Conservative therapy

保守治疗
  • 文章类型: Case Reports
    背景:巨大颅内动脉瘤(GIA)的患者破裂的风险很高,发病率,甚至在手术或血管内治疗后的死亡率。我们描述了一例自发闭塞的GIA,继发于GIA的逐渐生长,持续进展的动脉瘤血栓形成,完整的动脉瘤钙化和完全闭塞的父动脉-右颈内动脉(RICA)。
    方法:一名72岁女性患者入院时主诉右眼突然疼痛。她被诊断为GIA[30mm(轴向)×38mm(冠状)×28mm(矢状)],其中包含通过磁共振成像(MRI)诊断的RICA海绵窦段中的动脉瘤血栓,增强MRI,和14年前的磁共振血管造影。稍后,随着海绵状颈动脉GIA的缓慢生长,动脉瘤血栓形成持续进展,RICA的自发闭塞,完整的动脉瘤钙化,GIA逐渐闭塞。她没有蛛网膜下腔出血的病史,但错过了早期血管内治疗的机会。因此,她的右颅神经II受伤留下了严重的永久性后遗症,III,IV,V1/V2和VI。
    结论:海绵状颈动脉GIAs破裂的风险相对较低,并且可能由于海绵状颈动脉GIAs的质量效应和极其罕见的动脉瘤钙化引起的母动脉颈内动脉(ICA)的淤滞流和自发闭塞而进一步降低。然而,如今,建议对海绵状颈动脉GIAs进行早期血管内治疗,以防止周围颅内神经损伤和ICA闭塞,主要由海绵样颈动脉GIAs的质量效应引起。
    BACKGROUND: Patients with giant intracranial aneurysms (GIAs) are at a high risk of rupture, morbidity, and mortality even after surgical or endovascular treatment. We described a case of a spontaneously occluded GIA secondary to gradual growth of the GIA, continuously progressed aneurysmal thrombosis, complete aneurysmal calcification and complete occlusion of the parent artery-the right internal carotid artery (RICA).
    METHODS: A 72-year-old female patient complained of sudden pain in her right eye upon admission to our hospital. She had been diagnosed with a GIA [30 mm (axial) × 38 mm (coronal) × 28 mm (sagittal)] containing an aneurysmal thrombus located in the cavernous sinus segment of RICA diagnosed by magnetic resonance imaging (MRI), enhanced MRI, and magnetic resonance angiography more than 14 years ago. Later, with slow growth of the cavernous carotid GIA, aneurysmal thrombosis progressed continuously, spontaneous occlusion of the RICA, complete aneurysmal calcification, and occlusion of the GIA occurred gradually. She had no history of subarachnoid hemorrhage but missed the chance for endovascular therapy at an early stage. As a result, she was left with severe permanent sequelae from the injuries to the right cranial nerves II, III, IV, V1/V2, and VI.
    CONCLUSIONS: The risk of rupture of the cavernous carotid GIAs was relatively low and possibly further be reduced by the stasis flow and spontaneous occlusion of the parent artery internal carotid artery (ICA) induced by the mass effect of the cavernous carotid GIAs and the extremely rare aneurysmal calcification. However, nowadays, it is advisable to recommend early endovascular treatment for the cavernous carotid GIAs to prevent injuries to the surrounding intracranial nerves and occlusion of the ICA, mainly caused by the mass effect of the cavernous carotid GIAs.
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  • 文章类型: Case Reports
    一名76岁的妇女因高烧和膀胱刺激症状而被转诊到我们部门。计算机断层扫描显示膀胱左前壁上存在异质肿块,边界不清。病变包含线性高密度阴影。我们最初怀疑是恶性肿瘤,例如脐管癌或软组织肉瘤。然而,在回顾以前的计算机断层扫描后,证实线性高密度阴影已从肠道迁移到膀胱。考虑到异物导致脓肿形成的可能性,我们决定进行经尿道活检.病理分析结果显示脓肿形成。患者被诊断为因意外摄入鱼骨而引起的膀胱周围脓肿。在服用抗生素后,病变明显缩小。尽管很难区分膀胱周围脓肿和恶性疾病,通过基于影像学研究的适当诊断,可以避免侵入性治疗。
    A 76-year-old woman was referred to our department because of high fever and bladder irritative symptoms. Computed tomography revealed the presence of a heterogeneous mass with indistinct borders on the left anterior wall of the bladder. The lesion contained a linear hyperdense shadow. We initially suspected malignancy, such as urachal carcinoma or soft-tissue sarcoma. However, upon review of previous computed tomography scans, it was confirmed that the linear hyperdense shadow had migrated from the intestinal tract to the bladder. Considering the possibility of abscess formation caused by a foreign body, we decided to perform a transurethral biopsy. The results of the pathological analysis showed abscess formation. The patient was diagnosed with perivesical abscess caused by accidental ingestion of a fish bone. Following the administration of antibiotics, the lesion markedly shrank. Although it is difficult to distinguish perivesical abscess from malignant disease, invasive treatment can be avoided by appropriate diagnosis based on imaging studies.
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  • 文章类型: Case Reports
    寰椎(C1)和颅底枕骨融合在一起,一种罕见的先天性异常.因为它会导致颈椎不稳定,神经撞击,和相关症状,包括僵硬,疼痛,和神经损伤,它提出了一个具有挑战性的治疗问题。我们描述了一个女病人的情况,27岁,颈部不适逐渐恶化,刚度,以及在就诊前六年宫颈活动受限。尽管经过保守治疗,她的症状随着时间的推移而恶化,所以更多的测试是必要的。Atlascipitalization,C7和D1椎骨的先天性融合,通过影像学检查确定了其他相关的颈椎病理。在这个案例研究中突出了寰枕和相关的颈椎病理的复杂性,以及解决这些问题所需的诊断困难和跨学科治疗策略。为了提高颈椎的活动范围(ROM),减轻不适,并改善功能结果,患者接受了彻底的肌肉骨骼检查,并接受了定制的理疗干预。
    The atlas (C1) and occipital bone at the base of the skull fuse together in atlas occipitalization, an uncommon congenital abnormality. Because it can result in cervical spine instability, nerve impingement, and related symptoms including stiffness, pain, and neurological impairments, it poses a challenging therapeutic problem. We describe the case of a female patient, 27 years old, who had gradually deteriorating neck discomfort, stiffness, and limited cervical mobility for six years prior to presentation. Her symptoms worsened over time despite conservative treatment, so more testing was necessary. Atlas occipitalization, congenital fusion at the C7 and D1 vertebrae, and other related cervical spine pathologies were identified by imaging examinations. The intricacies of atlas occipitalization and related cervical spine pathologies are highlighted in this case study, along with the diagnostic difficulties and interdisciplinary therapeutic strategy needed to address them. To improve cervical range of motion (ROM), lessen discomfort, and improve functional results, the patient underwent a thorough musculoskeletal examination and was given a customized physiotherapeutic intervention.
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  • 文章类型: Case Reports
    线粒体肌病患者,脑病,乳酸性酸中毒,和中风样发作(MELAS),线粒体疾病,发展各种类型的器官衰竭,包括肠道假性梗阻(IPO)。我们治疗了一名首次公开募股的患者,该患者通过全胃肠外营养得到改善。一名有两年糖尿病病史的20岁女性正在服用西格列汀,但她的血红蛋白A1c(HbA1c)水平开始升高。服用二甲双胍后,她遭受了类似中风的发作,并被诊断出患有MELAS。持续厌食症后,她出现了IPO的症状,如呕吐和胃肠扩张。经过大约10天的全胃肠外营养,肠蠕动改善,肠蠕动恢复。她能够恢复正常饮食,使用甘精胰岛素的血糖控制使她在六个月以上没有胃肠道症状的情况下恢复了日常生活。全胃肠外营养可能对首次公开募股的MELAS有效,良好的血糖控制可以防止对肠促胰岛素相关药物的需要,从而降低了反复IPO的可能性。
    Patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), a mitochondrial disease, develop various types of organ failure, including intestinal pseudo-obstruction (IPO). We treated a patient with IPO that improved with total parenteral nutrition.  A 20-year-old woman with a two-year history of diabetes mellitus was taking sitagliptin but her hemoglobin A1c (HbA1c) levels began increasing. After receiving metformin, she suffered a stroke-like attack and was diagnosed with MELAS. After persistent anorexia, she presented with symptoms of IPO, such as vomiting and gastrointestinal dilatation. After about 10 days of total parenteral nutrition, intestinal peristalsis improved and bowel movements resumed. She was able to resume her normal diet, and glycemic control with insulin glargine has allowed her to return to her daily life without gastrointestinal symptoms for over six months. Total parenteral nutrition may be effective for MELAS with IPO, and good glycemic control can prevent the need for incretin-related drugs, thus reducing the likelihood of recurrent IPO.
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  • 文章类型: Case Reports
    颌骨跛行是巨细胞动脉炎(GCA)的常见症状,尽管动脉粥样硬化血栓性颈外动脉(ECA)闭塞也已知会导致颌骨跛行。患者是一名75岁的男性,在咀嚼固体食物时出现严重的右下颌疼痛。磁共振(MR)血管造影显示右侧ECA闭塞。根据实验室检查和对比增强计算机断层扫描(CT)血管造影,动脉粥样硬化血栓形成,不是GCA,被怀疑是导致颌骨跛行的原因.西洛他唑保守治疗后,疼痛在两个月内逐渐减轻,四个月后的MR血管造影显示狭窄的右侧ECA有血流。症状在六个月内完全消失。根据之前的一份报告,我们预计,由于抵押品供应的发展,颌骨跛行将会得到改善;然而,在这种情况下,自发性ECA再通导致症状改善。
    Jaw claudication is a common symptom of giant cell arteritis (GCA), although atherothrombotic external carotid artery (ECA) occlusion is also known to cause jaw claudication. The patient was a 75-year-old male who experienced severe right jaw pain while chewing solid food. Magnetic resonance (MR) angiography showed right ECA occlusion. Based on laboratory tests and contrast-enhanced computed tomography (CT) angiography, atherothrombosis, not GCA, was suspected to be the cause of jaw claudication. Following conservative therapy with cilostazol, the pain was gradually alleviated in two months, and subsequent MR angiography after four months showed blood flow in the stenosed right ECA. The symptom completely disappeared in six months. Based on a previous report, we expected that jaw claudication will be ameliorated due to the development of collateral supply; however, spontaneous ECA recanalization caused improvement of symptoms in this case.
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  • 文章类型: Case Reports
    食管裂孔疝引起的胃穿孔是急性腹痛的罕见原因,通常需要手术干预。在某些情况下,对这种情况的保守管理是一种有效的选择,尽管这方面的报道较少。在这里,我们报道了一例由复发性食管裂孔疝引起的胃穿孔的独特病例,该病例经保守治疗成功。
    方法:一名74岁男子在腹腔镜食管旁疝修补术后第3天出现高烧和炎症反应升高。计算机断层扫描证实食管裂孔疝复发,胃底脱垂到纵隔和胃壁的外科肺气肿。随后是纵隔内的胃穿孔。患者使用肠梗阻管通过穿孔部位进行治疗。
    在类似情况下,如果临床症状轻微,没有严重感染的迹象,穿孔留在纵隔,可以适当引流,保守治疗被认为是一种选择.
    结论:在有利条件下,保守治疗可作为复发性食管裂孔疝患者胃穿孔的一种选择,这是严重的潜在术后并发症。
    UNASSIGNED: Gastric perforation due to a hiatal hernia is a rare cause of acute abdominal pain that often requires surgical intervention. Conservative management for this condition is an effective option in certain cases, although fewer reports of this exist. Herein, we report a unique case of gastric perforation caused by a recurrent hiatal hernia that was successfully treated with conservative management.
    METHODS: A 74-year-old man developed a high fever and an elevated inflammatory response on the third day after a laparoscopic paraesophageal hernia repair using a mesh. Computed tomography confirmed the recurrence of the hiatal hernia, with gastric fundal prolapse into the mediastinum and surgical emphysema in the gastric wall. This was followed by a gastric perforation within the mediastinum. The patient was treated using an ileus tube through the perforation site.
    UNASSIGNED: In similar cases, if the clinical symptoms are mild, there are no signs of serious infection, and the perforation remains in the mediastinum and can be appropriately drained, conservative treatment is considered an option.
    CONCLUSIONS: Under favorable conditions, conservative management can be an option for gastric perforation in patients with recurrent hiatal hernias, which is a serious potential postoperative complication.
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  • 文章类型: Case Reports
    胃肠道(GIT)症状越来越多地报道为2019年冠状病毒病(COVID-19)的表现症状。这些症状从腹泻到严重结肠炎或出血不等。本文报道了一名先前健康的52岁女性中,由于活跃的COVID-19继发的GIT参与,导致罕见的泛结肠炎病例。通过腹部CT扫描证实了诊断,患者住院并保守治疗,住院三天后出院回家。她在门诊外科诊所接受了两周的随访,没有更多的胃肠道症状和正常的体检。在COVID-19的背景下仔细考虑胃肠道症状并及时诊断将有助于早期识别和管理,并避免任何险恶的并发症。
    Gastrointestinal tract (GIT) symptoms are increasingly reported as the presenting symptoms of coronavirus disease 2019 (COVID-19). These symptoms vary from diarrhea to severe colitis or bleeding. This paper reports a rare case of pancolitis as a consequence of GIT involvement secondary to active COVID-19 in a previously healthy 52-year-old lady. The diagnosis was confirmed by a CT scan of the abdomen and the patient was hospitalized and treated conservatively and discharged home after three days of hospital admission. She was followed up in the outpatient surgical clinic in two weeks with no more gastrointestinal symptoms and a normal physical examination. Careful consideration of gastrointestinal symptoms in the context of COVID-19 and a prompt diagnosis will facilitate early recognition and management and avoid any sinister complications.
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  • 文章类型: Case Reports
    左心室(LV)假性动脉瘤是急性心肌梗死(AMI)后的罕见疾病。由于假性动脉瘤破裂的倾向很高,因此建议通过手术切除或闭合假性动脉瘤,而手术也具有很高的风险。对于小的假性动脉瘤或手术风险高的患者,保守治疗是可以接受的。然而,风险评估和指征把握不明确。该病例报道了AMI诱发的心肌游离壁破裂(MFWR)后形成的急性囊肿样LV假性动脉瘤,患者通过非手术治疗自发闭合和收缩左心室假性动脉瘤而康复。根据超声心动图的观察,我们提出,由于LV收缩引起的LV和假性动脉瘤之间的裂缝的间歇性闭合和血流的中断减轻了假性动脉瘤的应力变化。狭窄的裂缝,小的假性动脉瘤,间歇性中断的血流有利于裂隙愈合和假性动脉瘤的稳定,这可能表明该患者的预后。β受体阻滞剂等降低假性动脉瘤压力的药物也降低了假性动脉瘤破裂的风险。据我们所知,这是首例报道LV假性动脉瘤自发闭合的病例.裂隙和假性动脉瘤的大小,以及相应的血液动力学状态,可能对评估假性动脉瘤的风险和预后有价值。优化的医疗管理也有助于假性动脉瘤的稳定。
    Left ventricle (LV) pseudoaneurysm is a rare disorder post-acute myocardial infarction (AMI). Resection or closure of the pseudoaneurysm by surgery is recommended due to the high propensity of pseudoaneurysm rupture while surgery has also high risks. Conservative therapy could be acceptable in small pseudoaneurysms or patients with high surgical risks. Nevertheless, the risk evaluation and grasp of indication are not clear. This case reported an acute cyst-like LV pseudoaneurysm formation post-AMI-induced myocardial free wall rupture (MFWR), and the patient recovered with spontaneous closure of the fissure and shrinkage of the LV pseudoaneurysm through non-surgical therapy. Based on the observations in the echocardiogram, we proposed that intermittent closing of the fissure and interruption of the blood flow between the LV and the pseudoaneurysm due to LV contraction alleviated stress change on the pseudoaneurysm. The narrow fissure, small pseudoaneurysm, and intermittently interrupted blood flow that benefit fissure healing and pseudoaneurysm stabilization could indicate the prognosis of this patient. Drugs like β-blocker that decreased the stress on the pseudoaneurysm also led to the risk reduction of pseudoaneurysm rupture. To our knowledge, this is the first case that reports a spontaneous closure of LV pseudoaneurysm. The size of the fissure and the pseudoaneurysm, as well as the corresponding hemodynamic state, could be valuable to evaluate the risk and prognosis of the pseudoaneurysm. Optimized medical management was also helpful to pseudoaneurysm stabilization.
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  • 文章类型: Case Reports
    Takotsubo心肌病(TC)是一种病因不明的罕见疾病,其特征是左心室壁运动异常。我们报告了一名64岁的女性,在输尿管支架置入术后6小时出现心脏骤停,没有心脏病史.值得注意的是,她术前有尿路感染。TC在左心室图中被诊断为特征性心尖部球囊扩张。在保守治疗和控制感染后1天内血流动力学和心功能迅速恢复。当患者在输尿管支架置入术后出现心功能下降时,应考虑TC。尤其是潜在并发感染的患者。使用PubMed对过去十年中记录与泌尿外科手术有关的TC病例的文献进行了回顾。结果总结在表中。
    Takotsubo cardiomyopathy (TC) is a rare disease with unclear etiology that is characterized by wall motion abnormalities of the left ventricle. We report a 64-year-old woman who presented with cardiac arrest 6 hours after ureteral stenting, with no history of heart disease. Notably, she had a urinary tract infection preoperatively. TC was diagnosed with characteristic apical ballooning on the left ventriculogram. The hemodynamics and cardiac function recovered quickly within 1 day after conservative treatment and controlling the infection. TC should be considered when a patient presents with decreased cardiac function after ureteral stenting, especially in patients with potential concurrent infection. A review of the literature documenting cases of TC related to urological surgery in the past decade was conducted using PubMed. The results were summarized in a table.
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  • 文章类型: Case Reports
    自发性孤立性肠系膜上动脉夹层(SISMAD)是一种罕见且可能致命的原因,诊断表现为急腹症;然而,因为它的稀有性,SISMAD的致病因素尚不清楚,尚无明确的病因。此外,缺乏循证治疗指南.
    Spontaneous isolated superior mesenteric artery dissection (SISMAD) is a rare and potentially fatal cause diagnosis presenting with acute abdominal; however, because of its rarity, the pathogenic factors of SISMAD remain unknown and no clear cause has been found. Moreover, there is a lack of evidence-based treatment guidelines.
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