在先天性眼球震颤(CN)患者中,前庭功能的研究由于许多因素而变得复杂,这些因素与通过热量测试和视频头脉冲测试(vHIT)来测量前庭眼反射(VOR)有关,迄今为止,尚无此类研究成功地使用vHIT来评估这些患者的前庭功能。我们介绍了一个CN和眩晕的病例,其中使用vHIT系统评估了周围前庭功能,包括头部脉冲测试和抑制头部脉冲协议。我们证明有可能(a)识别横向VOR变化,例如与双侧前庭病变产生的异常相似,尽管不一定与相同的机制相关;(b)确定垂直半规管(SCC)的外周VOR病变;和(c)在CN患者的随访期间记录这些外周病变的补偿和恢复。vHIT是一个有用的工具,应用于研究CN和眩晕患者的前庭功能,这可能构成该技术的新临床应用。
In patients with congenital nystagmus (CN), the study of vestibular function is complicated by many factors related to the measurement of the vestibulo-ocular reflex (VOR) by means of caloric testing and the video head impulse test (vHIT), and to date no such studies have successfully employed the vHIT to evaluate vestibular function in these patients. We present a
case with CN and vertigo in which peripheral vestibular function was evaluated using the vHIT system, including head impulse testing and the suppression head impulse protocol. We show that it is possible (a) to identify lateral VOR changes such as abnormalities resembling those produced by bilateral vestibular lesions, though not necessarily related to the same mechanism; (b) to identify peripheral VOR lesions of the vertical semicircular canals (SCC); and (c) to document compensation and recovery subsequent to these peripheral lesions during follow-up of patients with CN. vHIT is a useful tool that should be used to study vestibular function in patients with CN and vertigo, which could constitute a new clinical application of this technique.