UNASSIGNED:使用三种营养评估方法评估计划进行上颌切除和修复的患者的营养状况(NS)。
UNASSIGNED:这项纵向研究纳入了18名符合纳入和排除标准的计划上颌骨切除术患者。NS在五个阶段进行评估:手术前(S0),术后2周(S1),插入中间闭塞器(S2)后3个月,就在制造最终闭塞器(S3)之前,使用两种营养评估工具,即患者生成的主观整体评估(PG-SGA)和营养风险指数(NRI),以及身体成分指标,即体重指数(BMI),无脂肪质量(FFM),全身水(TBW),骨骼肌质量(SMM)和骨骼肌质量指数(SMMI)。为了确定不同时间点患者营养状况的变化,使用了带有Bonferroni的重复测量ANOVA事后调整。
未经批准:在18名患者中,12人完成了这项研究。上颌骨切除术患者NS显著恶化(p<.05),直至S2期。在S3,与S2阶段相比,出现了显着改善,但仍明显低于手术前水平。然而,在S4阶段,除PG-SGA(p<.001)和SMM(p=.044)外,所有参数均与S0具有统计学可比性(p>.05)。
UNASSIGNED:由于手术发病率和放疗(RT)的不良反应,上颌骨切除术患者的NS在手术后恶化,但随着手术后愈合而改善,由于适应良好的闭孔假体,RT后遗症的解决和口腔功能的改善。
UNASSIGNED: To evaluate the nutritional status (NS) of patients planned for maxillectomy and prosthodontic rehabilitation using three nutritional assessment methods.
UNASSIGNED: This longitudinal
study enrolled 18 planned maxillectomy patients following the inclusion and exclusion criteria. NS was evaluated at five stages: before surgery (S0), 2 weeks after surgery (S1), 3 months after insertion of intermediate obturator (S2), just before fabrication of definitive obturator (S3), and 3 months after insertion of definitive obturator (S4) using two nutritional assessment tools i.e. Patient Generated -Subjective Global Assessment (PG-SGA) &Nutritional risk index (NRI); and body composition indicators i.e. body mass index (BMI), fat free mass (FFM), total body water (TBW), skeletal muscle mass (SMM) and skeletal muscle mass index (SMMI).To determine the changes in patient\'s nutritional status among different time points Repeated Measure ANOVA with Bonferroni post hoc adjustments was used.
UNASSIGNED: Out of 18 patients, 12 were completed the
study. NS of maxillectomy patients deteriorates significantly (p < .05) till stage S2. At S3, significant improvement occurred as compared to stage S2, but it remained significantly less than pre-surgical level. However, at stage S4, all parameters were statistically comparable to S0 (p > .05) except for PG-SGA (p < .001) and SMM (p = .044).
UNASSIGNED: NS of maxillectomy patients worsen post surgically due to surgical morbidity and adverse effects of radiotherapy (RT) but improves with post-surgical healing, resolution of sequel of RT and improved oral function due to well-adapted obturator prosthesis.