动脉粥样硬化性心血管疾病(ASCVD)是全球范围内的主要杀手和医疗保健负担。动脉粥样硬化,共同的病理基础,在过去的几年里与炎症有关。也出现了一些有希望的结果,表明靶向炎症作为减少心血管事件的潜在治疗选择的作用。鉴于炎症在ASCVD中的致病作用,我们建议使用文献计量学分析评估ASCVD和炎症的全球研究架构.
■对2012年至2022年之间发布的该领域的文章进行了搜索。通过时间使用GraphPadPrism可视化了每年的出版物数量。CiteSpace和VOSviewer用于生成有关国家合作的知识图,机构,和作者,代表ASCVD和炎症研究的景观,并揭示当前的病灶。
■本研究共检查了19,053篇出版物。大多数出版物来自中国(6232,32.71%)。首都地中海大学是生产力最高的机构(410,2.15%)。ChristianWeber发表了最多的文章(75,0.39%)。PLoSone被确定为最多产的期刊(706,3.71%)。《循环》是被共同引用最多的期刊(13276,2.81%)。持续强烈引用爆发的关键词是“核苷酸结合寡聚化(NOD),含富含亮氨酸重复序列(LRR)的蛋白质(NLRP3)炎性体“,“肠道微生物群”,\"exosome\",\"lncRNAs\",等。
■可以表明,ASCVD和炎症研究得益于对科学界产生高度影响的手稿。亚洲人,欧洲和北美国家在数量上占主导地位,定性和协作参数。NLRP3炎性体,肠道菌群和三甲胺N-氧化物,自噬,lncRNAs,外泌体,和核因子红系2相关因子2被描述为该领域的热门主题。
UNASSIGNED: The atherosclerotic cardiovascular disease (ASCVD) is a major killer and health care burden worldwide. Atherosclerosis, the common pathological foundation, has been associated with inflammation over the past few years. Some promising results also have emerged suggesting the role of targeting inflammation as a potential therapeutic option to reduce cardiovascular events. In light of the pathogenic role that inflammation plays in ASCVD, we propose to evaluate the worldwide research architecture for ASCVD and inflammation using bibliometric analysis.
UNASSIGNED: A search of the Web of Science Core Collection of Clarivate Analytics was performed for articles in the field published between 2012 and 2022. The number of publications per year has been visualized using GraphPad Prism through time. CiteSpace and VOSviewer were used to generate knowledge maps about the collaboration of countries, institutions, and authors, and to represent the landscape on ASCVD and inflammation research as well as to reveal current foci.
UNASSIGNED: There were a total of 19,053 publications examined in this
study. The most publications came from China (6232, 32.71%). Capital Med Univ was the most productive institution (410, 2.15%). Christian Weber published the greatest number of articles (75, 0.39%). PloS one was identified as the most prolific journal (706, 3.71%). Circulation was the most co-cited journal (13276, 2.81%). Keywords with the ongoing strong citation bursts were \"nucleotide-binding oligomerization (NOD), Leucine-rich repeat (LRR)-containing protein (NLRP3) inflammasome\", \"intestinal microbiota\", \"exosome\", \"lncRNAs\", etc.
UNASSIGNED: It can be shown that ASCVD and inflammation research benefited from manuscripts that had a high impact on the scientific community. Asian, European and North American countries dominated in the field in terms of quantitative, qualitative and collaborative parameters. The NLRP3 inflammasome, gut microbiota and trimethylamine N-oxide, autophagy, lncRNAs, exosomes, and nuclear factor erythroid 2-related factor 2 were described to be hot themes in the field.