马来西亚念珠菌属感染的流行病学和抗真菌敏感性数据仍然有限。该研究旨在回顾和比较马来西亚半岛念珠菌属感染的流行率和抗真菌易感性的研究。数据来自2009年至2018年发表的22项研究。数据是使用国家生物技术信息中心和Google学者使用关键字“念珠菌和马来西亚”收集的。“在这些研究中,总共分析了35,608个念珠菌分离株中,大约有19个念珠菌被鉴定出来。在大多数研究中,白色念珠菌(66.3%)是主要物种,其次是C.glabrata(11.7%),C.近平滑(10.7%),C.热带肌(9.5%),和C.krusei(1.19%)。阴道拭子产生的分离株最多,其次是呼吸系统,尿液,血,口服,脓液,和其他地点。人口统计,种族,性别数据仅记录在两项研究中.完全正确,8项研究检测了396个分离株对常见抗真菌药物的抗真菌敏感性.对于最常见的抗真菌药物,这些研究中分离株的平均抗真菌敏感性和药物功效在45%至99%之间。卡泊芬净的易感性最高,为99%,而伊曲康唑最低,仅为45%。总的来说,这篇综述全面总结了马来西亚半岛主要念珠菌的所有最新研究。
Data on the epidemiology and the antifungal susceptibility of Candida species infections in Malaysia is still limited. The study aimed to
review and compare studies reporting the prevalence of Candida species and antifungal susceptibility of Candida infections in Peninsular Malaysia. Data from 22 studies published between 2009 and 2018. Data was collected using National Center for Biotechnology Information and Google Scholar using the keywords \"Candida and Malaysia.\" Around 19 Candida species were identified in a total of 35,608 Candida isolates analyzed in these studies. In most studies examined, C. albicans (66.3%) was the predominant species, followed by C. glabrata (11.7%), C. parapsilosis (10.7%), C. tropicalis (9.5%), and C. krusei (1.19%). Vaginal swabs yielded the most isolates, followed by the respiratory system, urine, blood, oral, pus, and other locations. The demographic, racial, and gender data were recorded only in two studies. Totally, eight studies examined 396 isolates for antifungal susceptibility to common antifungal medications. The average antifungal susceptibility of isolates and efficacy of drugs in these studies ranged between 45 and 99% for most common antifungal drugs. Caspofungin had the highest susceptibility at 99%, whereas itraconazole had the lowest at only 45%. Overall, this
review provided a comprehensive summary of all the current research on predominant Candida species in Peninsular Malaysia.