Arthroplasty, Replacement, Knee

关节成形术,更换,膝盖
  • 文章类型: Journal Article
    目的:在有TKA康复经验的荷兰物理治疗师中,探索并更深入地了解全膝关节置换术(TKA)患者的常规术前和术后物理治疗(PT)治疗。其次,评估物理治疗师对术后康复指南建议的依从性。
    方法:在这项横断面研究中,在线调查了在荷兰指定医院集水区的初级保健工作的物理治疗师。调查询问术前PT治疗方法,住院期间,手术后。对所有数据进行描述性分析。当教育和所有推荐的运动方式都在术后使用时,治疗师被认为完全遵守荷兰临床实践指南。
    结果:一百零三名治疗师参加了,代表58%的应答率。所有治疗师都进行了术后PT治疗,其中65人(63.1%)完全遵守指南。部分依从性主要是由于不使用有氧运动方式。此外,除了准则中建议的模式之外,采用了一系列PT干预措施.术前治疗有73名(70.9%)。这些73表明,只有中位数为20%(IQR10%-40%)的患者接受了术前PT。
    结论:这项研究显示,在有经验的物理治疗师中,TKA患者术后管理的指南建议得到了令人满意的遵守。有氧运动的使用频率较低或强度不适当。正确遵守关于有氧运动训练的指南建议可以导致更多的身体活跃的个体和重要的一般健康益处。
    OBJECTIVE: To explore and gain more insight into the usual preoperative and postoperative physical therapy (PT) treatment of patients with a total knee arthroplasty (TKA) among Dutch physical therapists experienced with TKA rehabilitation. Secondly, to evaluate physical therapists\' adherence to guideline recommendations for postoperative rehabilitation.
    METHODS: In this cross-sectional study, physical therapists working in primary care within a designated Dutch hospital\'s catchment area were surveyed online. The survey queried PT treatment approaches before surgery, during hospitalisation, and after surgery. All data were analysed descriptively. When both education and all recommended exercise modalities were used postoperatively, therapists were considered fully adherent with the Dutch clinical practice guideline.
    RESULTS: One hundred and three therapists participated, representing a response rate of 58%. Postoperative PT treatment was applied by all therapists, of which 65 (63.1%) were fully adherent to the guideline. Partial adherence was mainly due to not using the aerobic exercise modality. Furthermore, beyond the modalities recommended in the guideline, a range of PT interventions were used. Preoperative treatment was applied by 73 therapists (70.9%). These 73 indicated that only a median of 20% (IQR 10%-40%) of their patients received preoperative PT.
    CONCLUSIONS: This study revealed satisfactory adherence to guideline recommendations on postoperative management of patients with a TKA among experienced physical therapists. Aerobic exercises were utilised less often or with inappropriate intensity. Correct adherence to guideline recommendations on aerobic exercise training can result in more physically active individuals and important general health benefits.
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  • 文章类型: Journal Article
    预防可避免的静脉血栓栓塞(VTE)是改善全髋关节和全膝关节置换术后患者和服务结果的优先事项(THA,TKA),但对相关临床指南的遵守情况各不相同。本研究旨在确定预防符合澳大利亚骨科协会(AOA)VTE预防指南的程度,以及不依从性是否与VTE风险增加相关。在19家大型公立和私立医院完成了一项对接受原发性TKA/THA的骨关节炎成人的前瞻性多中心队列研究。在手术前和手术后一年收集数据。进行Logistic回归以探讨不遵守AOAVTE预防指南与有症状的90天VTE结局之间的关联。分析了来自19个地点的1838名参与者的数据。不符合所有临床指南建议的比率为20.1%(N=369),14.1%(N=259)不遵守风险分层预防,35.8%(N=658)的持续时间,其他一般性建议为67.8%(N=1246)。48人(2.6%)在手术后90天内经历了症状性VTE。总体指南不依从性(AOR=0.93,95CI=0.4至1.3,p=0.86)与有症状的90天VTE风险较低无关。当排除高出血风险人群时,结果是一致的(AOR=0.94,95CI=0.44至2.34,p=0.89)。不遵守AOAVTE预防指南与关节置换术后90天VTE的风险无关。这一违反直觉的发现令人担忧,需要对AOAVTE预防临床指南进行严格审查。
    Preventing avoidable venous-thrombo-embolism (VTE) is a priority to improve patient and service outcomes after total hip and total knee arthroplasty (THA, TKA), but compliance with relevant clinical guidelines varies. This study aims to determine the degree to which prophylaxis was compliant with Australian Orthopaedic Association (AOA) VTE prophylaxis guidelines and whether non-compliance is associated with increased risk of VTE. A prospective multi-centre cohort study of adults with osteoarthritis undergoing primary TKA/THA was completed at 19 high-volume public and private hospitals. Data were collected prior to surgery and for one-year post-surgery. Logistic regression was undertaken to explore associations between non-compliance with AOA VTE prophylaxis guidelines and symptomatic 90-day VTE outcomes. Data were analysed for 1838 participants from 19 sites. The rate of non-compliance with all clinical guideline recommendations was 20.1% (N = 369), with 14.1% (N = 259) non-compliance for risk-stratified prophylaxis, 35.8% (N = 658) for duration, and 67.8% (N = 1246) for other general recommendations. Symptomatic VTE was experienced up to 90-days post-surgery by 48 people (2.6%). Overall guideline non-compliance (AOR = 0.93, 95%CI = 0.4 to 1.3, p = 0.86) was not associated with a lower risk of symptomatic 90-day VTE. Results were consistent when people with high bleeding risk were excluded (AOR = 0.94, 95%CI = 0.44 to 2.34, p = 0.89). Non-compliance with the AOA VTE prophylaxis guidelines was not associated with risk of 90-day VTE after arthroplasty. This counterintuitive finding is concerning and necessitates a rigorous review of the AOA VTE prevention clinical guideline.
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  • 文章类型: Journal Article
    目的:为髋关节和膝关节置换术的最佳时机制定循证共识建议,以改善患者重要的结局,包括:但不限于,疼痛,函数,感染,住院治疗,有症状和放射学中度至重度骨关节炎或晚期症状性骨坏死伴继发性髋或膝关节炎的患者在1年时死亡,先前曾尝试过非手术治疗,非手术治疗无效的人,并选择接受择期髋关节或膝关节置换术(统称为TJA)。
    方法:我们开发了13个临床相关人群,干预,比较器,结果(PICO)问题。经过系统的文献回顾,建议评估的等级,使用开发和评估(GRADE)方法对证据质量(高,中度,低,或非常低),并创建了证据表。投票小组,包括13名医生和病人,讨论了PICO问题,直到就建议的方向(赞成/反对)和强度(强/有条件)达成共识。
    结果:专家组有条件地建议不要推迟TJA进行额外的非手术治疗,包括物理治疗,非甾体抗炎药,门诊辅助设备,和关节内注射。有条件地建议延迟TJA以减少或停止尼古丁。小组有条件地建议延迟糖尿病患者更好地控制血糖,尽管没有确定具体的措施或水平。人们一致认为肥胖本身并不是拖延的原因,但是应该大力鼓励减肥,应该讨论手术风险的增加。小组有条件地建议严重畸形或骨丢失的患者不要拖延,或患有神经性关节的患者。所有建议的证据都被评为低质量或非常低质量。
    结论:本指南提供了关于TJA在有症状和影像学表现的中度至重度骨关节炎或晚期症状性骨坏死伴继发性关节炎患者中的最佳时机的循证建议,这些患者的非手术治疗对改善患者重要的结局无效。包括疼痛,函数,感染,住院治疗,一年后死亡。我们承认证据的质量较低,主要是由于间接性,并希望未来的研究能够进一步完善建议。
    To develop evidence-based consensus recommendations for the optimal timing of hip and knee arthroplasty to improve patient-important outcomes including, but not limited to, pain, function, infection, hospitalization, and death at 1 year for patients with symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis of the hip or knee who have previously attempted nonoperative therapy, and for whom nonoperative therapy was ineffective, and who have chosen to undergo elective hip or knee arthroplasty (collectively referred to as TJA).
    We developed 13 clinically relevant population, intervention, comparator, outcomes (PICO) questions. After a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the quality of evidence (high, moderate, low, or very low), and evidence tables were created. A Voting Panel, including 13 physicians and patients, discussed the PICO questions until consensus was achieved on the direction (for/against) and strength (strong/conditional) of the recommendations.
    The panel conditionally recommended against delaying TJA to pursue additional nonoperative treatment including physical therapy, nonsteroidal antiinflammatory drugs, ambulatory aids, and intraarticular injections. It conditionally recommended delaying TJA for nicotine reduction or cessation. The panel conditionally recommended delay for better glycemic control for patients who have diabetes mellitus, although no specific measure or level was identified. There was consensus that obesity by itself was not a reason for delay, but that weight loss should be strongly encouraged, and the increase in operative risk should be discussed. The panel conditionally recommended against delay in patients who have severe deformity or bone loss, or in patients who have a neuropathic joint. Evidence for all recommendations was graded as low or very low quality.
    This guideline provides evidence-based recommendations regarding the optimal timing of TJA in patients who have symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis for whom nonoperative therapy was ineffective to improve patient-important outcomes, including pain, function, infection, hospitalization, and death at 1 year. We acknowledge that the evidence is of low quality primarily due to indirectness and hope future research will allow for further refinement of the recommendations.
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  • 文章类型: Journal Article
    目的:为髋关节和膝关节置换术的最佳时机制定循证共识建议,以改善患者重要的结局,包括:但不限于,疼痛,函数,感染,住院治疗,有症状和放射学中度至重度骨关节炎或晚期症状性骨坏死伴继发性髋或膝关节炎的患者在1年时死亡,先前曾尝试过非手术治疗,非手术治疗无效的人,并选择接受择期髋关节或膝关节置换术(统称为TJA)。
    方法:我们开发了13个临床相关人群,干预,比较器,结果(PICO)问题。经过系统的文献回顾,建议评估的等级,使用开发和评估(GRADE)方法对证据质量(高,中度,低,或非常低),并创建了证据表。投票小组,包括13名医生和病人,讨论了PICO问题,直到就建议的方向(赞成/反对)和强度(强/有条件)达成共识。
    结果:专家组有条件地建议不要推迟TJA进行额外的非手术治疗,包括物理治疗,非甾体抗炎药,门诊辅助设备,和关节内注射。有条件地建议延迟TJA以减少或停止尼古丁。小组有条件地建议延迟糖尿病患者更好地控制血糖,尽管没有确定具体的措施或水平。人们一致认为肥胖本身并不是拖延的原因,但是应该大力鼓励减肥,应该讨论手术风险的增加。小组有条件地建议严重畸形或骨丢失的患者不要拖延,或患有神经性关节的患者。所有建议的证据都被评为低质量或非常低质量。
    结论:本指南提供了关于TJA在有症状和影像学表现的中度至重度骨关节炎或晚期症状性骨坏死伴继发性关节炎患者中的最佳时机的循证建议,这些患者的非手术治疗对改善患者重要的结局无效。包括疼痛,函数,感染,住院治疗,一年后死亡。我们承认证据的质量较低,主要是由于间接性,并希望未来的研究能够进一步完善建议。
    To develop evidence-based consensus recommendations for the optimal timing of hip and knee arthroplasty to improve patient-important outcomes including, but not limited to, pain, function, infection, hospitalization, and death at 1 year for patients with symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis of the hip or knee who have previously attempted nonoperative therapy, and for whom nonoperative therapy was ineffective, and who have chosen to undergo elective hip or knee arthroplasty (collectively referred to as TJA).
    We developed 13 clinically relevant population, intervention, comparator, outcomes (PICO) questions. After a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the quality of evidence (high, moderate, low, or very low), and evidence tables were created. A Voting Panel, including 13 physicians and patients, discussed the PICO questions until consensus was achieved on the direction (for/against) and strength (strong/conditional) of the recommendations.
    The panel conditionally recommended against delaying TJA to pursue additional nonoperative treatment including physical therapy, nonsteroidal antiinflammatory drugs, ambulatory aids, and intraarticular injections. It conditionally recommended delaying TJA for nicotine reduction or cessation. The panel conditionally recommended delay for better glycemic control for patients who have diabetes mellitus, although no specific measure or level was identified. There was consensus that obesity by itself was not a reason for delay, but that weight loss should be strongly encouraged, and the increase in operative risk should be discussed. The panel conditionally recommended against delay in patients who have severe deformity or bone loss, or in patients who have a neuropathic joint. Evidence for all recommendations was graded as low or very low quality.
    This guideline provides evidence-based recommendations regarding the optimal timing of TJA in patients who have symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis for whom nonoperative therapy was ineffective to improve patient-important outcomes, including pain, function, infection, hospitalization, and death at 1 year. We acknowledge that the evidence is of low quality primarily due to indirectness and hope future research will allow for further refinement of the recommendations.
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  • 文章类型: Journal Article
    目的:为髋关节和膝关节置换术的最佳时机制定循证共识建议,以改善患者重要的结局,包括:但不限于,疼痛,函数,感染,住院治疗,有症状和放射学中度至重度骨关节炎或晚期症状性骨坏死伴继发性髋或膝关节炎的患者在1年时死亡,先前曾尝试过非手术治疗,非手术治疗无效的人,并选择接受择期髋关节或膝关节置换术(统称为TJA)。
    方法:我们开发了13个临床相关人群,干预,比较器,结果(PICO)问题。经过系统的文献回顾,建议评估的等级,使用开发和评估(GRADE)方法对证据质量(高,中度,低,或非常低),并创建了证据表。投票小组,包括13名医生和病人,讨论了PICO问题,直到就建议的方向(赞成/反对)和强度(强/有条件)达成共识。
    结果:专家组有条件地建议不要推迟TJA进行额外的非手术治疗,包括物理治疗,非甾体抗炎药,门诊辅助设备,和关节内注射。有条件地建议延迟TJA以减少或停止尼古丁。小组有条件地建议延迟糖尿病患者更好地控制血糖,尽管没有确定具体的措施或水平。人们一致认为肥胖本身并不是拖延的原因,但是应该大力鼓励减肥,应该讨论手术风险的增加。小组有条件地建议严重畸形或骨丢失的患者不要拖延,或患有神经性关节的患者。所有建议的证据都被评为低质量或非常低质量。
    结论:本指南提供了关于TJA在有症状和影像学表现的中度至重度骨关节炎或晚期症状性骨坏死伴继发性关节炎患者中的最佳时机的循证建议,这些患者的非手术治疗对改善患者重要的结局无效。包括疼痛,函数,感染,住院治疗,一年后死亡。我们承认证据的质量较低,主要是由于间接性,并希望未来的研究能够进一步完善建议。
    To develop evidence-based consensus recommendations for the optimal timing of hip and knee arthroplasty to improve patient-important outcomes including, but not limited to, pain, function, infection, hospitalization, and death at 1 year for patients with symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis of the hip or knee who have previously attempted nonoperative therapy, and for whom nonoperative therapy was ineffective, and who have chosen to undergo elective hip or knee arthroplasty (collectively referred to as TJA).
    We developed 13 clinically relevant population, intervention, comparator, outcomes (PICO) questions. After a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the quality of evidence (high, moderate, low, or very low), and evidence tables were created. A Voting Panel, including 13 physicians and patients, discussed the PICO questions until consensus was achieved on the direction (for/against) and strength (strong/conditional) of the recommendations.
    The panel conditionally recommended against delaying TJA to pursue additional nonoperative treatment including physical therapy, nonsteroidal antiinflammatory drugs, ambulatory aids, and intraarticular injections. It conditionally recommended delaying TJA for nicotine reduction or cessation. The panel conditionally recommended delay for better glycemic control for patients who have diabetes mellitus, although no specific measure or level was identified. There was consensus that obesity by itself was not a reason for delay, but that weight loss should be strongly encouraged, and the increase in operative risk should be discussed. The panel conditionally recommended against delay in patients who have severe deformity or bone loss, or in patients who have a neuropathic joint. Evidence for all recommendations was graded as low or very low quality.
    This guideline provides evidence-based recommendations regarding the optimal timing of TJA in patients who have symptomatic and radiographic moderate-to-severe osteoarthritis or advanced symptomatic osteonecrosis with secondary arthritis for whom nonoperative therapy was ineffective to improve patient-important outcomes, including pain, function, infection, hospitalization, and death at 1 year. We acknowledge that the evidence is of low quality primarily due to indirectness and hope future research will allow for further refinement of the recommendations.
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  • 文章类型: Systematic Review
    目的:激素替代疗法(HRT),绝经期激素治疗(MHT),含雌激素的药物经常在选择性下肢关节置换术前被停用,基于静脉血栓栓塞(VTE)的感知风险。然而,HRT之间联系的证据,MHT,增加的VTE风险是模棱两可的。本系统评价评估了国际临床实践指南(CPGs)在拒绝HRT或MHT方面的一致性。
    方法:PubMed,谷歌学者,科克伦,并在Ovid数据库中搜索了预CPG,接受选择性下肢关节置换术的HRT和MHT患者的围手术期和术后管理。然后通过对互联网的搜索进行补充。有七个英语国际CPG,来自欧洲和北美,在2000年1月至2023年2月期间发布,根据《研究与评估工具评估指南》(AGREE-II)标准进行了审查,根据系统审查和荟萃分析(PRISMA)清单的首选报告项目。
    结果:所审查的指南揭示了HRT或MHT在关节成形术中的戒断和使用的混合情况,一些关于HRT或MHT(苏格兰校际指南网络)的术前和术后管理的详细建议,而其他人则没有指导(美国胸科医师学院)。回顾这些指南中引用的证据,突出显示HRT或MHT在增加VTE风险方面发挥有限的作用。大多数研究来自1990年代和2000年代。
    结论:根据目前的证据,不含雌激素的经皮HRT或MHT不应该在接受选择性关节置换术的患者中保留,尽管需要进一步的证据来证明扣留含雌激素的形式是合理的。
    BACKGROUND: Hormone replacement therapy (HRT), menopausal hormone therapy (MHT), and estrogen-containing medications are frequently withheld before elective lower limb arthroplasty, based on a perceived risk of venous thromboembolism (VTE). However, evidence linking HRT, MHT, and an increased VTE risk is equivocal. This systematic review evaluated the concordance of international clinical practice guidelines (CPGs) on the withholding of HRT or MHT.
    METHODS: The PubMed, Google Scholar, Cochrane, and Ovid databases were searched for CPGs for the preoperative, perioperative, and postoperative management of patients on HRT and MHT undergoing elective lower limb arthroplasty. This was supplemented by an internet search. There were 7 international CPGs in English, from Europe and North America, published between January 2000 and February 2023 reviewed against the Appraisal of Guidelines for Research & Evaluation Instrument (AGREE-II) criteria, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist.
    RESULTS: The guidelines reviewed revealed a mixed picture on HRT or MHT withdrawal and use in arthroplasty, with some featuring detailed advice on the preoperative and postoperative management of HRT or MHT (Scottish Intercollegiate Guidelines Network), while others featured no guidance (American College of Chest Physicians). The evidence referenced in these guidelines highlighted studies showing HRT or MHT to play a limited role in increasing VTE risk, with most studies from the 1990s and 2000s.
    CONCLUSIONS: Based on current evidence, non-estrogen-containing transdermal HRT or MHT should not be withheld in patients undergoing elective joint arthroplasty, though further evidence is required to justify withholding estrogen-containing forms.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    目的:对于全膝关节置换术(TKA)后如何使用康复访视尚无共识。我们寻求为TKA后的门诊康复就诊提供专家建议。设计:德尔菲研究。方法:首先,我们制定了一系列初步访问使用建议,特定于患者的恢复状态(即,慢,典型的,或快速恢复)和手术后的时间。然后,我们邀请了49位TKA专家参加Delphi小组。在第一轮中,我们对小组成员进行了调查,了解他们与每项初步建议的协议程度。我们根据需要进行了额外的德尔菲回合,以建立共识,我们使用RAND/UCLA方法定义。我们根据小组成员的反馈和上一轮的回应更新了每一轮的调查。结果:30名小组成员同意参加,29名小组成员完成了2轮Delphi。小组就有关访问频率的建议达成共识,访问时间,以及远程康复的使用。专家小组建议,无论恢复状态如何,应在术后第一个月以每周2次的频率在手术后1周内开始门诊康复。小组根据患者术后2至3个月的恢复状况建议不同的就诊频率。小组同意,可以建议大多数TKA后的患者进行远程康复治疗,但不适用于恢复缓慢的患者。结论:我们使用Delphi程序为TKA后的门诊康复就诊提供专家建议。我们认为这些建议可以帮助患者根据自己的喜好决定如何使用就诊。J正交运动物理学,2023年;53(9):1-9。Epub:2023年7月10日。doi:10.2519/jospt.2023.11840。
    OBJECTIVE: There is no consensus for how to use rehabilitation visits after total knee arthroplasty (TKA). We sought to develop expert recommendations for outpatient rehabilitation visit usage after TKA. DESIGN: Delphi study. METHODS: First, we developed a broad list of preliminary visit usage recommendations, which were specific to patients\' recovery status (ie, slow, typical, or fast recovery) and time since surgery. We then invited 49 TKA experts to participate on a Delphi panel. During round 1, we surveyed panelists regarding their level of agreement with each preliminary recommendation. We conducted additional Delphi rounds as needed to build consensus, which we defined using the RAND/UCLA method. We updated the survey each round based on panelist feedback and responses from the previous round. RESULTS: Thirty panelists agreed to participate, and 29 panelists completed 2 Delphi rounds. The panel reached consensus on recommendations related to visit frequency, visit timing, and the use of telerehabilitation. The panel recommended that outpatient rehabilitation should begin within 1 week after surgery at a frequency of 2 times per week for the first postoperative month regardless of recovery status. The panel recommended different visit frequencies depending on the patient\'s recovery status for postoperative months 2 to 3. The panel agreed that telerehabilitation can be recommended for most patients after TKA, but not for patients recovering slowly. CONCLUSION: We used the Delphi process to develop expert recommendations for the use of outpatient rehabilitation visits after TKA. We envision these recommendations could help patients decide how to use visits based on their own preferences. J Orthop Sports Phys Ther 2023;53(9):1-9. Epub: 10 July 2023. doi:10.2519/jospt.2023.11840.
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