mortality was significantly increased in non-surgical patients, previously dependent patients, patients requiring mechanical ventilation, continuous renal replacement therapy, and patients requiring the infusion of vasoactive medications. The number of pre-existing diseases and the admission time had no impact on mortality. The mean CCI was significantly higher in non-survivors but was not a strong predictor of mortality as APACHE II.
UNASSIGNED: In this retrospective
study, the severity of illness and the need for vasoactive agent infusion were significantly higher in non-survivors confirmed by multivariate analysis as predictive factors for mortality in critical non-COVID-19 patients.