BACKGROUND: In recent years, there has been a notable increase of migratory movements into Europe with the arrival of not (reliably) documented young individuals within EU-Member States. Accordingly, the need for forensic age assessments likewise increased in order to administratively differentiate along the legally relevant cut-off age of 18 completed years. The objective of our study was to analyse the expert reports of forensic age estimation issued in Barcelona between 2011 and 2018.
METHODS: In all cases, data on the medical history, physical examination, radiology of the left hand and orthopantomography were collected. In cases without third molars and a complete ossification of the hand, a CT scan of the clavicles was also performed.
RESULTS: A total of 2754 expert reports were evaluated; 96.7% were males, the majority were of North African origin, mainly from Morocco (63.6%), and 19.6% were sub-Saharan Africans; 65.4% had a level of bone maturation corresponding to the last three standards of Greulich and Pyle. Most cases had mineralization of the third molar corresponding to the F, G or H stages of Demirjian. In 85.9%, there was a correspondence between bone and dental age. A total of 28.8% of the subjects were evaluated as being aged over 18 years; 86.2% of North Africans were considered to be younger than 18, and 82% of sub-Saharan Africans were considered to be over 18 years old.
CONCLUSIONS: In Barcelona, most of the subjects evaluated were male and North African, and 71.2% of the cases were considered to be minors.

Celiac disease (CD) is an immune-related enteropathy triggered by gluten ingestion in susceptible individuals. Oral manifestations of CD have been frequently described, although reports on dental maturity (DM) are scant. Thus, the aim of this study is to assess the prevalence of DM in CD patients and to test for possible predictors.
This is a case-control study of children with CD and healthy controls between 2017 and 2020. A panoramic radiograph and comprehensive oral examination were performed for each participant. Dental age (DA) was measured according to Demirjian\'s method and DM was calculated by subtracting the chronological age (CA) from the DA. Statistical analysis was performed to compare the DM between CD patients and controls, and a multivariate analysis was utilized to look for predictors of DM.
Two-hundred and eight participants (104 children with CD, and 104 healthy controls) were incorporated. The mean age for CD patients was 10.67 ± 2.40 years, and 10.69 ± 2.37 years for healthy controls (P = 0.971). CD patients had a higher prevalence of delayed DM than controls (62.5% vs. 3%, respectively). They also had a greater delay in DM than controls (- 7.94 ± 10.94 vs. 6.99 ± 8.77, P < 0.001). A multivariate analysis identified age between 6 and 7 years (β ± SE = 16.21 ± 2.58, P < 0.001), as the only predictor for DM.
CD patients had a greater prevalence of delayed DM than controls. No predictors for DM could be found, except young age.

OBJECTIVE: To assess dental maturation in children with amelogenesis imperfecta (AI) and compare their estimated dental age with the age of non-AI children.
RESULTS: Panoramic radiographs of children with (n = 27) and without (n = 54) AI were retrospectively collected in the ratio of 1:2. The former consisted of case group, while the latter figured as control group. Both groups were paired by sex and age (P > .05). Dental maturation was assessed in each radiograph using Demirjian\'s staging technique and Willems\' method. Intra- and interexaminer reproducibility reached >0.8. The mean estimated dental age in subjects with AI was 12.5 ± 2.69 years, while in subjects without AI it was 11.73 ± 2.48 years (P = .21). The comparison of mean chronological (12.26 ± 2.6 years) and estimated dental age (12.5 ± 2.69 years) in subjects with AI did not reveal statistically significant differences (P = .38).
CONCLUSIONS: This study highlights the similarity of dental maturation between subjects with and without AI from the radiographic perspective of crown-root formation.

Age estimation is widely applied in several clinical and forensic fields. The radiographic evaluation of dental development is one of the most accepted tools for this purpose. Among the different methods proposed, Demirjian\'s method was the most extensively used and tested in the medical literature revealing that the original standards for the French-Canadian population tends to over-estimate the age of different population groups. The aims of this study were to evaluate the applicability of the Demirjian method in a sample of Italian children with Down syndrome (DS) and to compare the data with age and gender matched healthy subjects (non-DS). A retrospective study was performed on 146 orthopantomograms of DS individuals aged 6.3-16 years. The mean chronological age (CA) and the mean dental age (DA) were calculated. Using Cohen\'s kappa statistics, the inter- and intra-examiner agreement was reported as good (k = 0.75) and very good (k = 0.86). The differences between CAs and DAs were statistically significant for males and females (Wilcoxon Signed Rank test; p < 0.05). The median overestimation was 0.6 years in males and 0.9 years in females. Demirjian\'s method is unsuitable for dental age estimation in DS individuals. The same trend in overestimation was found in the control group. Comparing DS and non-DS subjects, the differences between DAs were not statistically significant for both males and females revealing that the dental development process is similar.

This case study reports the anthropological analysis of bones remains discovered on Riou Island (Marseille, France) and the story of two World War II fighter pilots. The discovery of bones on \"The Fountain of the Greeks\" square on Riou Island occurred in the 1960\'s and a first anthropological study described a 35-year-old man, about 1.77 m tall, buried since an estimated period between the 13th and 16th centuries. The case was \"closed\" and the bones were considered as isolated archaeological remains. Few years later, near the coasts of Riou Island, parts of two planes were discovered. One was from of a German Messerschmitt Bf 109 F-4 of the Luftwaffe piloted by Prince Alexis fürst zu Bentheim und Steinfurt, and the other from a French P-38 Lightning F-5 B piloted by Antoine de Saint-Exupery. Therefore, the identification of the skeletal remains mentioned above was then thought to be perhaps one of the two World War II pilots. In this particular context we performed forensic and molecular biology analyses to resolve this identification.

Forensic examination of human remains is a complex process that relies on the contribution of multidisciplinary forensic medicine specialties. Here we present a complex forensic case regarding a double murder whose victims were found almost completely skeletonized. Post-mortem investigations allowed us to define the biological profile of the two bodies (ancestry, sex, age and stature), to discover their identity through forensic DNA analysis, and to detect peri-mortem injuries caused by firearms and stabbing weapons. Three men were recognized as involved in the crime and two of them were condemned to life imprisonment for homicide. The judges accepted the reconstruction of the crime promoted by the Prosecutor (double firearm murder).

OBJECTIVE: Many reports suggest that children with cleft lip and palate (CLP) have delayed dental development and asymmetrical timing of tooth-pair formation. We aimed to investigate the dental maturation of permanent teeth in children with complete unilateral CLP (UCLP) and compare the findings with non-CLP children.
METHODS: This case-control study used 115 radiographs of children with complete UCLP and controls (non-CLP children matched on age, gender and ethnicity) from a hospital-based dental clinic in Singapore.
METHODS: Orthopantomographs of 60 children with complete UCLP (5-9 years old) and 55 children (9-13 years old) from the same cohort were investigated using the Demirjian\'s method and compared with controls to determine if there were any differences in dental maturation with age.
RESULTS: Delayed dental maturation was found in the 5- to 9-year-old children with UCLP compared to controls by 0.55 years (standard deviation: 0.75) (P<.001). There was no significant difference between the dental maturation of children with UCLP and controls in the 9- to 13-year-old group (P=.744). The group with UCLP had higher risk of asymmetrically developing tooth pairs than the control group for both age groups (P<.001).
CONCLUSIONS: No difference in dental maturation between UCLP and controls in the 9- to 13-year-old group was found. However, there was diametrical difference in dental maturation in the 5- to 9-year-old group, which attenuated as they grew older. There was a consistently higher risk of asymmetrical tooth formation in children with UCLP than in controls.

The presented paper illustrates the significance of dental documentation which played a key role in the process of identification of two unknown male cadavers by means of dental features examination. Efficient operations of the district prosecutor\'s office, which in both cases provided ante mortem dental documentation of a missing person likely to be the victim, led to double positive identification. In the first presented case dental examination proved to be more effective than genetics and contributed to closure of the identification procedures. In the second case it confirmed identity equally with genetics. In addition, the paper discusses the basic rules of medical records handling and storage.
W pracy przedstawiono kluczową rolę, jaką odegrała dokumentacja stomatologiczna w procesie ustalania tożsamości zwłok NN dwóch mężczyzn na podstawie badania cech uzębienia. Sprawne działania Prokuratury Rejonowej, która w obydwu przypadkach dostarczyła zażyciową dokumentację stomatologiczną osoby zaginionej typowanej jako ofiara, umożliwiły przeprowadzenie porównawczego badania odontologicznego, co ostatecznie doprowadziło do zidentyfikowania obydwóch mężczyzn. W pierwszym z prezentowanych przypadków badania stomatologiczne odebrały palmę pierwszeństwa genetycznym i przyczyniły się do szybkiego zakończenia procedur identyfikacyjnych, w drugim zaś w sposób równorzędny z genetycznymi potwierdziły tożsamość ofiary. Dodatkowo w pracy omówiono podstawowe zasady prawidłowego prowadzenia i przechowywania dokumentacji medycznej.

In order to establish identity of asylum seekers, part of which is age clarification, administrative authorities are obliged to investigate the credibility of allegations based on the usual means of evidence to determine the applicable legal background. In case of serious doubts concerning age minority declaration, medical expert opinion builds the key proof bound by a complex framework consisting of EU regulations, domestic legal backgrounds and the scientific \'state of the art,\' the latter being largely influenced by the pursuit of the German \'Study Group on Forensic Age Diagnostics.\' Our application example demonstrates the exceptional value of its guidelines serving evidence-based understanding of the age issue in borderline adults within the asylum context. The results deriving from a substantial number of cases disclose an unequivocal inclination of age-disputed male refugees towards concluding somatic development despite a tendency of low lying age reports.

Dental identification of skeletal remains frequently relies on data comparison. Comparative dental identification is used to establish with a high degree of certainty that the remains of a corpse and a person represented by ante-mortem dental records are the same individual. There is no minimum number of concordant points necessary to perform a positive identification; rather, each case is unique and should be treated as such. In this paper, we present a report of a case in which positive identification was made by a paramolar tubercle in both upper first deciduous molars.