感染是全球发病率和死亡率的第二大原因,因此,研究头孢菌素等抗菌药物非常重要。头孢菌素,属于头孢菌素类的抗菌剂,具有杀菌活性,广泛用于巴西卫生系统。在文学中,找到了一些用于鉴定和定量该药物的分析方法,这对其质量控制至关重要,确保保持产品特性,治疗效果和患者的安全性。本文的目的是回顾有关头孢菌素分析方法的可用信息。因此,本研究提供了有关头孢菌素的文献综述,以及为官方和科学论文中分析该药物而开发的分析方法。重要的是要注意,大多数开发的方法使用有毒和有害的溶剂,这使得必要的行业和研究人员选择开发环保技术,这将有助于科学的协调,人类,和环境健康。
Infections are the second leading cause of global morbidity and mortality, therefore it is highly important to study the antimicrobial agents such as cephalosporins.
Cephalothin, an antimicrobial agent that belongs to the class of cephalosporins, has bactericidal activity and it is widely used in the Brazilian health system. In literature, some analytical methods are found for the identification and quantification of this drug, which are essential for its quality control, which ensures maintaining the product characteristics, therapeutic efficacy and patient\'s safety. The aim of this article is to
review the available information on analytical methods for
cephalothin. Thus, this study presents a literature
review on
cephalothin and the analytical methods developed for the analysis of this drug in official and scientific papers. It is essential to note that most of the developed methods used toxic and hazardous solvents, which makes necessary industries and researchers choose to develop environmental-friendly techniques, which will contribute to the harmonization of science, human, and environmental health.