糖尿病是世界范围内具有严重和危及生命的并发症和流行比例的疾病。骨骼糖尿病的研究可以为法医实践提供重要信息，考古领域和医学研究。在本文中,作者报告并讨论了在CALMilano公墓骨骼收藏中38例已知糖尿病患者的骨骼上观察到的病变（加上11例阴性对照样本）。因此,不同类型的病变在足部突出:骨膜新骨形成，毛簇的裂解，溶血性病变，创伤的证据,骨髓炎,和剥脱性骨软骨炎。在研究样本的50％的骨骼中，病变位于足部第一射线的骨骼上。还收集并考虑了血管钙化。这些病变中没有一个是糖尿病的病理标志，每个病变都意味着可以面对上部和轴向病变的广泛鉴别诊断。然而,它们与疾病的发展和并发症有关。这项研究是第一个从确定的集合中记录已知糖尿病的骨骼并讨论其诊断潜力的研究。
Diabetes mellitus is a condition with severe and life-threatening complications and epidemic proportions worldwide. The
study of diabetes on bones can provide crucial information to the forensic practice, the archeological field and medical research. In this paper, the authors report and discuss the lesions observed on the skeletons of 38 individuals (plus 11 negative control samples) of the CAL Milano Cemetery Skeletal Collection with known diabetes. As a result, different types of lesions were highlighted in the feet: periosteal new bone formation, lysis of tuft, lytic lesions, evidence of trauma, osteomyelitis, and osteochondritis dissecans. In 50% of the skeletons of the
study sample, lesions were located on bones of the first ray of the foot. Vascular calcifications were also collected and considered. None of these lesions is pathognomonic of diabetes and each implies a broad differential diagnosis that can be confronted with the upper and axial lesions. However, they are coherent with the disease development and complications. This
study is the first to document skeletons with known diabetes from an identified collection and discuss their diagnostic potential.
