基底细胞癌(BCC)仍然是世界上最常见的恶性肿瘤。BCC的发病机制是一个人的环境之间相互作用的结果,遗传学,和表型因素。BCC死亡率低,但由于其发病率不断增加,并有可能造成局部破坏,从而导致大量发病率。对于皮肤科医生来说,保持这种恶性肿瘤的发病机制和治疗的最新发展是至关重要的。本文对BCC的发病机制以及当前可用的治疗方法和正在进行的临床试验进行了全面的综述。我们还谈到了关于BCC推荐治疗方式的最新国家综合癌症网络肿瘤学临床实践指南。
Basal cell carcinoma (BCC) remains the most common malignancy worldwide. BCC pathogenesis is a result of the interplay between one\'s environment, genetics, and phenotypic factors. BCC has a low mortality but given its increasing incidence and potential to cause local destruction thus resulting in significant morbidity, it is vital for dermatologists to remain up to date with recent updates in this malignancy\'s pathogenesis and treatment. This article provides a comprehensive
review of the pathogenesis of BCC as well as the current treatments available and clinical trials underway. We also touch upon the updated National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology in respect to BCC\'s recommended treatment modalities.