是全球死亡和残疾的主要原因之一,癌症代表了科学界正在进行的跨学科挑战。由于目前使用的治疗方法可能在效率和不良反应方面都面临限制,持续的研究旨在克服现有挑战,寻找更安全的具体替代品。特别是,越来越多的兴趣集中在将纳米技术整合到癌症管理中,并随后开发用于癌症应用的各种肿瘤靶向纳米颗粒.在这方面,本文简要介绍了临床实践中最常用的癌症治疗方法,为最近的研究结果建立了参考框架,进一步关注该领域的新发展。更具体地说,这篇综述详细阐述了有关各种纳米材料的最新研究(即,碳基,以金属为基础,脂质体,立方体,基于脂质的,聚合物基,胶束,基于病毒的,外泌体,和细胞膜涂层纳米材料),在不同的癌症应用中显示出有希望的潜力。
Being one of the leading causes of death and disability worldwide, cancer represents an ongoing interdisciplinary challenge for the scientific community. As currently used treatments may face limitations in terms of both efficiency and adverse effects, continuous research has been directed towards overcoming existing challenges and finding safer specific alternatives. In particular, increasing interest has been gathered around integrating nanotechnology in cancer management and subsequentially developing various tumor-targeting nanoparticles for cancer applications. In this respect, the present paper briefly describes the most used cancer treatments in clinical practice to set a reference framework for recent research findings, further focusing on the novel developments in the field. More specifically, this
review elaborates on the top recent studies concerning various nanomaterials (i.e., carbon-based, metal-based, liposomes, cubosomes, lipid-based, polymer-based, micelles, virus-based, exosomes, and cell membrane-coated nanomaterials) that show promising potential in different cancer applications.