背景:梨已被世界广泛用作甜食和营养食品以及民间药物超过两千年。
方法:我们从古代文献到当前报道进行了综述,以提取梨的循证功能。
结果:我们发现梨含有许多活性化合物,例如,黄酮类化合物,三萜类,和酚酸,包括熊果苷,绿原酸,苹果酸,等。大多数研究人员都认为有益的化合物集中在果皮中。从各种体外,在体内,和人类研究,梨的药用功能可以概括为抗糖尿病,-肥胖,-高脂血症,-炎症,-诱变,和-致癌作用,外源性物质的解毒,呼吸和心脏保护作用,和皮肤美白效果。因此,在患有多种基础疾病的高易感人群中,梨似乎对预防新冠肺炎或PM2.5甚至是有效的。
结论:对于当前或后Covid-19时代,梨有可能成为传染性和非传染性疾病的功能性食品或药物。
BACKGROUND: Pears have been world-widely used as a sweet and nutritious food and a folk medicine for more than two millennia.
METHODS: We conducted a
review from ancient literatures to current reports to extract evidence-based functions of pears.
RESULTS: We found that pears have many active compounds, e.g., flavonoids, triterpenoids, and phenolic acids including
arbutin, chlorogenic acid, malaxinic acid, etc. Most of researchers agree that the beneficial compounds are concentrated in the peels. From various in vitro, in vivo, and human studies, the medicinal functions of pears can be summarized as anti-diabetic,-obese, -hyperlipidemic, -inflammatory, -mutagenic, and -carcinogenic effects, detoxification of xenobiotics, respiratory and cardio-protective effects, and skin whitening effects. Therefore, pears seem to be even effective for prevention from Covid-19 or PM2.5 among high susceptible people with multiple underlying diseases.
CONCLUSIONS: For the current or post Covid-19 era, pears have potential for functional food or medicine for both of communicable and non-communicable disease.