本研究的目的是回顾所有实施患者报告结果测量(PROMs)以评估角膜移植中的生活质量(QoL)的文章,并讨论PROMs的质量评估。进行了广泛的文献综述,以确定使用PROMs评估角膜移植中QoL的所有研究。非原创或评论文章,关于其他主题领域的文章和关于无PROM数据/结果的成本效益/实用性的文章被排除.每个PROM都根据以下标准进行评估:内容开发(项目识别和项目选择),心理测量属性,有效性,可靠性,和响应性。确定了425篇文章,其中35篇文章被纳入最终审查。角膜移植中的PROM用于(a)评估手术后的QoL,(b)比较不同手术技术之间的QoL评分,(c)确定QoL与视力等客观指标之间的关系,视野和立体感。共有17个PROM用于评估角膜移植中的QoL。虽然这项搜索没有产生任何专门用于评估角膜移植的PROM,发现大多数研究采用了国家眼科研究所视觉功能问卷25(NEIVFQ25)。视觉功能指数14(VF14)在当前质量评估标准中的表现优于其他PROM,然而,NEIVFQ25和VF14PROM不是专门为角膜移植开发的,因此使用这些PROM进行的QoL评估可能不完整.随着UT-DSAEK和FT-DSAEK等各种形式的板层移植手术技术的改进,视觉效果更好,提高移植物存活率,减少并发症,角膜移植特异性胎膜早破在临床中很有用,可以从患者角度比较不同手术技术的结局.
The aim of this study was to
review all the articles that have implemented patient-reported outcome measures (PROMs) to evaluate the quality of life (QoL) in corneal transplantation and discuss quality assessments of the PROMs. An extensive literature
review was undertaken to identify all the studies that used PROMs to assess the QoL in
corneal transplantation. Non-original or
review articles, articles on other subject area and articles on cost-effectiveness/utility without PROM data/results were excluded. Each PROM was assessed against the following criteria: content development (item identification and item selection), psychometric properties, validity, reliability, and responsiveness. 425 articles were identified of which 35 articles were included in the final
review. PROMs in corneal transplantation were used to (a) evaluate the QoL after surgery, (b) compare the QoL scores between different surgical techniques and (c) determine the relationship between QoL and objective measures such as visual acuity, visual field and stereoacuity. A total of 17 PROMs were used to assess QoL in
corneal transplantation. Whilst this search did not produce any PROMs that were specifically designed to assess corneal transplantation, most studies were found to have employed the National Eye Institute Visual Function Questionnaire 25 (NEI VFQ 25). The Visual Function Index 14 (VF 14) performed better in the present quality assessment criteria compared to other PROMs, however, the NEI VFQ 25 and the VF 14 PROMs were not specifically developed for corneal transplantation and therefore the QoL assessment made using these PROMs may be incomplete. As improvements in various forms of lamellar transplantation surgery techniques such as UT-DSAEK and FT-DSAEK have resulted in better visual outcomes, improved graft survival and reduced complications, a corneal transplantation specific PROM will be useful in clinical settings to compare the outcomes of different surgical techniques from the patient perspective.