UNASSIGNED:分析先天性鼻泪管阻塞(CNLDO)儿童的微生物学谱和抗生素敏感性模式。
UNASSIGNED:这项前瞻性比较研究纳入了123例年龄在0-16岁的儿童,诊断为CNLDO,并接受了泪道外科手术。计划进行鼻泪管未闭眼内手术的年龄匹配组的62名儿童被视为对照组。CNLDO组对泪囊进行压力反流后的结膜拭子和对照组的结膜拭子被送去进行微生物学分析。通过KirbyBauer圆盘扩散法对常用抗生素进行了抗生素敏感性测试。
未经证实:在CNLDO组收集的134个样本中,111(82.8%)样品为培养阳性。分离出165种细菌,其中革兰氏阳性菌139例(84.24%),26例(15.75%的分离株)为革兰氏阴性。在2.23%的病例中获得了真菌分离株。最常见的革兰氏阳性分离株是表皮葡萄球菌(S.表皮)(n=51,占总分离株的30.9%),最常见的革兰氏阴性分离株是流感嗜血杆菌(n=9,占总分离株的5.5%)。革兰阳性菌株对庆大霉素和万古霉素的敏感性最高(各95.5%),革兰氏阴性菌株对阿米卡星(92.3%)。革兰氏阳性和革兰氏阴性分离株均对加替沙星敏感(各80%)。革兰氏阳性的探测结果相似(成功,84.6%)和革兰氏阴性(成功,84.0%)生物。
未经证实:在CNLDO患儿中,革兰氏阳性分离株占主导地位,表皮葡萄球菌是最常见的。微生物概况对探测结果没有任何影响。
UNASSIGNED: To analyze the microbiological spectrum and antibiotic sensitivity patterns in children with congenital nasolacrimal duct obstruction (CNLDO).
UNASSIGNED: One hundred thirty-four eyes of 123 children in the age group of 0-16 years with a diagnosis of CNLDO who underwent lacrimal surgical procedures were included in this prospective comparative study. Sixty-two children in the age-matched group planned for intraocular surgery with patent nasolacrimal duct were deemed controls. The conjunctival swab after performing Regurgitation on Pressure over the Lacrimal Sac in the CNLDO group and the conjunctival swab in controls were sent for microbiological analysis. Antibiotic susceptibility testing was done for commonly employed antibiotics by the Kirby Bauer disk diffusion method.
UNASSIGNED: Of 134 samples collected in the CNLDO group, 111 (82.8%) samples were culture positive. There were 165 bacteria isolated, among which 139 (84.24% of isolates) were Gram-positive bacteria, and 26 (15.75% of isolates) were Gram-negative. Fungal isolates were obtained in 2.23% of cases. The most common Gram-positive isolate was Staphylococcus epidermidis (S. epidermidis) (n = 51, 30.9% of total isolates), and the most common Gram-negative isolate was Haemophilus influenza species (n = 9, 5.5% of total isolates). Gram-positive isolates were sensitive mostly to gentamicin and vancomycin (95.5% each), and Gram-negative isolates to amikacin (92.3%). Both Gram-positive and Gram-negative isolates were susceptible to gatifloxacin (80% each). Probing outcomes were similar among Gram-positive (success, 84.6%) and Gram-negative (success, 84.0%) organisms.
UNASSIGNED: There was a predominance of Gram-positive isolates in children with CNLDO with S. epidermidis being the most common. The microbiological profile did not have any effect on the outcomes of probing.