Balantioidescoli是一种感染不同宿主物种的原生动物，包括人类,人畜共患传播。寄生虫,它生活在大肠和其他器官中，可能导致严重感染，最终导致死亡。关于人类balantidiasis的信息通常仍然很少。鉴于上述情况,这项研究的目的是分析流行病学，基于系统评价和荟萃分析的人类鲍兰迪病的临床和实验室特征。科学论文从各种数据库中检索，并进行了描述性分析，卡方检验,并在森林地块和异质性指数(I2)上进行了总结。共有103篇文章符合条件，并纳入本评论。在这103篇文章中，75是临床病例报告，28是流行病学研究，表明997（3.98%）人可能感染大肠杆菌。所分析文章的发表日期为1910年至2020年，但大多数（68.9％）是在1998年至2020年之间发表的。其中相当多的文章在南美和亚洲发表，主要在巴西和印度，分别。然而,在非洲,埃塞俄比亚,观察到感染人数较高(47.5%)。与猪的接近度与大肠杆菌的阳性之间存在显着关联（p<0.05）。因为超过16%的感染者靠近猪和/或它们的排泄物。原生动物的感染主要被归类为肠道，主要症状是痢疾。在27个人中发现了肠外感染，泌尿生殖道定植经常突出。直接检查（17.2%），其次是直接检查和沉降的关联(45.7%)，是最常用的寄生虫学技术，最常见的诊断形式是滋养体，相当于22.5%的病例。对被寄生个体最常见的治疗（11.8％）是四环素药物与硝基咪唑衍生物的关联。检索到的文章,主要是流行病学的，用于荟萃分析显示高度异质性(I2>50%，p<0.05)，影响结果的检索和比较。一些文章被发现提供了不完整的信息，这使得检索和分析变量变得困难。然而,这篇综述使我们能够汇编和重述似乎与人类鲍兰迪虫病病例相关的因素。
Balantioides coli is a protozoan that infects different hosts species, including humans, with zoonotic transmission. The parasite, which lives in the large intestine and in other organs, can lead to serious infections that may culminate in death. Information about human balantidiasis is generally still very scanty. In view of the above, the purpose of this study was to analyze the epidemiological, clinical and laboratory characteristics of human balantidiasis based on a systematic
review and meta-analysis. The scientific articles were retrieved from various databases and were subjected to descriptive analyses, chi-squared tests, and summarized on a forest plot and the heterogeneity index (I2). A total of 103 articles were eligible and included in this
review. Out of these 103 articles, 75 were clinical case reports and 28 were epidemiological studies, indicating a frequency of 997 (3.98%) people potentially infected with B. coli. The publication dates of the analyzed articles ranged from 1910 to 2020, but the majority (68.9%) were published between 1998 and 2020. A considerable number of these articles were published in South America and Asia, mostly in Brazil and India, respectively. However, in Africa, Ethiopia, was observed the higher number of infected people (47.5%). A significant association (p < 0.05) was identified between proximity to pigs and positivity for B. coli, since more than 16% infected people were in proximity with pigs and/or their excreta. Infection by the protozoan was classified mainly as intestinal, and the predominant symptom was dysentery. Extraintestinal infections were found in 27 individuals, with colonization of the genitourinary tract frequently highlighted. Direct examination (17.2%), followed by an association of direct examination and sedimentation (45.7%), were the most commonly performed parasitological techniques, and the most frequently diagnosed form was trophozoites, corresponding to 22.5% of cases. The most common treatment for parasitized individuals (11.8%) was an association of tetracycline drugs with nitroimidazole derivatives. The articles retrieved, mainly epidemiological ones, used in meta-analysis showed high heterogeneity (I2> 50%, p < 0.05), impairing the retrieval and comparison of results. Some articles were found to provide incomplete information, making it difficult to retrieve and analyze variables. However, this
review enabled us to compile and restate factors that appear to be associated with cases of human balantidiasis.
