Case study

案例研究
  • 文章类型: Journal Article
    成团的泛菌,革兰氏阴性细菌,已经成为一种机会病原体,特别是在新生儿医疗机构中。最初被认为是无害的环境污染物,成团假单胞菌越来越多地参与一系列临床感染,包括新生儿败血症和菌血症。本系统综述对2003-2023年发表的临床病例进行了深入分析,阐明了与新生儿成群假单胞菌感染相关的多方面临床表现和治疗挑战。总的来说,包括来自八个不同国家的11例病例报告和45例新生儿病例系列。大多数感染患者(57.8%)在亚洲国家(斯里兰卡,印度,科威特),并涉及极低至低出生体重的早产儿(64.4%),以及并发的医疗状况,包括其中一些(15.6%)的合并感染。血液是病原体的主要培养源,占42例(91.1%),而新生儿的临床表现表现出相当大的异质性,包括常见的症状,如喂养困难,呼吸窘迫,发烧,嗜睡,还有败血症.新生儿的生存在很大程度上取决于感染的起源和诊断的时机。将抗生素敏感性作为治疗选择的标准导致74%的存活率。通常,使用了抗生素的组合。报告有11例新生儿死亡,导致估计死亡率为24.4%。我们得出的结论是,新生儿重症监护病房内的暴发强调了严格的感染控制措施和加强监测的重要性,特别是考虑到纳入的研究中提到的快速疾病进展。增强对聚集假单胞菌感染的临床和微生物学特征的认识和理解对于优化结果和减轻新生儿人群的疾病负担至关重要。
    Pantoea agglomerans, a gram-negative bacterium, has emerged as an opportunistic pathogen, particularly within neonatal healthcare settings. Initially perceived as an innocuous environmental contaminant, P. agglomerans has been increasingly implicated in a spectrum of clinical infections, including neonatal sepsis and bacteremia. This systematic review conducts an in-depth analysis of the clinical cases published in 2003-2023, elucidating the multifaceted clinical presentations and therapeutic challenges associated with P. agglomerans infections in neonates. In total, 11 case reports and case series of 45 neonates from eight different countries were included. Most of the infected patients (57.8%) were reported in Asian countries (Sri Lanka, India, Kuwait) and involved preterm neonates (64.4%) with extremely low to low birth weight, and concurrent medical conditions including co-infections in a few of them (15.6%). Blood was the main culture source of the pathogen, accounting for 42 cases (91.1%) whereas clinical presentations in neonates exhibited considerable heterogeneity, encompassing common symptoms such as feeding difficulties, respiratory distress, fever, lethargy, and sepsis. Neonatal survival largely depended on the infection\'s origin and the timing of diagnosis. Considering antibiotic susceptibility as a criterion for treatment selection led to a 74% survival rate. Usually, a combination of antibiotics was used. There were 11 neonatal deaths reported, leading to an estimated mortality rate of 24.4%. We conclude that outbreaks within neonatal intensive care units underscore the importance of stringent infection control practices and heightened surveillance, especially considering the rapid disease progression noted in the included studies. Enhanced awareness and understanding of the clinical and microbiological characteristics of P. agglomerans infections are paramount for optimizing outcomes and reducing the burden of disease in neonatal populations.
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    文章类型: Journal Article
    为了证明使用期刊文章报告标准的发表后同行评审如何改善运动学研究的设计和撰写,作者对2020年发表的一篇系统文献综述进行了发表后同行评价.两名评估者(第一和第二作者)在2021年4月至5月期间对案件文章进行了严格评估。使用了美国心理学协会与该评论相关的最新期刊文章报告标准:即,表1(定量研究标准)和表9(研究综合标准)。完全满足的标准被认为是令人满意的。根据克里普多夫的α系数,表1的评分者之间的协议中等(k-alpha=.57,原始协议=72.2%),表9的协议较差(k-alpha=.09,原始协议=53.6%)。对所有差异达成了100%的共识。结果表明,案例文章的摘要,Methods,和讨论部分需要澄清或更详细。根据表9标准,四个部分基本上是不完整的:即,摘要(100%-不完整),介绍(66%-不完整),方法(75%-不完整),和讨论(66%-不完整)。案例文章的优势包括系统评价中分析的研究的表格总结和对评价的概括性的警示性评论。本文的写作提供了细节,以帮助读者理解研究的范围和作者做出的决定。然而,没有提供足够的细节来评估该条中所有索赔的可信度。这可能会影响读者对文章主题的批判性和细致入微的理解。这种批评的结果应该鼓励(继续)对不同利益相关者的期刊文章报告标准进行教育(例如,作者,审稿人)。
    To demonstrate how post-publication peer reviews-using journal article reporting standards-could improve the design and write-up of kinesiology research, the authors performed a post-publication peer review on one systematic literature review published in 2020. Two raters (1st & 2nd authors) critically appraised the case article between April and May 2021. The latest Journal Article Reporting Standards by the American Psychological Association relevant to the review were used: i.e., Table 1 (quantitative research standards) and Table 9 (research synthesis standards). A standard fully met was deemed satisfactory. Per Krippendorff\'s alpha-coefficient, inter-rater agreement was moderate for Table 1 (k-alpha = .57, raw-agreement = 72.2%) and poor for Table 9 (k-alpha = .09, raw-agreement = 53.6%). A 100% consensus was reached on all discrepancies. Results suggest the case article\'s Abstract, Methods, and Discussion sections required clarification or more detail. Per Table 9 standards, four sections were largely incomplete: i.e., Abstract (100%-incomplete), Introduction (66%-incomplete), Methods (75%-incomplete), and Discussion (66%-incomplete). Case article strengths included tabular summary of studies analyzed in the systematic review and a cautionary comment about the review\'s generalizability. The article\'s write-up gave detail to help the reader understand the scope of the study and decisions made by the authors. However, adequate detail was not provided to assess the credibility of all claims made in the article. This could affect readers\' ability to obtain critical and nuanced understanding of the article\'s topics. The results of this critique should encourage (continuing) education on journal article reporting standards for diverse stakeholders (e.g., authors, reviewers).
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  • 文章类型: Journal Article
    背景:甲状腺手术继发的甲状腺组织植入或播散很少见。其中大多数属于甲状腺癌,具有转移潜力,在良性病理中并不常见。
    方法:我们报告了一例31岁女性,在经口内镜甲状腺切除术前庭入路5年后,发现甲状腺组织多次皮下植入。对甲状腺手术继发的甲状腺组织植入进行了全面的文献检索。
    结果:在之前的手术中意外撕裂胶囊可能导致皮下植入。通过文献综述,共纳入29篇文献,共47例患者.33.3%为良性病变,植入主要是继发于细针穿刺活检(46.5%)。
    结论:内镜甲状腺手术后皮下或端口植入可能发生在良性甲状腺病变中,因此,无论其组织病理学性质如何,手术期间都必须严格遵守肿瘤原则。
    BACKGROUND: Extrathyroid implantation or dissemination of thyroid tissue secondary to a thyroid procedure is rare. Most of these belonged to thyroid carcinoma with metastatic potential and uncommon for benign pathologies.
    METHODS: We report the case of a 31-year-old female who was identified to have multiple subcutaneous implantation of thyroid tissue 5 years after transoral endoscopic thyroidectomy vestibular approach. A comprehensive literature search on implantation of thyroid tissue secondary to thyroid procedures was performed.
    RESULTS: Accidental tearing of the capsule during previous surgery may lead to the subcutaneous implantation. Through literature review, a total 29 articles with 47 patients were identified. 33.3% were benign lesions, and implantation was mostly secondary to fine needle aspiration biopsy (46.5%).
    CONCLUSIONS: Subcutaneous or port site implantation after endoscopic thyroid surgery may occur in benign thyroid pathologies and therefore, oncologic principles must be strictly followed during surgery regardless of its histopathological nature.
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  • 文章类型: Review
    多发性骨髓瘤(MM)是一种与克隆性浆细胞增殖障碍相关的恶性疾病,以克隆浆细胞在骨髓中广泛浸润为特征,其中一部分患者预后不佳,早期没有明显症状。淀粉样变是由MM引起的罕见疾病。免疫球蛋白轻链淀粉样变性(AL)是由增殖的克隆B细胞或浆细胞分泌特定的毒性轻链蛋白引起的。这些轻链蛋白在人体组织中积累并导致器官功能障碍和衰竭。淀粉样变性的口腔表现包括巨舌,突出的语言边缘,彩色丘疹,紫癜,和结节状突起。描述和总结与AL淀粉样变相关的口腔表现,以达到准确的临床诊断。我们介绍了一例与多发性骨髓瘤相关的AL淀粉样变性病例,并回顾了从Medline开始发现的其他相关病例的文献。一位女性患者患有深舌头溃疡。口腔活检和组织染色后,结合血液内科的检查结果,患者被诊断为与多发性骨髓瘤相关的口服AL淀粉样变性.这是对潜伏性MM继发于孤立性舌头溃疡的AL淀粉样变性的第一例研究。慢性口腔难治性溃疡可能与全身性疾病有关,应在今后的临床实践中加以考虑。
    Multiple myeloma (MM) is a malignant disease associated with clonal plasma cell proliferative disorder, characterized by extensive infiltration of clonal plasma cells in the bone marrow, for which a proportion of patients suffer poor outcome and exhibit no obvious symptoms in the early stages. Amyloidosis is a rare condition caused by MM. Immunoglobulin light chain amyloidosis (AL) is caused by the secretion of specific toxic light chain proteins from proliferating clonal B cells or plasma cells. These light chain proteins accumulate in human tissues and cause organ dysfunction and failure. Oral manifestations of amyloidosis include macroglossia, prominent lingual margins, coloured papules, purpura, and nodular protrusions. To describe and summarize the oral manifestations associated with AL amyloidosis in order to achieve an accurate clinical diagnosis. We present a case of AL amyloidosis associated with multiple myeloma and review the literature on other related cases identified from the inception of Medline. A female patient visited our clinic with a deep tongue ulcer. After oral biopsy and tissue staining, combined with the examination results from the Department of Haematology, the patient was diagnosed with oral AL amyloidosis related to multiple myeloma. This is the first case study of AL amyloidosis secondary to latent MM presenting as a solitary tongue ulcer. Chronic oral refractory ulcers may be associated with systemic diseases and should be considered in future clinical practice.
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  • 文章类型: Journal Article
    作为涡轮机(PAT)的泵以其取代Pico/微型水力发电厂中的常规涡轮机的能力而闻名。然而,选择一个合适的泵和估计其性能在反向模式是一个具有挑战性的任务。与专用涡轮机相比,PAT的整体效率也较低。已经进行了许多尝试来分析PAT在发电应用中的性能,许多学者对绩效改进和经济分析进行了研究。在本文中,进行了详细的回顾,以显示PAT技术的历史发展和现状。这篇综述还介绍了业绩预测的结果,性能改进技术,和经济分析。文献调查的结果表明,为特定应用选择合适的泵会显著影响PAT系统的性能。在各种选择中,剪切应力传输(SST)k-ω和标准k-ε湍流模型被广泛用于模拟作为涡轮机的泵。叶片开槽和叶尖圆化是公认的最有前途的提高效率技术,收益分别为4.91%和4.00%,分别。除叶轮直径修边外,各种学者提出的叶片改型技术对PAT的效率有重大影响;然而,需要进一步的研究来探讨叶轮改造的经济优势。
    Pumps as Turbines (PATs) are known for their ability to replace conventional turbines in Pico/micro-hydropower plants. However, selecting a suitable pump and estimating its performance in reverse mode is a challenging task. The overall efficiency of PATs is also lower when compared to purpose-made turbines. Numerous attempts have been made to analyze the performance of PAT in power-generating applications, and many scholars have presented their research on performance improvement and economic analysis. In this paper, a detailed review is conducted to show the historical development and current status of PAT technology. The review also presents the findings of performance prediction, performance improvement techniques, and economic analysis. The results of the literature survey demonstrate that the choice of an appropriate pump for a specific application significantly affects the performance of the PAT system. Among the various options, the Shear Stress Transport (SST) k-ω and standard k-ε turbulence models are widely used for simulating the pump as a turbine. Blade grooving and blade tip rounding are recognized as the most promising techniques for improving efficiency, with gains of 4.91% and 4.00%, respectively. Except for impeller diameter trimming, blade modification techniques proposed by various scholars have a significant impact on the efficiency of PATs; however, further research is needed to investigate the economic advantages of impeller modification.
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  • 文章类型: Case Reports
    延伸到前髂下棘的髋臼前壁骨折更容易不稳定,更有可能需要手术固定。
    常规髋臼前壁骨折起源于前髂下棘(AIIS)水平以下,并累及骨盆边缘。由于不稳定和髋关节不一致保留了手术治疗,这种骨折的非典型变异通常会危及髋关节稳定性。我们报告了一例33岁的髋臼前壁骨折延伸到前髂下棘的病例。他做好了压力测试和髋关节稳定性检查的准备,延伸和外部旋转不稳定。史密斯-彼得森方法暴露了关节。髋关节一致性恢复了,通过开放还原稳定AIIS片段。涉及AIIS并保留骨盆边缘的髋臼前壁骨折是一种罕见的前壁骨折,会危害髋关节稳定性,应手术治疗。为了使关节可视化,首选前路。
    UNASSIGNED: Anterior acetabular wall fractures that extend into the anterior inferior iliac spine are more likely to be unstable, and more likely to require surgical fixation.
    UNASSIGNED: Conventional acetabular anterior wall fractures originate below the anterior inferior iliac spine (AIIS) level and involve the pelvic brim. Since surgical treatment is preserved for instability and hip incongruency, atypical variation of this fracture usually jeopardizes hip stability. We report on a 33-year-old case of an acetabular anterior wall fracture extending to the anterior inferior iliac spine. He was prepared for the stress test and hip stability checked, that was unstable in extension and external rotation. The joint was exposed with the Smith-Peterson approach. Hip congruency was restored, and the AIIS fragment was stabilized by open reduction. Acetabular anterior wall fracture involving AIIS with preservation of pelvic brim is a rare equivalent of anterior wall fracture that jeopardizes hip stability and should be managed surgically. Anterior approaches are preferred in order to visualize the joint.
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  • 文章类型: Review
    BACKGROUND: Posttraumatic stress disorder (PTSD) can induce an elevation in sympathetic tone; however, research pertaining to the cardiac cycle in patients with PTSD is limited.
    METHODS: A literature review was conducted with PubMed, MEDLINE and Web of Science. Articles discussing changes and associations in echocardiography and PTSD or related symptoms were synthesized for the current review. We have also included data from a case report of a male participant aged 33 years experiencing potentially psychologically traumatic events, who wore a noninvasive cardiac sensor to assess the timing intervals and contractility parameters of the cardiac cycle using seismocardiography. The intervals included systolic time, isovolumic contraction time (IVCT) and isovolumic relaxation time (IVRT). Calculations of systolic (IVCT/systole), diastolic (IVRT/systole) and myocardial [(IVCT+IVRT)/systole] performance indices were completed.
    RESULTS: The review identified 55 articles, 14 of which assessed cardiac function using echocardiography in patients with PTSD symptoms. Cardiac dysfunction varied across studies, with diastolic and systolic impairments found in patients with PTSD. Our case study showed that occupational stress elevated cardiac performance indices, suggesting increased ventricular stress and supporting results in the existing literature.
    CONCLUSIONS: The literature review results suggest that a controlled approach to assessing cardiac function in patients with PTSD is required. The case study results further suggest that acute bouts of stress can alter cardiac function, with potential for sustained occupational stress to induce changes in cardiac function. Cardiac monitoring can be used prospectively to identify changes induced by potentially psychologically traumatic event exposures that can lead to the development of PTSD symptoms.
    BACKGROUND: Alors qu’on sait que le trouble de stress post-traumatique (TSPT) peut entraîner une augmentation du tonus sympathique, ses effets sur le cycle cardiaque ont été peu étudiés.
    UNASSIGNED: Nous avons réalisé une revue de la littérature en interrogeant les bases de données PubMed, MEDLINE et Web of Science. Les articles traitant des modifications de nature échocardiographique en lien avec le TSPT ou des symptômes connexes et traitant des associations entre les deux ont été synthétisés pour cette revue de la littérature. Nous avons également inclus les données d’une étude de cas dans laquelle les intervalles de temps et les paramètres de contractilité du cycle cardiaque ont été évalués par séismocardiographie chez un participant âgé de 33 ans qui portait un capteur cardiaque non invasif et qui a été exposé à des événements potentiellement traumatiques sur le plan psychologique. Les intervalles évalués étaient le temps de systole, le temps de contraction isovolumique (TCIV) et le temps de relaxation isovolumique (TRIV). Nous avons calculé les indices de performance systolique (TCIV/systole), diastolique (TRIV/systole) et myocardique [(TCIV+TRIV)/systole].
    UNASSIGNED: La revue de la littérature a permis de recenser 55 articles, dont 14 portant sur l’évaluation de la fonction cardiaque par échocardiographie chez des patients présentant des symptômes de TSPT. La dysfonction cardiaque variait selon les études, avec la présence d’atteintes diastoliques et systoliques chez des patients ayant un TSPT. L’étude de cas montre que le stress lié au travail augmente les indices de performance cardiaque, ce qui évoque un stress ventriculaire accru et vient confirmer les résultats dont on dispose dans la littérature.
    CONCLUSIONS: D’après les résultats de notre revue de la littérature, l’évaluation de la fonction cardiaque chez les patients atteints de TSPT devrait faire l’objet d’une approche contrôlée. Quant à l’étude de cas, les résultats laissent penser que les épisodes de stress aigu peuvent altérer la fonction cardiaque et que le stress prolongé lié au travail pourrait induire des changements dans la fonction cardiaque. Il est possible d’utiliser la surveillance cardiaque de façon prospective pour déceler les changements provoqués par une exposition à des événements potentiellement traumatiques sur le plan psychologique, cette exposition pouvant conduire au développement de symptômes de TSPT.
    Research on cardiac cycle timing intervals and posttraumatic stress disorder (PTSD) is very limited. Systolic and diastolic dysfunction is documented in PTSD; however, there is much variation in the literature on cardiac function in PTSD. Potentially psychologically traumatic events (PPTE) can increase myocardial performance index, in part due to shortened systolic time. PPTE can result in elevated cardiac stress, and this can be easily and noninvasively monitored using seismocardiography.
    Il y a peu de recherche sur les intervalles de temps du cycle cardiaque et le trouble de stress post-traumatique (TSPT). Des dysfonctions systoliques et diastoliques ont été observées en lien avec un TSPT, mais la littérature s’intéressant à la fonction cardiaque en contexte de TSPT est très hétéroclite. L’exposition à des événements potentiellement traumatiques sur le plan psychologique peut entraîner une augmentation de l’indice de performance myocardique, laquelle relève en partie d’une réduction du temps de systole. L’exposition à des événements potentiellement traumatiques sur le plan psychologique est susceptible de mener à une hausse du stress cardiaque, ce que la séismocardiographie permet de surveiller facilement et de manière non invasive.
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  • 文章类型: Journal Article
    本文的目的有两个:首先,概述支持协作学习的新兴数字实践,能力发展,以及在全球与大流行相关的封锁导致的快速数字过渡期间,高等教育中以学生为中心的学习环境的数字素养,其次,分析和讨论如何将对广义主题和趋势的系统审查与情境化的经验和从新冠肺炎危机中吸取的教训相结合,为高等教育的数字化转型提供信息,特别注重弥合校园教学和在线学习之间的差距,以及确定教师和学生在继续转变为大流行后教育实践的“新常态”期间必须获得的数字能力。这项研究的动机是由这篇论文的三位合著者(Lyngdorf等人。,2021a)。通过查阅18条的全文,这项研究提供了一个系统的文献综述,绘制了在线的一般景观,混合动力车,以及自疫情爆发以来,在高等教育中现有的以学生为中心的学习环境中应用的混合数字实践。此外,该映射用于重新访问早期在特定的基于问题和基于项目的学习(PBL)环境中对新兴数字实践进行的被动研究的数据和发现。这项研究的发现强调了与支持学生与教师互动的新兴实践相关的关键因素和障碍。内容,和彼此,以及这些实践将需要的新兴能力。本文最后讨论了主要发现及其对进一步研究和实践的启示。
    The aim of this paper is two-fold: firstly, to provide an overview of emerging digital practices that support collaborative learning, competency development, and digital literacy for student-centered learning environments in higher education during the rapid digital transition caused by pandemic-related lockdowns across the world, and secondly, to analyze and discuss how systematic reviews of generalized themes and trends can be combined with contextualized experiences and the lessons learned from the Covid-19 crisis to inform the digital transformation of higher education, with a particular focus on bridging the gap between campus-based teaching and online learning and on the identification of the digital competencies that teachers and students must acquire during the continuing shift into a \'new normal\' for post-pandemic educational practices. This study was motivated by questions and findings emerging from an early reactive case study conducted by three of this paper\'s co-authors (Lyngdorf et al., 2021a). By reviewing the full texts of 18 articles, this study provides a systematic literature review which maps the general landscape of the online, hybrid, and blended digital practices applied in existing student-centered learning environments in higher education since the onset of the pandemic. Furthermore, this mapping is used to revisit data and findings from the earlier reactive study of emerging digital practices in a specific problem- and project-based learning (PBL) environment. This study\'s findings highlight critical factors and barriers related to emerging practices which support students\' interactions with teachers, content, and each other, as well as the emerging competencies that these practices will require. The paper concludes with a discussion of the main findings and their implications for further research and practice.
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  • 文章类型: Journal Article
    目标:本研究考察了冰岛预防模式(IPM)在加拿大的实施情况,以确定COVID-19大流行揭示的重新设计我们的社会生态系统以促进福祉的机会。本文有两个目标:1)对将生物生态模型应用于青少年物质使用预防的研究进行概念性审查,重点是时间和物理空间使用的概念;2)描述一个案例研究,该案例研究在COVID-19大流行的背景下,加拿大的IPM的实施。
    方法:通过与参与实施IPM的关键利益相关者进行半结构化定性访谈来收集研究数据。
    结果:研究结果由主题分析得出的三个总体主题组成:1)影响时间和空间使用模式以及青年物质使用的问题,2)家庭和社区凝聚力以及对发展环境和时间使用的影响,以及3)大流行带来的可以促进青年福祉的机会。
    结论:我们将研究结果应用于IPM和大流行的研究,以检查可能支持一级预防和整体青年福祉的机会。我们使用时间和空间的概念作为基础来讨论对未来政策和实践的影响。
    OBJECTIVE: This research examines the implementation of the Icelandic Prevention Model (IPM) in Canada to identify opportunities revealed by the COVID-19 pandemic to re-design our social eco-system to promote wellbeing. This paper has two objectives: 1) to provide a conceptual review of research that applies the bioecological model to youth substance use prevention with a focus on the concepts of time and physical space use and 2) to describe a case study that examines the implementation of the IPM in Canada within the context of the COVID-19 pandemic.
    METHODS: Study data were collected through semi-structured qualitative interviews with key stakeholders involved in implementing the IPM.
    RESULTS: Findings are organized within three over-arching themes derived from a thematic analysis: 1) Issues that influence time and space use patterns and youth substance use, 2) Family and community cohesion and influences on developmental context and time use and 3) Opportunities presented by the pandemic that can promote youth wellbeing.
    CONCLUSIONS: We apply the findings to research on the IPM as well as the pandemic to examine opportunities that may support primary prevention and overall youth wellbeing. We use the concepts of time and space as a foundation to discuss implications for policy and practice going forward.
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  • 文章类型: Meta-Analysis
    迄今为止,通过临床和神经影像学研究,小脑对语言的贡献得到了很好的证实。然而,小脑在语言中的特殊功能作用还有待澄清。在这项研究中,我们对过去30年在案例研究中报道的小脑病变后口语中的各种语言症状进行了首次系统综述(13篇论文中的18例临床病例),和荟萃分析,采用聚类分析和自举法和症状共现分析。发现小脑病变后语言症状相似的七组患者。共现分析显示,成对的症状往往是合并症。我们的结果表明,“语言小脑”对语言功能具有多种形式的贡献。这种贡献的最可能机制是小脑与幕上大脑区域的相互连通性,其中语言网络的小脑水平具有一般的调制功能,而幕上水平则在功能上得到了更多的指定。基于小脑与语言网络的幕上成分的连通性,“语言小脑”可能在功能上进一步隔离。
    To date, cerebellar contribution to language is well established via clinical and neuroimaging studies. However, the particular functional role of the cerebellum in language remains to be clarified. In this study, we present the first systematic review of the diverse language symptoms in spoken language after cerebellar lesion that were reported in case studies for the last 30 years (18 clinical cases from 13 papers), and meta-analysis using cluster analysis with bootstrap and symptom co-occurrence analysis. Seven clusters of patients with similar language symptoms after cerebellar lesions were found. Co-occurrence analysis revealed pairs of symptoms that tend to be comorbid. Our results imply that the \"linguistic cerebellum\" has a multiform contribution to language function. The most possible mechanism of such contribution is the cerebellar reciprocal connectivity with supratentorial brain regions, where the cerebellar level of the language network has a general modulation function and the supratentorial level is more functionally specified. Based on cerebellar connectivity with supratentorial components of the language network, the \"linguistic cerebellum\" might be further functionally segregated.
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