目的:描述印度多层眼科医院网络患者的葡萄膜缺损的人口统计学和临床特征。
方法:以医院为基础的横断面研究。
方法:这个横截面,基于医院的研究包括2010年8月至2021年5月期间出现的2,817,766名新患者.包括至少1只眼睛的临床诊断为葡萄膜缺损的患者。使用电子病历系统收集数据。
结果:总体而言,9557例患者(0.34%)被诊断为葡萄膜缺损。超过一半的患者是男性(51.82%),并且受到双侧影响(50.37%)。演讲中最常见的年龄组是生命第二个十年的个体,包括2198名患者(23%)。社会经济地位较低的患者(0.53%)和农村地区(0.39%)的总体患病率较高。8049例患者中最常见的类型是视网膜脉络膜缺损(84.22%),其次是虹膜缺损2129例(22.28%)。视网膜脉络膜缺损的最常见的IdaMann分类是7049只眼的4型(57.23%),其次是2型3685眼(29.92%)。在14371只眼睛中,5696眼(39.64%)有视力障碍的失明(>20/400),其次是轻度或无视力障碍(<20/70)的2875眼(20.01%)。在需要手术/激光介入的2228只眼睛(15.5%)中,951只眼(6.62%)进行了白内障手术,玻璃体视网膜手术661眼(4.6%),其次是激光光凝357眼(2.48%)。
结论:葡萄膜缺损在男性个体中更常见,在研究人群中主要为双侧。它更常见于来自较低社会经济阶层和农村背景的患者。最常见的类型是视网膜脉络膜缺损,超过三分之一的眼睛受到失明的影响。
OBJECTIVE: To describe the demographics and clinical profile of uveal coloboma in patients presenting to a multi-tier ophthalmology hospital network in India.
METHODS: Cross-sectional hospital-based
study.
METHODS: This cross-sectional, hospital-based
study included 2,817,766 new patients presenting between August 2010 and May 2021. Patients with a clinical diagnosis of uveal
coloboma in at least 1 eye were included as cases. Data were collected using an electronic medical record system.
RESULTS: Overall, 9557 patients (0.34%) were diagnosed with uveal
coloboma. Just over half of the patients were male (51.82%) and were affected bilaterally (50.37%). The most common age group at presentation was individuals in the second decade of life, comprising 2198 patients (23%). The overall prevalence was higher in patients of lower socio-economic status (0.53%) and from rural areas (0.39%). The most common type was retino-choroidal
coloboma in 8049 patients (84.22%), followed by iris
coloboma in 2129 patients (22.28%). The most common Ida Mann classification in the eyes with retino-choroidal coloboma was type 4 in 7049 eyes (57.23%), followed by type 2 in 3685 eyes (29.92%). Of the 14,371 eyes, 5696 eyes (39.64%) had a visual impairment of blindness (>20/400), followed by mild or no visual impairment (<20/70) in 2875 eyes (20.01%). In the 2228 eyes (15.5%) that required a surgical/ laser intervention, cataract surgery was performed in 951 eyes (6.62%), vitreo-retinal surgery in 661 eyes (4.6%), followed by laser photocoagulation in 357 eyes (2.48%).
CONCLUSIONS: Uveal coloboma is more common in male individuals and is predominantly bilateral in the population studied. It is more commonly found in patients from lower socio-economic strata and from a rural background. The most common type is retino-choroidal coloboma, and more than one-third of the eyes are affected by blindness.