Choroidal Effusions

脉络膜积液
  • 文章类型: Journal Article
    目的:评估重复玻璃体内甲氨蝶呤(IMTX)作为平坦部玻璃体切除术(PPV)的辅助手段在治疗脉络膜脱离(RRDCD)的孔源性视网膜脱离中的作用。
    方法:我们比较了接受PPV(B组)或不重复IMTX(A组)的RRDCD眼的解剖和视觉结果。
    结果:该研究包括25名患者的25只眼,A组16只眼,B组9只眼,两组基线特征相似。A组,成功的视网膜附着达到50%,而B组为89%,但差异无统计学意义(p=0.08).此外,与A组(1.18+1logMAR单位)相比,B组从基线到最后一次随访(1.6+1.5logMAR单位)的视力变化显著更大(p=0.05)。使用IMTX没有重大的安全问题。
    结论:RRDCD玻璃体切除术后重复IMTX可改善预后,而不会引起重大安全性问题。尽管如此,需要进一步研究以确定最佳IMTX剂量和持续时间,从而有效预防复发.
    OBJECTIVE: To evaluate the role of repeated intravitreal methotrexate as an adjunct to pars plana vitrectomy in the management of rhegmatogenous retinal detachment with choroidal detachment.
    METHODS: The authors compared anatomical and visual outcomes of rhegmatogenous retinal detachment with choroidal detachment eyes that underwent pars plana vitrectomy with (Group B) or without repeated intravitreal methotrexate (Group A).
    RESULTS: The study included 25 eyes of 25 patients, 16 eyes in Group A and nine in Group B. Both groups had similar baseline characteristics. In Group A, successful retinal attachment was achieved in 50% as compared with 89% in Group B; however, the difference was not statistically significant ( P = 0.08). Also, Group B had a significantly greater change in visual acuity from baseline to the last follow-up visit (1.6 + 1.5 logMAR units) compared with Group A (1.18 + 1 logMAR units) ( P = 0.05). There were no significant safety concerns with the use of intravitreal methotrexate.
    CONCLUSIONS: Repeated intravitreal methotrexate after vitrectomy for rhegmatogenous retinal detachment with choroidal detachment improves outcomes without posing major safety concerns. Nonetheless, further investigation is necessary to establish the optimal intravitreal methotrexate dosage and duration to prevent recurrence effectively.
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  • 文章类型: Multicenter Study
    目的:报告临床设置,管理,以及与孔源性视网膜脱离并发脉络膜脱离的预后相关的因素。
    方法:回顾性,连续的,包括2014年1月至2021年1月的多中心病例系列。病例来自印度和台湾的三级眼保健中心。
    结果:共包括303只眼。平均年龄为43.72±20.64岁(中位数46)。最佳矫正视力为1.79±0.92logMAR(中位数2.10)(Snellen20/1,233)。44例患者(17.91%)接受术前类固醇治疗。最终视力为1.33±0.94logMAR(中位数1.10)(Snellen20/427)。有利的解剖结果见于200/303(66%),而有利的功能结局见于128/303(42.20%)。预测有利解剖结果的因素是无晶状体状态(比值比[OR]2.76),不存在比A级更差的增殖性玻璃体视网膜病变(OR7.69),术前使用类固醇(OR4.50),和使用环绕带(3.85)。预测良好功能结局的因素是视力表现更好(OR3.03),无晶状体状态(或4.93),不存在比A级更差的增殖性玻璃体视网膜病变(OR10.41),术前使用类固醇(OR7.24)。
    结论:术前使用类固醇,在手术期间使用环绕带,发现眼的假晶状体状态在孔源性视网膜脱离并发脉络膜脱离中具有更好的结果。
    OBJECTIVE: To report the clinical settings, management, and factors associated with outcomes of rhegmatogenous retinal detachment with concurrent choroidal detachment.
    METHODS: Retrospective, consecutive, multicenter case series from January 2014 to January 2021 were included. Cases were from a tertiary eye care center in India and Taiwan.
    RESULTS: Overall 303 eyes were included. Mean age was 43.72 ± 20.64 years (median 46). Best-corrected presenting visual acuity was 1.79 ± 0.92 logMAR (median 2.10) (Snellen 20/1,233). Forty-four patients (17.91%) received preoperative steroids. Final visual acuity was 1.33 ± 0.94 logMAR (median 1.10) (Snellen 20/427). Favorable anatomic outcome was seen in 200/303 (66%), whereas favorable functional outcome was seen in 128/303 (42.20%). Factors predicting favorable anatomic outcome were absence of phakic lens status (odds ratio [OR] 2.76), absence of proliferative vitreoretinopathy worse than Grade A (OR 7.69), use of preoperative steroids (OR 4.50), and use of an encircling band (3.85). Factors predicting favorable functional outcome were better presenting visual acuity (OR 3.03), absence of phakic lens status (OR 4.93), absence of proliferative vitreoretinopathy worse than Grade A (OR 10.41), and use of preoperative steroids (OR 7.24).
    CONCLUSIONS: Administration of preoperative steroids, use of an encircling band during surgery, and pseudophakic status of the eye were found to have better outcomes in rhegmatogenous retinal detachment with concurrent choroidal detachment.
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  • 文章类型: Journal Article
    背景技术视网膜和脉络膜联合脱离(RD-CD)在眼科治疗中提出了重大挑战。通常需要手术干预以获得最佳结果。选择合适的外科手术对于确保视觉恢复和整体眼睛健康至关重要。这项研究探讨了两种不同的RD-CD手术方法的治疗益处和结果:气压性视网膜固定术(PR),然后是平坦部玻璃体切除术(PPV)和单独的PPV。试图指导最佳的临床决策。材料与方法我们回顾性分析了64例诊断为RD-CD的连续患者的数据。他们分为两组:A组包括34例患者(34只眼),这些患者接受了PR作为初始治疗,随后接受了PPV,而B组,作为一个控制,包括30例仅接受PPV治疗的患者(30只眼)。结果A组应用PR显著加速眼压(IOP)升高(P.
    BACKGROUND Combined retinal and choroidal detachment (RD-CD) poses significant challenges in ophthalmic treatment, often requiring surgical intervention for optimal outcomes. The selection of the appropriate surgical procedure is crucial for ensuring visual restoration and overall eye health. This study delves into the therapeutic benefits and outcomes of two distinct surgical approaches for RD-CD: pneumatic retinopexy (PR) followed by pars plana vitrectomy (PPV) and PPV alone, in an attempt to guide optimal clinical decision-making. MATERIAL AND METHODS We retrospectively analyzed data from 64 consecutive patients diagnosed with RD-CD. They were categorized into two groups: Group A consisted of 34 patients (34 eyes) who underwent PR as an initial treatment and subsequently received PPV, while Group B, serving as a control, comprised 30 patients (30 eyes) treated solely with PPV. RESULTS The application of PR in Group A notably accelerated intraocular pressure (IOP) increase (P.
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  • 文章类型: Journal Article
    UNASSIGNED:为了研究术前脉络膜上腔曲安奈德(SCTA)的安全性和有效性,以实现与血源性视网膜脱离(RRD)相关的浆液性脉络膜脱离(CD)的减少/解决。
    未经批准:这是一个潜在的,非比较性,介入性试点研究。在进行玻璃体切除术/巩膜扣手术之前,所有连续出现RD和共存CD的患者均经结膜注射SCTA。进行顺序超声B扫描以评估CD高度的变化。
    未经证实:该队列的平均年龄为53.8±10.8岁(范围:39-72岁)。CD的中位数为3个象限;累积平均CD高度为5.59mm(范围:2.02-9.42mm)。在SCTA之后,在第3天时在5只眼睛中观察到成功的响应(>50%减少),在第5天时在2只眼睛中观察到成功的响应。三只眼睛对SCTA没有反应,在进行玻璃体切除术之前需要手术引流。术中无注射相关并发症。玻璃体切除术后,一只眼睛的眼内压(30mmHg)短暂升高,并通过局部抗青光眼药物成功治疗。
    UNASSIGNED:脉络膜上给药曲安奈德似乎是一种安全有效的技术,可以在RRD患者眼中实现CD分辨率。
    UNASSIGNED: To study the safety and efficacy of pre-operative suprachoroidal triamcinolone acetonide (SCTA) for achieving reduction/resolution of serous choroidal detachment (CD) associated with rhegmatogenous retinal detachment (RRD).
    UNASSIGNED: This was a prospective, noncomparative, interventional pilot study. All consecutive patients presenting with RD and coexisting CD underwent transconjunctival injection of SCTA before proceeding with vitrectomy/scleral buckle surgery. Sequential ultrasound B scans were performed for assessing the change in height of the CD.
    UNASSIGNED: The mean age of the cohort was 53.8 ± 10.8 years (range: 39-72 years). The CD was present in a median of 3 quadrants; the cumulative mean CD height was 5.59 mm (range: 2.02-9.42 mm). Following SCTA, a successful response (>50% reduction) was seen in five eyes by day 3 and in two eyes by day 5. Three eyes failed to respond to SCTA and required surgical drainage before proceeding with vitrectomy. No intraprocedural injection-related complications were noted. A transient rise in the intraocular pressure (30 mmHg) was seen in one eye following vitrectomy and was managed successfully with topical antiglaucoma medications.
    UNASSIGNED: Suprachoroidal administration of triamcinolone appears to be a safe and effective technique to achieve CD resolution in eyes with RRD.
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  • 文章类型: Journal Article
    OBJECTIVE: To investigate risk factors for choroidal detachment after trabeculectomy.
    METHODS: We prospectively evaluated 97 patients with open-angle glaucoma who underwent primary trabeculectomy to investigate risk factors for choroidal detachment after trabeculectomy. The primary outcome measure was risk factors for the occurrence and severity of choroidal detachment after trabeculectomy. Choroidal detachment severity was quantified as the number of fundus quadrants with choroidal detachment.
    RESULTS: Sixteen patients (16.5%) had choroidal detachment. Mean period between surgery and occurrence of choroidal detachment was 7.9 ± 5.7 days. Mean intraocular pressure (IOP) on the first day of choroidal detachment was 6.1 ± 3.0 mm Hg. Multivariable analyses revealed that the exfoliation glaucoma, greater ΔIOP between preoperative and lowest postoperative IOPs, and thicker cornea were associated with choroidal detachment (P = 0.022, P = 0.002, and P = 0.013, respectively). These factors were also associated with the severity of choroidal detachment (exfoliation glaucoma; P = 0.013, greater ΔIOP; P < 0.001, and thicker cornea; P = 0.006).
    CONCLUSIONS: Exfoliation glaucoma, more IOP reduction, and thicker cornea are associated with the occurrence and severity of choroidal detachment after trabeculectomy.
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