背景:胰腺实性假乳头状肿瘤(SPN)是罕见的肿瘤,约占胰腺肿瘤的1%。它们主要在生殖阶段影响女性,并具有良好的预后。SPN通常无症状或存在轻度症状。SPN的确切组织病理学仍未知。手术切除是治愈性的,中央胰腺切除术是一种保留胰腺的手术技术。
方法:一名33岁的女性出现上腹痛,呕吐,和不孕症。成像显示胰腺有肿块。探索证实了质量,并进行了中央胰腺切除术。组织病理学证实了SPN的诊断。病人的康复顺利,随访CT扫描显示无复发。
结论:该病例涉及一名33岁女性,表现为上腹痛和呕吐,显示胰腺中有固体成分的囊性肿块。虽然通常是良性的,SPN在15%的病例中可以变成恶性的,预后良好。组织病理学,SPN仍然不同,CD99和CD10染色证实诊断。诊断成像,尤其是CT扫描,有助于识别SPN。手术切除,比如中央胰腺切除术,是有效的,保存器官功能。该病例的阳性结果与95-97%的总体5年生存率一致,强调SPN的总体良好预后。该方法在肿瘤切除和器官保存之间的平衡提供了临床优势。
结论:该病例强调了使用中央胰腺切除术成功治疗SPN。它强调了早期诊断和手术干预的重要性,以及与SPN相关的良好预后,即使在转移的情况下。中央胰腺切除术提供器官保存并减少长期并发症。对此类病例的持续报告和研究有助于完善SPN的治疗策略。
BACKGROUND: Solid pseudopapillary neoplasms (SPNs) of the pancreas are rare tumors, comprising about 1 % of pancreatic tumors. They primarily affect females during their reproductive phase and have a favorable prognosis. SPNs are usually asymptomatic or present with mild symptoms. The exact histopathogenesis of SPNs remains unknown. Surgical resection is curative, and central pancreatectomy is a pancreas-sparing surgical technique.
METHODS: A 33-year-old female presented with epigastric pain, vomiting, and infertility. Imaging revealed a mass in the pancreas. Exploration confirmed the mass, and central pancreatectomy was performed. Histopathology confirmed the diagnosis of SPN. The patient\'s recovery was uneventful, and follow-up CT scans showed no recurrence.
CONCLUSIONS: This
case involves a 33-year-old female presenting with epigastric pain and vomiting, revealing a cystic mass with a solid component in the pancreas. While generally benign, SPNs can become malignant in 15 % cases, with a favorable prognosis. Histopathologically, SPNs remain distinct, with CD99 and CD10 staining confirming the diagnosis. Diagnostic imaging, particularly CT scans, aids in identifying SPNs. Surgical resection, such as central pancreatectomy, is effective, preserving organ function. The
case\'s positive outcome aligns with an overall 5-year survival rate of 95-97 %, highlighting the overall favorable prognosis of SPNs. The procedure\'s balance between tumor removal and organ preservation offers clinical advantages.
CONCLUSIONS: This
case underscores the successful management of an SPN using central pancreatectomy. It highlights the importance of early diagnosis and surgical intervention, as well as the favorable prognosis associated with SPNs, even in cases of metastasis. Central pancreatectomy offers organ preservation and reduces long-term complications. Continued reporting and research on such cases contribute to refining treatment strategies for SPNs.